Bryan R. Cullen
Bryan R. Cullen
Professor of Molecular Genetics and Microbiology, Duke University
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Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
R Yi, Y Qin, IG Macara, BR Cullen
Genes & development 17 (24), 3011-3016, 2003
Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs
X Cai, CH Hagedorn, BR Cullen
Rna 10 (12), 1957-1966, 2004
The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA
MH Malim, J Hauber, SY Le, JV Maizel, BR Cullen
Nature 338 (6212), 254-257, 1989
Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells
Y Zeng, EJ Wagner, BR Cullen
Molecular cell 9 (6), 1327-1333, 2002
MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms
Y Zeng, R Yi, BR Cullen
Proceedings of the National Academy of Sciences 100 (17), 9779-9784, 2003
Identification of the envelope V3 loop as the primary determinant of cell tropism in HIV-1
SS Hwang, TJ Boyle, HK Lyerly, BR Cullen
Science 253 (5015), 71-74, 1991
Use of eukaryotic expression technology in the functional analysis of cloned genes
BR Cullen
Methods in enzymology 152, 1987
Transcription and processing of human microRNA precursors
BR Cullen
Molecular cell 16 (6), 861-865, 2004
Functional dissection of the HIV-1 Rev trans-activator—derivation of a trans-dominant repressor of Rev function
MH Malim, S Bhnlein, J Hauber, BR Cullen
Cell 58 (1), 205-214, 1989
Secreted placental alkaline phosphatase: a powerful new quantitative indicator of gene expression in eukaryotic cells
J Berger, J Hauber, R Hauber, R Geiger, BR Cullen
Gene 66 (1), 1-10, 1988
Trans-activation of human immunodeficiency virus occurs via a bimodal mechanism
BR Cullen
Cell 46 (7), 973-982, 1986
Sequence requirements for micro RNA processing and function in human cells
Y Zeng, BR Cullen
Rna 9 (1), 112-123, 2003
MicroRNAs expressed by herpes simplex virus 1 during latent infection regulate viral mRNAs
JL Umbach, MF Kramer, I Jurak, HW Karnowski, DM Coen, BR Cullen
Nature 454 (7205), 780-783, 2008
Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha
Y Zeng, R Yi, BR Cullen
The EMBO journal 24 (1), 138-148, 2005
Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells
X Cai, S Lu, Z Zhang, CM Gonzalez, B Damania, BR Cullen
Proceedings of the National Academy of Sciences 102 (15), 5570-5575, 2005
A viral microRNA functions as an orthologue of cellular miR-155
E Gottwein, N Mukherjee, C Sachse, C Frenzel, WH Majoros, JTA Chi, ...
Nature 450 (7172), 1096-1099, 2007
Novel interleukin-2 receptor subunit detected by cross-linking under high-affinity conditions
M Sharon, RD Klausner, BR Cullen, R Chizzonite, WJ Leonard
Science 234 (4778), 859-863, 1986
Epstein–Barr virus microRNAs are evolutionarily conserved and differentially expressed
X Cai, A Schfer, S Lu, JP Bilello, RC Desrosiers, R Edwards, ...
PLoS pathog 2 (3), e23, 2006
Structural requirements for pre-microRNA binding and nuclear export by Exportin 5
Y Zeng, BR Cullen
Nucleic acids research 32 (16), 4776-4785, 2004
Viruses, microRNAs, and host interactions
RL Skalsky, BR Cullen
Annual review of microbiology 64, 123-141, 2010
Il sistema al momento non pu eseguire l'operazione. Riprova pi tardi.
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