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Agnes Leffler
Agnes Leffler
Senior Research Scientist, RIA iMed, AstraZeneca
Email verificata su astrazeneca.com
Titolo
Citata da
Citata da
Anno
Benzoxazepines Achieve Potent Suppression of IL‐17 Release in Human T‐Helper 17 (TH17) Cells through an Induced‐Fit Binding Mode to the Nuclear …
RI Olsson, Y Xue, S von Berg, A Aagaard, J McPheat, EL Hansson, ...
ChemMedChem 11 (2), 207-216, 2016
602016
Characterization of species-related differences in the pharmacology of tachykinin NK receptors 1, 2 and 3
A Leffler, I Ahlstedt, S Engberg, A Svensson, M Billger, L Öberg, ...
Biochemical pharmacology 77 (9), 1522-1530, 2009
412009
Potent and orally bioavailable inverse agonists of RORγt resulting from structure-based design
F Narjes, Y Xue, S von Berg, J Malmberg, A Llinas, RI Olsson, J Jirholt, ...
Journal of Medicinal Chemistry 61 (17), 7796-7813, 2018
312018
Molecular cloning, mutations and effects of NK1 receptor antagonists reveal the human-like pharmacology of gerbil NK1 receptors
S Engberg, I Ahlstedt, A Leffler, E Lindström, E Kristensson, A Svensson, ...
Biochemical pharmacology 73 (2), 259-269, 2007
232007
Senktide-induced gerbil foot tapping behaviour is blocked by selective tachykinin NK1 and NK3 receptor antagonists
M Sundqvist, E Kristensson, R Adolfsson, A Leffler, I Ahlstedt, S Engberg, ...
European journal of pharmacology 577 (1-3), 78-86, 2007
132007
Characterization of selective and potent JAK1 inhibitors intended for the inhaled treatment of asthma
M Nilsson, M Rhedin, R Hendrickx, S Berglund, A Piras, P Blomgran, ...
Drug design, development and therapy, 2901-2917, 2023
112023
AZD0284, a potent, selective, and orally bioavailable inverse agonist of retinoic acid receptor-related orphan receptor C2
F Narjes, A Llinas, S von Berg, J Jirholt, S Lever, R Pehrson, M Collins, ...
Journal of Medicinal Chemistry 64 (18), 13807-13829, 2021
102021
Back Cover: Benzoxazepines Achieve Potent Suppression of IL‐17 Release in Human T‐Helper 17 (TH17) Cells through an Induced‐Fit Binding Mode to the …
RI Olsson, Y Xue, S von Berg, A Aagaard, J McPheat, EL Hansson, ...
ChemMedChem 11 (2), 245-245, 2016
2016
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