A vaccine targeting mutant IDH1 induces antitumour immunity T Schumacher, L Bunse, S Pusch, F Sahm, B Wiestler, J Quandt, O Menn, ... Nature 512 (7514), 324-327, 2014 | 766 | 2014 |
Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate L Bunse, S Pusch, T Bunse, F Sahm, K Sanghvi, M Friedrich, D Alansary, ... Nature medicine 24 (8), 1192-1203, 2018 | 422 | 2018 |
Cancer immunotherapy by targeting IDO1/TDO and their downstream effectors M Platten, N von Knebel Doeberitz, I Oezen, W Wick, K Ochs Frontiers in immunology 5, 123050, 2015 | 359 | 2015 |
The endogenous tryptophan metabolite and NAD+ precursor quinolinic acid confers resistance of gliomas to oxidative stress F Sahm, I Oezen, CA Opitz, B Radlwimmer, A Von Deimling, T Ahrendt, ... Cancer research 73 (11), 3225-3234, 2013 | 180 | 2013 |
Immature mesenchymal stem cell-like pericytes as mediators of immunosuppression in human malignant glioma K Ochs, F Sahm, CA Opitz, TV Lanz, I Oezen, PO Couraud, ... Journal of neuroimmunology 265 (1-2), 106-116, 2013 | 104 | 2013 |
Dietary tryptophan links encephalogenicity of autoreactive T cells with gut microbial ecology JK Sonner, M Keil, M Falk-Paulsen, N Mishra, A Rehman, M Kramer, ... Nature communications 10 (1), 4877, 2019 | 79 | 2019 |
Myelin basic protein cleaves cell adhesion molecule L1 and promotes neuritogenesis and cell survival D Lutz, G Loers, R Kleene, I Oezen, H Kataria, N Katagihallimath, I Braren, ... Journal of Biological Chemistry 289 (19), 13503-13518, 2014 | 62 | 2014 |
Distribution and cellular localization of adrenoleukodystrophy protein in human tissues: implications for X-linked adrenoleukodystrophy R Höftberger, M Kunze, I Weinhofer, F Aboul-Enein, T Voigtländer, ... Neurobiology of disease 28 (2), 165-174, 2007 | 60 | 2007 |
Proximity ligation assay evaluates IDH1R132H presentation in gliomas L Bunse, T Schumacher, F Sahm, S Pusch, I Oezen, K Rauschenbach, ... The Journal of Clinical Investigation 125 (2), 593-606, 2015 | 59 | 2015 |
Targeting resistance against the MDM2 inhibitor RG7388 in glioblastoma cells by the MEK inhibitor trametinib A Berberich, T Kessler, CM Thomé, S Pusch, T Hielscher, F Sahm, ... Clinical Cancer Research 25 (1), 253-265, 2019 | 53 | 2019 |
Dermatan 4-O-sulfotransferase1 ablation accelerates peripheral nerve regeneration N Akyüz, S Rost, A Mehanna, S Bian, G Loers, I Oezen, B Mishra, ... Experimental neurology 247, 517-530, 2013 | 46 | 2013 |
Accumulation of very long-chain fatty acids does not affect mitochondrial function in adrenoleukodystrophy protein deficiency I Oezen, W Rossmanith, S Forss-Petter, S Kemp, T Voigtländer, ... Human molecular genetics 14 (9), 1127-1137, 2005 | 40 | 2005 |
Synovial fibroblasts selectively suppress Th1 cell responses through IDO1-mediated tryptophan catabolism LO Tykocinski, AM Lauffer, A Bohnen, NC Kaul, S Krienke, T Tretter, ... The Journal of Immunology 198 (8), 3109-3117, 2017 | 38 | 2017 |
General control non-derepressible 2 (GCN2) in T cells controls disease progression of autoimmune neuroinflammation M Keil, JK Sonner, TV Lanz, I Oezen, T Bunse, S Bittner, HV Meyer, ... Journal of Neuroimmunology 297, 117-126, 2016 | 26 | 2016 |
Identification of BAY-218, a potent and selective small-molecule AhR inhibitor, as a new modality to counteract tumor immunosuppression N Schmees, I Gutcher, U Roehn, H Irlbacher, D Stoeckigt, B Bader, ... Cancer Research 79 (13_Supplement), 4454-4454, 2019 | 13 | 2019 |
Blocking tumor-associated immune suppression with BAY-218, a novel, selective aryl hydrocarbon receptor (AhR) inhibitor I Gutcher, C Kober, L Roese, J Roewe, N Schmees, F Prinz, M Gorjanacz, ... Cancer Research 79 (13_Supplement), 1288-1288, 2019 | 13 | 2019 |
Targeting the aryl hydrocarbon receptor (AhR) with BAY 2416964: a selective small molecule inhibitor for cancer immunotherapy C Kober, J Roewe, N Schmees, L Roese, U Roehn, B Bader, D Stoeckigt, ... Journal for Immunotherapy of Cancer 11 (11), 2023 | 2 | 2023 |
In situ proximity ligation assay to evaluate presentation of a mutated CD4 epitope in human glioma tissue L Bunse, T Schumacher, F Sahm, S Pusch, I Oezen, A von Deimling, ... Journal of Neuroimmunology 275 (1), 35, 2014 | 1 | 2014 |
Dietary tryptophan is required for CNS infiltration of encephalitogenic T cells M Keil, M Paulsen, J Sonner, F Wanke, I Oezen, T Schumacher, JG Okun, ... Journal of neuroimmunology 275 (1), 156, 2014 | 1 | 2014 |
Pharmacological treatment based on gene redundancy: a novel therapeutic approach for X-linked adrenoleukodystrophy J Berger, S Forss-Petter, I Oezen, I Weinhofer Understanding and Treating of X-linked adrenoleukodystrophy: Present State …, 2005 | 1 | 2005 |