Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions AP Bracken, N Dietrich, D Pasini, KH Hansen, K Helin Genes & development 20 (9), 1123-1136, 2006 | 1331 | 2006 |
EZH2 is downstream of the pRB‐E2F pathway, essential for proliferation and amplified in cancer AP Bracken, D Pasini, M Capra, E Prosperini, E Colli, K Helin The EMBO journal 22 (20), 5323-5335, 2003 | 1213 | 2003 |
UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development K Agger, PAC Cloos, J Christensen, D Pasini, S Rose, J Rappsilber, ... Nature 449 (7163), 731-734, 2007 | 1190 | 2007 |
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity K Williams, J Christensen, MT Pedersen, JV Johansen, PAC Cloos, ... Nature 473 (7347), 343, 2011 | 915 | 2011 |
E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis H Müller, AP Bracken, R Vernell, MC Moroni, F Christians, E Grassilli, ... Genes & development 15 (3), 267-285, 2001 | 864 | 2001 |
Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity D Pasini, AP Bracken, MR Jensen, EL Denchi, K Helin The EMBO journal 23 (20), 4061-4071, 2004 | 863 | 2004 |
The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells AP Bracken, D Kleine-Kohlbrecher, N Dietrich, D Pasini, G Gargiulo, ... Genes & development 21 (5), 525-530, 2007 | 844 | 2007 |
The putative oncogene GASC1 demethylates tri-and dimethylated lysine 9 on histone H3 PAC Cloos, J Christensen, K Agger, A Maiolica, J Rappsilber, T Antal, ... Nature 442 (7100), 307-311, 2006 | 767 | 2006 |
A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F K Helin, JA Lees, M Vidal, N Dyson, E Harlow, A Fattaey Cell 70 (2), 337-350, 1992 | 749 | 1992 |
Apaf-1 is a transcriptional target for E2F and p53 MC Moroni, ES Hickman, EL Denchi, G Caprara, E Colli, F Cecconi, ... Nature cell biology 3 (6), 552-558, 2001 | 732 | 2001 |
Molecular mechanisms and potential functions of histone demethylases SM Kooistra, K Helin Nature reviews Molecular cell biology 13 (5), 297-311, 2012 | 720 | 2012 |
Transcriptional regulation by Polycomb group proteins L Di Croce, K Helin Nature structural & molecular biology 20 (10), 1147, 2013 | 687 | 2013 |
The polycomb group protein Suz12 is required for embryonic stem cell differentiation D Pasini, AP Bracken, JB Hansen, M Capillo, K Helin Molecular and cellular biology 27 (10), 3769-3779, 2007 | 686 | 2007 |
Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease PAC Cloos, J Christensen, K Agger, K Helin Genes & development 22 (9), 1115-1140, 2008 | 679 | 2008 |
A model for transmission of the H3K27me3 epigenetic mark KH Hansen, AP Bracken, D Pasini, N Dietrich, SS Gehani, A Monrad, ... Nature cell biology 10 (11), 1291-1300, 2008 | 661 | 2008 |
Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein. L Zhu, S van den Heuvel, K Helin, A Fattaey, M Ewen, D Livingston, ... Genes & development 7 (7a), 1111-1125, 1993 | 623 | 1993 |
Polycomb group proteins: navigators of lineage pathways led astray in cancer AP Bracken, K Helin Nature Reviews Cancer 9 (11), 773-784, 2009 | 589 | 2009 |
Regulation of cell proliferation by the E2F transcription factors K Helin Current opinion in genetics & development 8 (1), 28-35, 1998 | 587 | 1998 |
Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein. K Helin, E Harlow, A Fattaey Molecular and cellular biology 13 (10), 6501-6508, 1993 | 585 | 1993 |
E2F target genes: unraveling the biology AP Bracken, M Ciro, A Cocito, K Helin Trends in biochemical sciences 29 (8), 409-417, 2004 | 549 | 2004 |