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Paolo Ambrosino
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Genotype–phenotype correlations in neonatal epilepsies caused by mutations in the voltage sensor of Kv7. 2 potassium channel subunits
F Miceli, MV Soldovieri, P Ambrosino, V Barrese, M Migliore, MR Cilio, ...
Proceedings of the National Academy of Sciences 110 (11), 4386-4391, 2013
1962013
Early-onset epileptic encephalopathy caused by gain-of-function mutations in the voltage sensor of Kv7. 2 and Kv7. 3 potassium channel subunits
F Miceli, MV Soldovieri, P Ambrosino, M De Maria, M Migliore, R Migliore, ...
Journal of Neuroscience 35 (9), 3782-3793, 2015
1802015
Activation and desensitization of trpv1 channels in sensory neurons by the peroxisome proliferator-activated receptor α agonist palmitoylethanolamide
P Ambrosino, MV Soldovieri, C Russo, M Taglialatela
British Journal of Pharmacology 168 (6), 1430-1444, 2013
142*2013
Novel KCNQ2 and KCNQ3 Mutations in a Large Cohort of Families with Benign Neonatal Epilepsy: First Evidence for an Altered Channel Regulation by Syntaxin‐1A
MV Soldovieri, N Boutry‐Kryza, M Milh, D Doummar, B Heron, E Bourel, ...
Human mutation 35 (3), 356-367, 2014
1192014
Effects of natural and synthetic isothiocyanate-based H2S-releasers against chemotherapy-induced neuropathic pain: Role of Kv7 potassium channels
LDC Mannelli, E Lucarini, L Micheli, I Mosca, P Ambrosino, MV Soldovieri, ...
Neuropharmacology 121, 49-59, 2017
1062017
The ever changing moods of calmodulin: how structural plasticity entails transductional adaptability
A Villarroel, M Taglialatela, G Bernardo-Seisdedos, A Alaimo, J Agirre, ...
Journal of molecular biology 426 (15), 2717-2735, 2014
1022014
Infantile spasms and encephalopathy without preceding neonatal seizures caused by KCNQ2 R198Q, a gain‐of‐function variant
JJ Millichap, F Miceli, M De Maria, C Keator, N Joshi, B Tran, ...
Epilepsia 58 (1), e10-e15, 2017
942017
The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of Kv7 channels
FA Iannotti, C Silvestri, E Mazzarella, A Martella, D Calvigioni, F Piscitelli, ...
Proceedings of the National Academy of Sciences 111 (24), E2472-E2481, 2014
932014
Characterization of two de novo KCNT1 mutations in children with malignant migrating partial seizures in infancy
F Rizzo, P Ambrosino, A Guacci, M Chetta, G Marchese, T Rocco, ...
Molecular and Cellular Neuroscience 72, 54-63, 2016
832016
Expression and function of Kv7. 4 channels in rat cardiac mitochondria: possible targets for cardioprotection
L Testai, V Barrese, MV Soldovieri, P Ambrosino, A Martelli, I Vinciguerra, ...
Cardiovascular research 110 (1), 40-50, 2016
812016
Epileptic channelopathies caused by neuronal Kv7 (KCNQ) channel dysfunction
P Nappi, F Miceli, MV Soldovieri, P Ambrosino, V Barrese, M Taglialatela
Pflügers Archiv-European Journal of Physiology 472, 881-898, 2020
732020
Neuronal potassium channel openers in the management of epilepsy: role and potential of retigabine
V Barrese, F Miceli, MV Soldovieri, P Ambrosino, FA Iannotti, MR Cilio, ...
Clinical pharmacology: advances and applications, 225-236, 2010
682010
Early treatment with quinidine in 2 patients with epilepsy of infancy with migrating focal seizures (EIMFS) due to gain-of-function KCNT1 mutations: functional studies …
R Dilena, JC DiFrancesco, MV Soldovieri, A Giacobbe, P Ambrosino, ...
Neurotherapeutics 15 (4), 1112-1126, 2018
552018
Epilepsy-causing mutations in Kv7. 2 C-terminus affect binding and functional modulation by calmodulin
P Ambrosino, A Alaimo, S Bartollino, L Manocchio, M De Maria, I Mosca, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1852 (9 …, 2015
552015
Neurounina-1, a novel compound that increases Na+/Ca2+ exchanger activity, effectively protects against stroke damage
P Molinaro, M Cantile, O Cuomo, A Secondo, A Pannaccione, ...
Molecular Pharmacology 83 (1), 142-156, 2013
512013
De novo gain‐of‐function variants in KCNT2 as a novel cause of developmental and epileptic encephalopathy
P Ambrosino, MV Soldovieri, T Bast, PD Turnpenny, S Uhrig, S Biskup, ...
Annals of neurology 83 (6), 1198-1204, 2018
492018
T-type channel blocking properties and antiabsence activity of two imidazo [1, 2-b] pyridazine derivatives structurally related to indomethacin
MG Rimoli, E Russo, M Cataldi, R Citraro, P Ambrosino, D Melisi, ...
Neuropharmacology 56 (3), 637-646, 2009
472009
Pharmacological targeting of neuronal Kv7. 2/3 channels: a focus on chemotypes and receptor sites
F Miceli, MV Soldovieri, P Ambrosino, L Manocchio, I Mosca, ...
Current medicinal chemistry 25 (23), 2637-2660, 2018
462018
Tryptamine-based derivatives as transient receptor potential melastatin type 8 (TRPM8) channel modulators
A Bertamino, C Ostacolo, P Ambrosino, S Musella, V Di Sarno, T Ciaglia, ...
Journal of Medicinal Chemistry 59 (5), 2179-2191, 2016
462016
Early-onset epileptic encephalopathy caused by a reduced sensitivity of Kv7. 2 potassium channels to phosphatidylinositol 4, 5-bisphosphate
MV Soldovieri, P Ambrosino, I Mosca, M De Maria, E Moretto, F Miceli, ...
Scientific reports 6 (1), 38167, 2016
452016
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