Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-β pathway JR Grainger, KA Smith, JP Hewitson, HJ McSorley, Y Harcus, KJ Filbey, ... Journal of Experimental Medicine 207 (11), 2331-2341, 2010 | 560 | 2010 |
Commensal-pathogen interactions in the intestinal tract: lactobacilli promote infection with, and are promoted by, helminth parasites LA Reynolds, KA Smith, KJ Filbey, Y Harcus, JP Hewitson, SA Redpath, ... Gut microbes 5 (4), 522-532, 2014 | 256 | 2014 |
Immunity to the model intestinal helminth parasite Heligmosomoides polygyrus LA Reynolds, KJ Filbey, RM Maizels Seminars in immunopathology 34, 829-846, 2012 | 238 | 2012 |
Helminth‐induced CD19+CD23hi B cells modulate experimental allergic and autoimmune inflammation MS Wilson, MD Taylor, MT O'Gorman, A Balic, TA Barr, K Filbey, ... European journal of immunology 40 (6), 1682-1696, 2010 | 236 | 2010 |
CCR7-dependent trafficking of RORγ+ ILCs creates a unique microenvironment within mucosal draining lymph nodes EC Mackley, S Houston, CL Marriott, EE Halford, B Lucas, V Cerovic, ... Nature communications 6 (1), 5862, 2015 | 209 | 2015 |
A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells CJC Johnston, DJ Smyth, RB Kodali, MPJ White, Y Harcus, KJ Filbey, ... Nature communications 8 (1), 1741, 2017 | 178 | 2017 |
Proteomic analysis of secretory products from the model gastrointestinal nematode Heligmosomoides polygyrus reveals dominance of venom allergen-like (VAL) proteins JP Hewitson, Y Harcus, J Murray, M van Agtmaal, KJ Filbey, JR Grainger, ... Journal of proteomics 74 (9), 1573-1594, 2011 | 178 | 2011 |
ILC2s and T cells cooperate to ensure maintenance of M2 macrophages for lung immunity against hookworms T Bouchery, R Kyle, M Camberis, A Shepherd, K Filbey, A Smith, M Harvie, ... Nature communications 6 (1), 6970, 2015 | 175 | 2015 |
HpARI protein secreted by a helminth parasite suppresses interleukin-33 M Osbourn, DC Soares, F Vacca, ES Cohen, IC Scott, WF Gregory, ... Immunity 47 (4), 739-751. e5, 2017 | 165 | 2017 |
Innate and adaptive type 2 immune cell responses in genetically controlled resistance to intestinal helminth infection KJ Filbey, JR Grainger, KA Smith, L Boon, N Van Rooijen, Y Harcus, ... Immunology and cell biology 92 (5), 436-448, 2014 | 149 | 2014 |
Immune modulation and modulators in Heligmosomoides polygyrus infection RM Maizels, JP Hewitson, J Murray, YM Harcus, B Dayer, KJ Filbey, ... Experimental parasitology 132 (1), 76-89, 2012 | 145 | 2012 |
Alterations in T and B cell function persist in convalescent COVID-19 patients HA Shuwa, TN Shaw, SB Knight, K Wemyss, FA McClure, L Pearmain, ... Med 2 (6), 720-735. e4, 2021 | 133 | 2021 |
Suppression of type 2 immunity and allergic airway inflammation by secreted products of the helminth H eligmosomoides polygyrus HJ McSorley, MT O'Gorman, N Blair, TE Sutherland, KJ Filbey, ... European journal of immunology 42 (10), 2667-2682, 2012 | 128 | 2012 |
Concerted activity of IgG1 antibodies and IL-4/IL-25-dependent effector cells trap helminth larvae in the tissues following vaccination with defined secreted antigens … JP Hewitson, KJ Filbey, J Esser-von Bieren, M Camberis, C Schwartz, ... PLoS pathogens 11 (3), e1004676, 2015 | 80 | 2015 |
Low-level regulatory T-cell activity is essential for functional type-2 effector immunity to expel gastrointestinal helminths KA Smith, KJ Filbey, LA Reynolds, JP Hewitson, Y Harcus, L Boon, ... Mucosal immunology 9 (2), 428-443, 2016 | 74 | 2016 |
Secretion of protective antigens by tissue-stage nematode larvae revealed by proteomic analysis and vaccination-induced sterile immunity JP Hewitson, AC Ivens, Y Harcus, KJ Filbey, HJ McSorley, J Murray, ... PLoS pathogens 9 (8), e1003492, 2013 | 66 | 2013 |
Heligmosomoides polygyrus elicits a dominant nonprotective antibody response directed against restricted glycan and peptide epitopes JP Hewitson, KJ Filbey, JR Grainger, AA Dowle, M Pearson, J Murray, ... The Journal of Immunology 187 (9), 4764-4777, 2011 | 62 | 2011 |
C-type lectins from the nematode parasites Heligmosomoides polygyrus and Nippostrongylus brasiliensis Y Harcus, G Nicoll, J Murray, K Filbey, N Gomez-Escobar, RM Maizels Parasitology International 58 (4), 461-470, 2009 | 54 | 2009 |
Intestinal helminth infection promotes IL-5- and CD4+ T cell-dependent immunity in the lung against migrating parasites KJ Filbey, M Camberis, J Chandler, R Turner, AJ Kettle, RM Eichenberger, ... Mucosal immunology 12 (2), 352-362, 2019 | 48 | 2019 |
The Study of Host Immune Responses Elicited by the Model Murine Hookworms Nippostrongylus brasiliensis and Heligmosomoides polygyrus T Bouchery, B Volpe, K Shah, L Lebon, K Filbey, G LeGros, N Harris Current protocols in mouse biology 7 (4), 236-286, 2017 | 41 | 2017 |