P21 and p27: roles in carcinogenesis and drug resistance AM Abukhdeir, BH Park Expert reviews in molecular medicine 10, e19, 2008 | 542 | 2008 |
The multiple myeloma–associated MMSET gene contributes to cellular adhesion, clonogenic growth, and tumorigenicity J Lauring, AM Abukhdeir, H Konishi, JP Garay, JP Gustin, Q Wang, ... Blood, The Journal of the American Society of Hematology 111 (2), 856-864, 2008 | 210 | 2008 |
Mutation of a single allele of the cancer susceptibility gene BRCA1 leads to genomic instability in human breast epithelial cells H Konishi, M Mohseni, A Tamaki, JP Garay, S Croessmann, S Karnan, ... Proceedings of the National Academy of Sciences 108 (43), 17773-17778, 2011 | 207 | 2011 |
Knockin of mutant PIK3CA activates multiple oncogenic pathways JP Gustin, B Karakas, MB Weiss, AM Abukhdeir, J Lauring, JP Garay, ... Proceedings of the National Academy of Sciences 106 (8), 2835-2840, 2009 | 183 | 2009 |
Tamoxifen-stimulated growth of breast cancer due to p21 loss AM Abukhdeir, MI Vitolo, P Argani, AM De Marzo, B Karakas, H Konishi, ... Proceedings of the National Academy of Sciences 105 (1), 288-293, 2008 | 107 | 2008 |
Knock-in of Mutant K-ras in Nontumorigenic Human Epithelial Cells as a New Model for Studying K-ras–Mediated Transformation H Konishi, B Karakas, AM Abukhdeir, J Lauring, JP Gustin, JP Garay, ... Cancer research 67 (18), 8460-8467, 2007 | 101 | 2007 |
Shared TP53 gene mutation in morphologically and phenotypically distinct concurrent primary small cell neuroendocrine carcinoma and adenocarcinoma of the prostate DE Hansel, M Nakayama, J Luo, AM Abukhdeir, BH Park, CJ Bieberich, ... The Prostate 69 (6), 603-609, 2009 | 99 | 2009 |
The growth response to androgen receptor signaling in ERα-negative human breast cells is dependent on p21 and mediated by MAPK activation JP Garay, B Karakas, AM Abukhdeir, DP Cosgrove, JP Gustin, MJ Higgins, ... Breast Cancer Research 14, 1-17, 2012 | 91 | 2012 |
MACROD2 overexpression mediates estrogen independent growth and tamoxifen resistance in breast cancers M Mohseni, J Cidado, S Croessmann, K Cravero, A Cimino-Mathews, ... Proceedings of the National Academy of Sciences 111 (49), 17606-17611, 2014 | 78 | 2014 |
Knock in of the AKT1 E17K mutation in human breast epithelial cells does not recapitulate oncogenic PIK3CA mutations J Lauring, DP Cosgrove, S Fontana, JP Gustin, H Konishi, AM Abukhdeir, ... Oncogene 29 (16), 2337-2345, 2010 | 59 | 2010 |
Overexpression of lipid metabolism genes and PBX1 in the contralateral breasts of women with estrogen receptor‐negative breast cancer J Wang, A Shidfar, D Ivancic, M Ranjan, L Liu, MR Choi, V Parimi, ... International journal of cancer 140 (11), 2484-2497, 2017 | 51 | 2017 |
Single copies of mutant KRAS and mutant PIK3CA cooperate in immortalized human epithelial cells to induce tumor formation GM Wang, HY Wong, H Konishi, BG Blair, AM Abukhdeir, JP Gustin, ... Cancer research 73 (11), 3248-3261, 2013 | 46 | 2013 |
P21 gene knock down does not identify genetic effectors seen with gene knock out B Karakas, AT Weeraratna, AM Abukhdeir, H Konishi, JP Gustin, MI Vitolo, ... Cancer biology & therapy 6 (7), 1025-1030, 2007 | 34 | 2007 |
Physiologic estrogen receptor alpha signaling in non-tumorigenic human mammary epithelial cells AM Abukhdeir, BG Blair, K Brenner, B Karakas, H Konishi, J Lim, ... Breast cancer research and treatment 99 (1), 23-33, 2006 | 30 | 2006 |
FDA approval summary: pertuzumab, trastuzumab, and hyaluronidase–zzxf injection for subcutaneous use in patients with HER2-positive breast cancer JJ Gao, CL Osgood, Y Gong, H Zhang, EW Bloomquist, X Jiang, J Qiu, ... Clinical Cancer Research 27 (8), 2126-2129, 2021 | 28 | 2021 |
A PCR-based high-throughput screen with multiround sample pooling: application to somatic cell gene targeting H Konishi, J Lauring, JP Garay, B Karakas, AM Abukhdeir, JP Gustin, ... Nature protocols 2 (11), 2865-2874, 2007 | 28 | 2007 |
KRAS mutation and epithelial–macrophage interplay in pancreatic neoplastic transformation F Bishehsari, L Zhang, U Barlass, NZ Preite, S Turturro, MS Najor, ... International journal of cancer 143 (8), 1994-2007, 2018 | 27 | 2018 |
Mutations in PIK3CA sensitize breast cancer cells to physiologic levels of aspirin SB Turturro, MS Najor, CE Ruby, MA Cobleigh, AM Abukhdeir Breast Cancer Research and Treatment 156, 33-43, 2016 | 27 | 2016 |
Interleukin-1 alpha mediates the growth proliferative effects of transforming growth factor-beta in p21 null MCF-10A human mammary epithelial cells B Karakas, A Weeraratna, A Abukhdeir, BG Blair, H Konishi, S Arena, ... Oncogene 25 (40), 5561-5569, 2006 | 27 | 2006 |
Competition between lithium and magnesium ions for the G-protein transducin in the guanosine 5′-diphosphate bound conformation C Srinivasan, J Toon, L Amari, AM Abukhdeir, H Hamm, CFGC Geraldes, ... Journal of inorganic biochemistry 98 (5), 691-701, 2004 | 24 | 2004 |