Giorgio Seano
Giorgio Seano
Tumor Microenvironment Lab, Institut Curie (Paris)
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Semaphorin 3A is an endogenous angiogenesis inhibitor that blocks tumor growth and normalizes tumor vasculature in transgenic mouse models
F Maione, F Molla, C Meda, R Latini, L Zentilin, M Giacca, G Seano, ...
The Journal of clinical investigation 119 (11), 3356-3372, 2009
Ang-2/VEGF bispecific antibody reprograms macrophages and resident microglia to anti-tumor phenotype and prolongs glioblastoma survival
J Kloepper, L Riedemann, Z Amoozgar, G Seano, K Susek, V Yu, ...
Proceedings of the National Academy of Sciences 113 (16), 4476-4481, 2016
Dual inhibition of Ang-2 and VEGF receptors normalizes tumor vasculature and prolongs survival in glioblastoma by altering macrophages
TE Peterson, ND Kirkpatrick, Y Huang, CT Farrar, KA Marijt, J Kloepper, ...
Proceedings of the National Academy of Sciences 113 (16), 4470-4475, 2016
Role of vascular density and normalization in response to neoadjuvant bevacizumab and chemotherapy in breast cancer patients
SM Tolaney, Y Boucher, DG Duda, JD Martin, G Seano, M Ancukiewicz, ...
Proceedings of the National Academy of Sciences 112 (46), 14325-14330, 2015
Anti-vascular endothelial growth factor treatment normalizes tuberculosis granuloma vasculature and improves small molecule delivery
M Datta, LE Via, WS Kamoun, C Liu, W Chen, G Seano, DM Weiner, ...
Proceedings of the National Academy of Sciences 112 (6), 1827-1832, 2015
Solid stress and elastic energy as measures of tumour mechanopathology
HT Nia, H Liu, G Seano, M Datta, D Jones, N Rahbari, J Incio, ...
Nature biomedical engineering 1 (1), 1-11, 2016
Lymph node metastases can invade local blood vessels, exit the node, and colonize distant organs in mice
ER Pereira, D Kedrin, G Seano, O Gautier, EFJ Meijer, D Jones, SM Chin, ...
Science 359 (6382), 1403-1407, 2018
Endothelial podosome rosettes regulate vascular branching in tumour angiogenesis
G Seano, G Chiaverina, PA Gagliardi, L Di Blasio, A Puliafito, C Bouvard, ...
Nature cell biology 16 (10), 931-941, 2014
The miR-126 regulates angiopoietin-1 signaling and vessel maturation by targeting p85β
R Sessa, G Seano, L di Blasio, PA Gagliardi, C Isella, E Medico, F Cotelli, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1823 (10), 1925-1935, 2012
Blockade of MMP14 activity in murine breast carcinomas: implications for macrophages, vessels, and radiotherapy
EI Ager, SV Kozin, ND Kirkpatrick, G Seano, DP Kodack, V Askoxylakis, ...
JNCI: Journal of the National Cancer Institute 107 (4), 2015
Modeling human tumor angiogenesis in a three-dimensional culture system
G Seano, G Chiaverina, PA Gagliardi, L Di Blasio, R Sessa, F Bussolino, ...
Blood, The Journal of the American Society of Hematology 121 (21), e129-e137, 2013
Increased expression of α6 integrin in endothelial cells unveils a proangiogenic role for basement membrane
L Primo, G Seano, C Roca, F Maione, PA Gagliardi, R Sessa, M Martinelli, ...
Cancer research 70 (14), 5759-5769, 2010
3-phosphoinositide-dependent kinase 1 controls breast tumor growth in a kinase-dependent but Akt-independent manner
PA Gagliardi, L di Blasio, F Orso, G Seano, R Sessa, D Taverna, ...
Neoplasia (New York, NY) 14 (8), 719, 2012
A glial signature and Wnt7 signaling regulate glioma-vascular interactions and tumor microenvironment
A Griveau, G Seano, SJ Shelton, R Kupp, A Jahangiri, K Obernier, ...
Cancer Cell 33 (5), 874-889. e7, 2018
Liver X receptor activation reduces angiogenesis by impairing lipid raft localization and signaling of vascular endothelial growth factor receptor-2
A Noghero, A Perino, G Seano, E Saglio, GL Sasso, F Veglio, L Primo, ...
Arteriosclerosis, thrombosis, and vascular biology 32 (9), 2280-2288, 2012
Preclinical efficacy of ado-trastuzumab emtansine in the brain microenvironment
V Askoxylakis, GB Ferraro, DP Kodack, M Badeaux, RC Shankaraiah, ...
Journal of the National Cancer Institute 108 (2), djv313, 2016
Normalizing function of tumor vessels: progress, opportunities, and challenges
JD Martin, G Seano, RK Jain
Annual review of physiology, 2019
Podosomes and invadopodia: tools to breach vascular basement membrane
G Seano, L Primo
Cell cycle 14 (9), 1370-1374, 2015
Unraveling the influence of endothelial cell density on VEGF-A signaling
L Napione, S Pavan, A Veglio, A Picco, G Boffetta, A Celani, G Seano, ...
Blood, The Journal of the American Society of Hematology 119 (23), 5599-5607, 2012
PDK1-mediated activation of MRCKα regulates directional cell migration and lamellipodia retraction
PA Gagliardi, L Di Blasio, A Puliafito, G Seano, R Sessa, F Chianale, ...
Journal of Cell Biology 206 (3), 415-434, 2014
Il sistema al momento non pu eseguire l'operazione. Riprova pi tardi.
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