The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1 L Chantranupong, RL Wolfson, JM Orozco, RA Saxton, SM Scaria, ... Cell reports 9 (1), 1-8, 2014 | 452 | 2014 |
Highly multiplexed quantitative mass spectrometry analysis of ubiquitylomes CM Rose, M Isasa, A Ordureau, MA Prado, SA Beausoleil, ... Cell systems 3 (4), 395-403. e4, 2016 | 167 | 2016 |
Monoubiquitination of RPN10 regulates substrate recruitment to the proteasome M Isasa, EJ Katz, W Kim, V Yugo, S González, DS Kirkpatrick, ... Molecular cell 38 (5), 733-745, 2010 | 154 | 2010 |
PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival during hypoxia RS Banh, C Iorio, R Marcotte, Y Xu, D Cojocari, AA Rahman, J Pawling, ... Nature cell biology 18 (7), 803-813, 2016 | 114 | 2016 |
Ubiquitin signaling: extreme conservation as a source of diversity A Zuin, M Isasa, B Crosas Cells 3 (3), 690-701, 2014 | 78 | 2014 |
Proteomic analysis identifies ribosome reduction as an effective proteotoxic stress response A Guerra-Moreno, M Isasa, MK Bhanu, DP Waterman, VV Eapen, SP Gygi, ... Journal of Biological Chemistry 290 (50), 29695-29706, 2015 | 66 | 2015 |
A new map to understand deubiquitination EJ Katz, M Isasa, B Crosas Biochemical Society Transactions 38 (1), 21-28, 2010 | 62 | 2010 |
Multiplexed, proteome-wide protein expression profiling: yeast deubiquitylating enzyme knockout strains M Isasa, CM Rose, S Elsasser, J Navarrete-Perea, JA Paulo, DJ Finley, ... Journal of proteome research 14 (12), 5306-5317, 2015 | 57 | 2015 |
The methionine transamination pathway controls hepatic glucose metabolism through regulation of the GCN5 acetyltransferase and the PGC-1α transcriptional coactivator CDJ Tavares, K Sharabi, JE Dominy, Y Lee, M Isasa, JM Orozco, ... Journal of Biological Chemistry 291 (20), 10635-10645, 2016 | 42 | 2016 |
Rpn10 monoubiquitination orchestrates the association of the ubiquilin-type DSK2 receptor with the proteasome A Zuin, A Bichmann, M Isasa, P Puig-Sàrries, LM Díaz, B Crosas Biochemical Journal 472 (3), 353-365, 2015 | 27 | 2015 |
Targeted degradation of glucose transporters protects against arsenic toxicity M Jochem, L Ende, M Isasa, J Ang, H Schnell, A Guerra-Moreno, ... Molecular and Cellular Biology 39 (10), e00559-18, 2019 | 23 | 2019 |
Cuz1/Ynl155w, a zinc-dependent ubiquitin-binding protein, protects cells from metalloid-induced proteotoxicity J Hanna, D Waterman, M Isasa, S Elsasser, Y Shi, S Gygi, D Finley Journal of Biological Chemistry 289 (3), 1876-1885, 2014 | 23 | 2014 |
Abstract ND09: The discovery and characterization of CFT8634: A potent and selective degrader of BRD9 for the treatment of SMARCB1-perturbed cancers KL Jackson, RV Agafonov, MW Carlson, P Chaturvedi, D Cocozziello, ... Cancer Research 82 (12_Supplement), ND09-ND09, 2022 | 20 | 2022 |
Defective in mitotic arrest 1 (Dma1) ubiquitin ligase controls G1 cyclin degradation S Hernández-Ortega, S Bru, N Ricco, S Ramírez, N Casals, J Jiménez, ... Journal of Biological Chemistry 288 (7), 4704-4714, 2013 | 16 | 2013 |
Cold temperature induces the reprogramming of proteolytic pathways in yeast M Isasa, C Suñer, M Díaz, P Puig-Sàrries, A Zuin, A Bichman, SP Gygi, ... Journal of Biological Chemistry 291 (4), 1664-1675, 2016 | 13 | 2016 |
A method for determining the kinetics of small-molecule-induced ubiquitination EF Vieux, RV Agafonov, L Emerson, M Isasa, RW Deibler, JR Simard, ... SLAS DISCOVERY: Advancing the Science of Drug Discovery 26 (4), 547-559, 2021 | 11 | 2021 |
Quantitative multiplexed proteomics of Taenia solium cysts obtained from the skeletal muscle and central nervous system of pigs J Navarrete-Perea, M Isasa, JA Paulo, R Corral-Corral, J Flores-Bautista, ... PLoS Neglected Tropical Diseases 11 (9), e0005962, 2017 | 11 | 2017 |
Integration of multiple ubiquitin signals in proteasome regulation M Isasa, A Zuin, B Crosas Bioinformatics and Drug Discovery, 337-370, 2012 | 10 | 2012 |
Phosphorylation of RXRα mediates the effect of JNK to suppress hepatic FGF21 expression and promote metabolic syndrome S Vernia, A Lee, NJ Kennedy, MS Han, M Isasa, J Cavanagh-Kyros, ... Proceedings of the National Academy of Sciences 119 (44), e2210434119, 2022 | 7 | 2022 |
Iron deficiency and recovery in yeast: a quantitative proteomics approach J Navarrete-Perea, A Guerra-Moreno, J Van Vranken, M Isasa, JA Paulo, ... Journal of proteome research 20 (5), 2751-2761, 2021 | 5 | 2021 |