| Modulation of the innate immune response by targeting toll-like receptors: a perspective on their agonists and antagonists S Federico, L Pozzetti, A Papa, G Carullo, S Gemma, S Butini, ... Journal of Medicinal Chemistry 63 (22), 13466-13513, 2020 | 78 | 2020 |
| Structure-based discovery of the first non-covalent inhibitors of Leishmania major tryparedoxin peroxidase by high throughput docking M Brindisi, S Brogi, N Relitti, A Vallone, S Butini, S Gemma, E Novellino, ... Scientific reports 5 (1), 9705, 2015 | 75 | 2015 |
| Autophagy modulators for the treatment of oral and esophageal squamous cell carcinomas T Khan, N Relitti, M Brindisi, S Magnano, D Zisterer, S Gemma, S Butini, ... Medicinal Research Reviews 40 (3), 1002-1060, 2020 | 71 | 2020 |
| Telomerase-based cancer therapeutics: a review on their clinical trials N Relitti, AP Saraswati, S Federico, T Khan, M Brindisi, D Zisterer, S Brogi, ... Current Topics in Medicinal Chemistry 20 (6), 433-457, 2020 | 42 | 2020 |
| Raising the bar in anticancer therapy: recent advances in, and perspectives on, telomerase inhibitors AP Saraswati, N Relitti, M Brindisi, S Gemma, D Zisterer, S Butini, ... Drug Discovery Today 24 (7), 1370-1388, 2019 | 37 | 2019 |
| Harnessing the role of HDAC6 in idiopathic pulmonary fibrosis: design, synthesis, structural analysis, and biological evaluation of potent inhibitors G Campiani, C Cavella, JD Osko, M Brindisi, N Relitti, S Brogi, ... Journal of medicinal chemistry 64 (14), 9960-9988, 2021 | 30 | 2021 |
| Novel quinolone-based potent and selective HDAC6 inhibitors: Synthesis, molecular modeling studies and biological investigation N Relitti, AP Saraswati, G Chemi, M Brindisi, S Brogi, D Herp, ... European Journal of Medicinal Chemistry 212, 112998, 2021 | 30 | 2021 |
| Spiroindoline-capped selective HDAC6 inhibitors: design, synthesis, structural analysis, and biological evaluation AP Saraswati, N Relitti, M Brindisi, JD Osko, G Chemi, S Federico, A Grillo, ... ACS Medicinal Chemistry Letters 11 (11), 2268-2276, 2020 | 30 | 2020 |
| Screening and Phenotypical Characterization of Schistosoma mansoni Histone Deacetylase 8 (SmHDAC8) Inhibitors as Multistage Antischistosomal Agents F Saccoccia, M Brindisi, R Gimmelli, N Relitti, A Guidi, AP Saraswati, ... ACS Infectious Diseases 6 (1), 100-113, 2019 | 30 | 2019 |
| Enantioselective Synthesis of Thailanstatin A Methyl Ester and Evaluation of in Vitro Splicing Inhibition AK Ghosh, AM Veitschegger, S Nie, N Relitti, AJ MacRae, MS Jurica The Journal of organic chemistry 83 (9), 5187-5198, 2018 | 27 | 2018 |
| Enantioselective synthesis of a cyclopropane derivative of spliceostatin A and evaluation of bioactivity AK Ghosh, GC Reddy, S Kovela, N Relitti, VK Urabe, BE Prichard, ... Organic letters 20 (22), 7293-7297, 2018 | 21 | 2018 |
| Novel peptidomimetics as BACE-1 inhibitors: synthesis, molecular modeling, and biological studies S Butini, E Gabellieri, M Brindisi, A Casagni, E Guarino, PB Huleatt, ... Bioorganic & medicinal chemistry letters 23 (1), 85-89, 2013 | 17 | 2013 |
| Development of novel multipotent compounds modulating endocannabinoid and dopaminergic systems A Grillo, G Chemi, S Brogi, M Brindisi, N Relitti, F Fezza, D Fazio, ... European Journal of Medicinal Chemistry 183, 111674, 2019 | 15 | 2019 |
| Bridged bicyclic 2, 3-dioxabicyclo [3.3. 1] nonanes as antiplasmodial agents: Synthesis, structure-activity relationships and studies on their biomimetic reaction with Fe (II) S D'Alessandro, G Alfano, L Di Cerbo, S Brogi, G Chemi, N Relitti, ... Bioorganic Chemistry 89, 103020, 2019 | 15 | 2019 |
| Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability S Federico, T Khan, A Fontana, S Brogi, R Benedetti, F Sarno, G Carullo, ... European Journal of Medicinal Chemistry 238, 114409, 2022 | 13 | 2022 |
| Selective fatty acid amide hydrolase inhibitors as potential novel antiepileptic agents A Grillo, F Fezza, G Chemi, R Colangeli, S Brogi, D Fazio, S Federico, ... ACS Chemical Neuroscience 12 (9), 1716-1736, 2021 | 13 | 2021 |
| Retinitis pigmentosa and retinal degenerations: Deciphering pathways and targets for drug discovery and development G Carullo, S Federico, N Relitti, S Gemma, S Butini, G Campiani ACS chemical neuroscience 11 (15), 2173-2191, 2020 | 13 | 2020 |
| A light in the dark: state of the art and perspectives in optogenetics and optopharmacology for restoring vision G Chemi, M Brindisi, S Brogi, N Relitti, S Butini, S Gemma, G Campiani Future Medicinal Chemistry 11 (5), 463-487, 2019 | 8 | 2019 |
| Synthesis and biological evaluation of benzhydryl-based antiplasmodial agents possessing Plasmodium falciparum chloroquine resistance transporter (PfCRT) inhibitory activity N Relitti, S Federico, L Pozzetti, S Butini, S Lamponi, D Taramelli, ... European Journal of Medicinal Chemistry 215, 113227, 2021 | 6 | 2021 |
| A Jocic-type approach for a practical and scalable synthesis of pyrrolonaphthoxazepine (PNOX)-based potent proapoptotic agents S Federico, T Khan, N Relitti, G Chemi, M Brindisi, S Brogi, E Novellino, ... Tetrahedron letters 59 (51), 4466-4470, 2018 | 6 | 2018 |
