Michele Vendruscolo
Michele Vendruscolo
Professor of Biophysics, University of Cambridge
Verified email at cam.ac.uk - Homepage
Cited by
Cited by
The amyloid state and its association with protein misfolding diseases
TPJ Knowles, M Vendruscolo, CM Dobson
Nature reviews Molecular cell biology 15 (6), 384-396, 2014
An analytical solution to the kinetics of breakable filament assembly
TPJ Knowles, CA Waudby, GL Devlin, SIA Cohen, A Aguzzi, ...
Science 326 (5959), 1533-1537, 2009
Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism
SIA Cohen, S Linse, LM Luheshi, E Hellstrand, DA White, L Rajah, ...
Proceedings of the National Academy of Sciences 110 (24), 9758-9763, 2013
Simultaneous determination of protein structure and dynamics
K Lindorff-Larsen, RB Best, MA DePristo, CM Dobson, M Vendruscolo
Nature 433 (7022), 128-132, 2005
Role of intermolecular forces in defining material properties of protein nanofibrils
TP Knowles, AW Fitzpatrick, S Meehan, HR Mott, M Vendruscolo, ...
Science 318 (5858), 1900-1903, 2007
Prediction of “aggregation-prone” and “aggregation-susceptible” regions in proteins associated with neurodegenerative diseases
AP Pawar, KF Dubay, J Zurdo, F Chiti, M Vendruscolo, CM Dobson
Journal of molecular biology 350 (2), 379-392, 2005
Mapping long-range interactions in α-synuclein using spin-label NMR and ensemble molecular dynamics simulations
MM Dedmon, K Lindorff-Larsen, J Christodoulou, M Vendruscolo, ...
Journal of the American Chemical Society 127 (2), 476-477, 2005
Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions
H Olzscha, SM Schermann, AC Woerner, S Pinkert, MH Hecht, ...
Cell 144 (1), 67-78, 2011
Protein structure determination from NMR chemical shifts
A Cavalli, X Salvatella, CM Dobson, M Vendruscolo
Proceedings of the National Academy of Sciences 104 (23), 9615-9620, 2007
Low-populated folding intermediates of Fyn SH3 characterized by relaxation dispersion NMR
DM Korzhnev, X Salvatella, M Vendruscolo, AA Di Nardo, AR Davidson, ...
Nature 430 (6999), 586-590, 2004
Three key residues form a critical contact network in a protein folding transition state
M Vendruscolo, E Paci, CM Dobson, M Karplus
Nature 409 (6820), 641-645, 2001
Prediction of aggregation-prone regions in structured proteins
GG Tartaglia, AP Pawar, S Campioni, CM Dobson, F Chiti, M Vendruscolo
Journal of molecular biology 380 (2), 425-436, 2008
Atomic structure and hierarchical assembly of a cross-β amyloid fibril
AWP Fitzpatrick, GT Debelouchina, MJ Bayro, DK Clare, MA Caporini, ...
Proceedings of the National Academy of Sciences 110 (14), 5468-5473, 2013
Small-world view of the amino acids that play a key role in protein folding
M Vendruscolo, NV Dokholyan, E Paci, M Karplus
Physical Review E 65 (6), 061910, 2002
ALS/FTD mutation-induced phase transition of FUS liquid droplets and reversible hydrogels into irreversible hydrogels impairs RNP granule function
T Murakami, S Qamar, JQ Lin, GSK Schierle, E Rees, A Miyashita, ...
Neuron 88 (4), 678-690, 2015
Solution conditions determine the relative importance of nucleation and growth processes in α-synuclein aggregation
AK Buell, C Galvagnion, R Gaspar, E Sparr, M Vendruscolo, TPJ Knowles, ...
Proceedings of the National Academy of Sciences 111 (21), 7671-7676, 2014
Metastability of native proteins and the phenomenon of amyloid formation
AJ Baldwin, TPJ Knowles, GG Tartaglia, AW Fitzpatrick, GL Devlin, ...
Journal of the American Chemical Society 133 (36), 14160-14163, 2011
From macroscopic measurements to microscopic mechanisms of protein aggregation
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
Journal of molecular biology 421 (2-3), 160-171, 2012
Widespread proteome remodeling and aggregation in aging C. elegans
DM Walther, P Kasturi, M Zheng, S Pinkert, G Vecchi, P Ciryam, ...
Cell 161 (4), 919-932, 2015
Prediction of the absolute aggregation rates of amyloidogenic polypeptide chains
KF DuBay, AP Pawar, F Chiti, J Zurdo, CM Dobson, M Vendruscolo
Journal of molecular biology 341 (5), 1317-1326, 2004
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