| ChEMBL: towards direct deposition of bioassay data D Mendez, A Gaulton, AP Bento, J Chambers, M De Veij, E Félix, ... Nucleic acids research 47 (D1), D930-D940, 2019 | 1554 | 2019 |
| Synthesis and structure–activity-relationship studies of thiazolidinediones as antiplasmodial inhibitors of the Plasmodium falciparum cysteine protease falcipain-2 RK Sharma, Y Younis, G Mugumbate, M Njoroge, J Gut, PJ Rosenthal, ... European journal of medicinal chemistry 90, 507-518, 2015 | 56 | 2015 |
| The relationship between target-class and the physicochemical properties of antibacterial drugs G Mugumbate, JP Overington Bioorganic & medicinal chemistry 23 (16), 5218-5224, 2015 | 53 | 2015 |
| Mycobacterial Dihydrofolate Reductase Inhibitors Identified Using Chemogenomic Methods and In Vitro Validation G Mugumbate, KA Abrahams, JAG Cox, G Papadatos, G Van Westen, ... PloS one 10 (3), e0121492, 2015 | 53 | 2015 |
| Release of 50 new, drug-like compounds and their computational target predictions for open source anti-tubercular drug discovery MJ Rebollo-Lopez, J Lelièvre, D Alvarez-Gomez, J Castro-Pichel, ... PloS one 10 (12), e0142293, 2015 | 46 | 2015 |
| 3-Hydroxyisoflavanones from the stem bark of Dalbergia melanoxylon: Isolation, antimycobacterial evaluation and molecular docking studies P Mutai, M Heydenreich, G Thoithi, G Mugumbate, K Chibale, A Yenesew Phytochemistry Letters 6 (4), 671-675, 2013 | 35 | 2013 |
| Novel inhibitors of Mycobacterium tuberculosis GuaB2 identified by a target based high-throughput phenotypic screen JAG Cox, G Mugumbate, LVG Del Peral, M Jankute, KA Abrahams, ... Scientific reports 6 (1), 38986, 2016 | 30 | 2016 |
| Tetrazole-based deoxyamodiaquines: synthesis, ADME/PK profiling and pharmacological evaluation as potential antimalarial agents M Tukulula, M Njoroge, GC Mugumbate, J Gut, PJ Rosenthal, S Barteau, ... Bioorganic & medicinal chemistry 21 (17), 4904-4913, 2013 | 30 | 2013 |
| Target Identification of Mycobacterium tuberculosis Phenotypic Hits Using a Concerted Chemogenomic, Biophysical, and Structural Approach G Mugumbate, V Mendes, M Blaszczyk, M Sabbah, G Papadatos, ... Frontiers in pharmacology 8, 681, 2017 | 27 | 2017 |
| In silico comparison of antimycobacterial natural products with known antituberculosis drugs M Espinoza-Moraga, NM Njuguna, G Mugumbate, J Caballero, K Chibale Journal of chemical information and modeling 53 (3), 649-660, 2013 | 25 | 2013 |
| Synthesis and in vitro and in vivo pharmacological evaluation of new 4-aminoquinoline-based compounds M Tukulula, M Njoroge, ET Abay, GC Mugumbate, L Wiesner, D Taylor, ... ACS medicinal chemistry letters 4 (12), 1198-1202, 2013 | 22 | 2013 |
| Novel anti-Plasmodial hits identified by virtual screening of the ZINC database G Mugumbate, AS Newton, PJ Rosenthal, J Gut, R Moreira, K Chibale, ... Journal of computer-aided molecular design 27, 859-871, 2013 | 22 | 2013 |
| Anopheles gambiae, Anoga-HrTH hormone, free and bound structure–A nuclear magnetic resonance experiment G Mugumbate, GE Jackson, D van der Spoel, KE Kövér, L Szilágyi Peptides 41, 94-100, 2013 | 19 | 2013 |
| Open conformation of adipokinetic hormone receptor from the malaria mosquito facilitates hormone binding G Mugumbate, GE Jackson, D Van der Spoel Peptides 32 (3), 553-559, 2011 | 18 | 2011 |
| Natural products: a potential source of malaria transmission blocking drugs? P Moyo, G Mugumbate, JN Eloff, AI Louw, VJ Maharaj, LM Birkholtz Pharmaceuticals 13 (9), 251, 2020 | 17 | 2020 |
| Advances in schistosomiasis drug discovery based on natural products. FL Mtemeli, J Ndlovu, G Mugumbate, T Makwikwi, R Shoko All Life 15 (1), 608-623, 2022 | 12 | 2022 |
| Structural studies of adipokinetic hormones in water and DPC micelle solution using NMR distance restrained molecular dynamics GE Jackson, R Gamieldien, G Mugumbate, G Gäde Peptides 53, 270-277, 2014 | 12 | 2014 |
| Strategies and opportunities for promoting bioinformatics in Zimbabwe R Shoko, J Manasa, M Maphosa, J Mbanga, R Mudziwapasi, ... PLoS Computational Biology 14 (11), e1006480, 2018 | 11 | 2018 |
| Application of Computational Methods in Understanding Mutations in Mycobacterium tuberculosis Drug Resistance G Mugumbate, B Nyathi, A Zindoga, G Munyuki Frontiers in Molecular Biosciences 8, 643849, 2021 | 9 | 2021 |
| TIBLE: a web-based, freely accessible resource for small-molecule binding data for mycobacterial species S Malhotra, G Mugumbate, TL Blundell, AP Higueruelo Database 2017, bax041, 2017 | 7 | 2017 |
John P. OveringtonChief Data Officer, ExscientiaEmail verificata su exscientia.co.uk
