| The amyloid state and its association with protein misfolding diseases TPJ Knowles, M Vendruscolo, CM Dobson Nature reviews Molecular cell biology 15 (6), 384-396, 2014 | 1784 | 2014 |
| Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism SIA Cohen, S Linse, LM Luheshi, E Hellstrand, DA White, L Rajah, ... Proceedings of the National Academy of Sciences 110 (24), 9758-9763, 2013 | 1003 | 2013 |
| An analytical solution to the kinetics of breakable filament assembly TPJ Knowles, CA Waudby, GL Devlin, SIA Cohen, A Aguzzi, ... Science 326 (5959), 1533-1537, 2009 | 959 | 2009 |
| Role of intermolecular forces in defining material properties of protein nanofibrils TP Knowles, AW Fitzpatrick, S Meehan, HR Mott, M Vendruscolo, ... science 318 (5858), 1900-1903, 2007 | 722 | 2007 |
| Simultaneous determination of protein structure and dynamics K Lindorff-Larsen, RB Best, MA DePristo, CM Dobson, M Vendruscolo Nature 433 (7022), 128-132, 2005 | 718 | 2005 |
| Mapping long-range interactions in α-synuclein using spin-label NMR and ensemble molecular dynamics simulations MM Dedmon, K Lindorff-Larsen, J Christodoulou, M Vendruscolo, ... Journal of the American Chemical Society 127 (2), 476-477, 2005 | 662 | 2005 |
| Prediction of “aggregation-prone” and “aggregation-susceptible” regions in proteins associated with neurodegenerative diseases AP Pawar, KF Dubay, J Zurdo, F Chiti, M Vendruscolo, CM Dobson Journal of molecular biology 350 (2), 379-392, 2005 | 655 | 2005 |
| Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions H Olzscha, SM Schermann, AC Woerner, S Pinkert, MH Hecht, ... Cell 144 (1), 67-78, 2011 | 623 | 2011 |
| Protein structure determination from NMR chemical shifts A Cavalli, X Salvatella, CM Dobson, M Vendruscolo Proceedings of the National Academy of Sciences 104 (23), 9615-9620, 2007 | 541 | 2007 |
| ALS/FTD mutation-induced phase transition of FUS liquid droplets and reversible hydrogels into irreversible hydrogels impairs RNP granule function T Murakami, S Qamar, JQ Lin, GSK Schierle, E Rees, A Miyashita, ... Neuron 88 (4), 678-690, 2015 | 534 | 2015 |
| Low-populated folding intermediates of Fyn SH3 characterized by relaxation dispersion NMR DM Korzhnev, X Salvatella, M Vendruscolo, AA Di Nardo, AR Davidson, ... Nature 430 (6999), 586-590, 2004 | 501 | 2004 |
| Atomic structure and hierarchical assembly of a cross-β amyloid fibril AWP Fitzpatrick, GT Debelouchina, MJ Bayro, DK Clare, MA Caporini, ... Proceedings of the National Academy of Sciences 110 (14), 5468-5473, 2013 | 493 | 2013 |
| Parmbsc1: a refined force field for DNA simulations I Ivani, PD Dans, A Noy, A Pérez, I Faustino, A Hospital, J Walther, ... Nature methods 13 (1), 55-58, 2016 | 474 | 2016 |
| Three key residues form a critical contact network in a protein folding transition state M Vendruscolo, E Paci, CM Dobson, M Karplus Nature 409 (6820), 641-645, 2001 | 466 | 2001 |
| Solution conditions determine the relative importance of nucleation and growth processes in α-synuclein aggregation AK Buell, C Galvagnion, R Gaspar, E Sparr, M Vendruscolo, TPJ Knowles, ... Proceedings of the National Academy of Sciences 111 (21), 7671-7676, 2014 | 465 | 2014 |
| Prediction of aggregation-prone regions in structured proteins GG Tartaglia, AP Pawar, S Campioni, CM Dobson, F Chiti, M Vendruscolo Journal of molecular biology 380 (2), 425-436, 2008 | 460 | 2008 |
| Widespread proteome remodeling and aggregation in aging C. elegans DM Walther, P Kasturi, M Zheng, S Pinkert, G Vecchi, P Ciryam, ... Cell 161 (4), 919-932, 2015 | 427 | 2015 |
| Small-world view of the amino acids that play a key role in protein folding M Vendruscolo, NV Dokholyan, E Paci, M Karplus Physical Review E 65 (6), 061910, 2002 | 424 | 2002 |
| Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation C Galvagnion, AK Buell, G Meisl, TCT Michaels, M Vendruscolo, ... Nature chemical biology 11 (3), 229-234, 2015 | 406 | 2015 |
| From macroscopic measurements to microscopic mechanisms of protein aggregation SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles Journal of molecular biology 421 (2-3), 160-171, 2012 | 400 | 2012 |
