stefania trazzi
stefania trazzi
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Early pharmacotherapy restores neurogenesis and cognitive performance in the Ts65Dn mouse model for Down syndrome
P Bianchi, E Ciani, S Guidi, S Trazzi, D Felice, G Grossi, M Fernandez, ...
Journal of Neuroscience 30 (26), 8769-8779, 2010
DNMT3B interacts with constitutive centromere protein CENP-C to modulate DNA methylation and the histone code at centromeric regions
S Gopalakrishnan, BA Sullivan, S Trazzi, G Della Valle, KD Robertson
Human molecular genetics 18 (17), 3178-3193, 2009
APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome
S Trazzi, VM Mitrugno, E Valli, C Fuchs, S Rizzi, S Guidi, G Perini, ...
Human molecular genetics 20 (8), 1560-1573, 2011
Loss of CDKL5 impairs survival and dendritic growth of newborn neurons by altering AKT/GSK-3β signaling
C Fuchs, S Trazzi, R Torricella, R Viggiano, M De Franceschi, ...
Neurobiology of disease 70, 53-68, 2014
CENP-C binds the alpha-satellite DNA in vivo at specific centromere domains
V Politi, G Perini, S Trazzi, A Pliss, I Raska, WC Earnshaw, GD Valle
Journal of cell science 115 (11), 2317-2327, 2002
HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder
S Trazzi, C Fuchs, R Viggiano, M De Franceschi, E Valli, P Jedynak, ...
Human molecular genetics 25 (18), 3887-3907, 2016
CB1 cannabinoid receptors increase neuronal precursor proliferation through AKT/glycogen synthase kinase-3β/β-catenin signaling
S Trazzi, M Steger, VM Mitrugno, R Bartesaghi, E Ciani
Journal of Biological Chemistry 285 (13), 10098-10109, 2010
Short-and long-term effects of neonatal pharmacotherapy with epigallocatechin-3-gallate on hippocampal development in the Ts65Dn mouse model of Down syndrome
F Stagni, A Giacomini, M Emili, S Trazzi, S Guidi, M Sassi, E Ciani, ...
Neuroscience 333, 277-301, 2016
Early Pharmacotherapy with Fluoxetine Rescues Dendritic Pathology in the Ts65Dn Mouse Model of D own Syndrome
S Guidi, F Stagni, P Bianchi, E Ciani, E Ragazzi, S Trazzi, G Grossi, ...
Brain pathology 23 (2), 129-143, 2013
The C-terminal domain of CENP-C displays multiple and critical functions for mammalian centromere formation
S Trazzi, G Perini, R Bernardoni, M Zoli, JC Reese, A Musacchio, ...
PloS one 4 (6), e5832, 2009
Inhibition of GSK3β rescues hippocampal development and learning in a mouse model of CDKL5 disorder
C Fuchs, R Rimondini, R Viggiano, S Trazzi, M De Franceschi, ...
Neurobiology of Disease 82, 298-310, 2015
The amyloid precursor protein (APP) triplicated gene impairs neuronal precursor differentiation and neurite development through two different domains in the Ts65Dn mouse model …
S Trazzi, C Fuchs, E Valli, G Perini, R Bartesaghi, E Ciani
Journal of Biological Chemistry 288 (29), 20817-20829, 2013
CDKL5, a novel MYCN-repressed gene, blocks cell cycle and promotes differentiation of neuronal cells
E Valli, S Trazzi, C Fuchs, D Erriquez, R Bartesaghi, G Perini, E Ciani
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1819 (11-12 …, 2012
Functional cooperation between TrkA and p75NTR accelerates neuronal differentiation by increased transcription of GAP-43 and p21 (CIP/WAF) genes via ERK1/2 and AP-1 activities
D Diolaiti, R Bernardoni, S Trazzi, A Papa, A Porro, F Bono, JM Herbert, ...
Experimental cell research 313 (14), 2980-2992, 2007
CDKL5 protein substitution therapy rescues neurological phenotypes of a mouse model of CDKL5 disorder
S Trazzi, M De Franceschi, C Fuchs, S Bastianini, R Viggiano, L Lupori, ...
Human molecular genetics 27 (9), 1572-1592, 2018
In vivo functional dissection of human inner kinetochore protein CENP-C
S Trazzi, R Bernardoni, D Diolaiti, V Politi, WC Earnshaw, G Perini, ...
Journal of structural biology 140 (1-3), 39-48, 2002
Inhibition of APP gamma-secretase restores Sonic Hedgehog signaling and neurogenesis in the Ts65Dn mouse model of Down syndrome
A Giacomini, F Stagni, S Trazzi, S Guidi, M Emili, E Brigham, E Ciani, ...
Neurobiology of disease 82, 385-396, 2015
Heterozygous CDKL5 knockout female mice are a valuable animal model for CDKL5 disorder
C Fuchs, L Gennaccaro, S Trazzi, S Bastianini, S Bettini, VL Martire, ...
Neural Plasticity 2018, 2018
APP-dependent alteration of GSK3β activity impairs neurogenesis in the Ts65Dn mouse model of Down syndrome
S Trazzi, C Fuchs, M De Franceschi, VM Mitrugno, R Bartesaghi, E Ciani
Neurobiology of disease 67, 24-36, 2014
Treatment with the GSK3‐beta inhibitor Tideglusib improves hippocampal development and memory performance in juvenile, but not adult, Cdkl5 knockout mice
C Fuchs, N Fustini, S Trazzi, L Gennaccaro, R Rimondini, E Ciani
European Journal of Neuroscience 47 (9), 1054-1066, 2018
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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