| Increased spatiotemporal resolution reveals highly dynamic dense tubular matrices in the peripheral ER J Nixon-Abell, CJ Obara, AV Weigel, D Li, WR Legant, CS Xu, HA Pasolli, ... Science 354 (6311), aaf3928, 2016 | 422 | 2016 |
| RNA granules hitchhike on lysosomes for long-distance transport, using annexin A11 as a molecular tether YC Liao, MS Fernandopulle, G Wang, H Choi, L Hao, CM Drerup, R Patel, ... Cell 179 (1), 147-164. e20, 2019 | 394 | 2019 |
| ER proteins decipher the tubulin code to regulate organelle distribution P Zheng, CJ Obara, E Szczesna, J Nixon-Abell, KK Mahalingan, ... Nature 601 (7891), 132-138, 2022 | 76 | 2022 |
| Protective LRRK2 R1398H variant enhances GTPase and Wnt signaling activity J Nixon-Abell, DC Berwick, S Grannó, VA Spain, C Blackstone, K Harvey Frontiers in molecular neuroscience 9, 18, 2016 | 75 | 2016 |
| Pathogenic LRRK2 variants are gain-of-function mutations that enhance LRRK2-mediated repression of β-catenin signaling DC Berwick, B Javaheri, A Wetzel, M Hopkinson, J Nixon-Abell, S Grannò, ... Molecular neurodegeneration 12, 1-17, 2017 | 67 | 2017 |
| Proteomic analysis reveals co-ordinated alterations in protein synthesis and degradation pathways in LRRK2 knockout mice L Pellegrini, DN Hauser, Y Li, A Mamais, A Beilina, R Kumaran, A Wetzel, ... Human molecular genetics 27 (18), 3257-3271, 2018 | 60 | 2018 |
| The importance of naturally attenuated SARS‐CoV‐2 in the fight against COVID‐19 J Armengaud, A Delaunay‐Moisan, JY Thuret, E Van Anken, ... Environmental microbiology 22 (6), 1997-2000, 2020 | 50 | 2020 |
| Tie-line analysis reveals interactions driving heteromolecular condensate formation D Qian, TJ Welsh, NA Erkamp, S Qamar, J Nixon-Abell, G Krainer, ... Physical Review X 12 (4), 041038, 2022 | 33 | 2022 |
| Sequential screening nominates the Parkinson's disease associated kinase LRRK2 as a regulator of Clathrin-mediated endocytosis GR Heaton, N Landeck, A Mamais, MA Nalls, J Nixon-Abell, R Kumaran, ... Neurobiology of disease 141, 104948, 2020 | 29 | 2020 |
| Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampus S Granno, J Nixon-Abell, DC Berwick, J Tosh, G Heaton, S Almudimeegh, ... Scientific reports 9 (1), 7322, 2019 | 29 | 2019 |
| Biomolecular condensate phase diagrams with a combinatorial microdroplet platform WE Arter, R Qi, NA Erkamp, G Krainer, K Didi, TJ Welsh, J Acker, ... Nature Communications 13 (1), 7845, 2022 | 25 | 2022 |
| High-fidelity 3D live-cell nanoscopy through data-driven enhanced super-resolution radial fluctuation RF Laine, HS Heil, S Coelho, J Nixon-Abell, A Jimenez, T Wiesner, ... Nature Methods 20 (12), 1949-1956, 2023 | 20 | 2023 |
| L'RRK de Triomphe: a solution for LRRK2 GTPase activity? J Nixon-Abell, DC Berwick, K Harvey Biochemical Society Transactions 44 (6), 1625-1634, 2016 | 20 | 2016 |
| Spatially non-uniform condensates emerge from dynamically arrested phase separation NA Erkamp, T Sneideris, H Ausserwöger, D Qian, S Qamar, J Nixon-Abell, ... Nature Communications 14 (1), 684, 2023 | 19 | 2023 |
| Transverse endoplasmic reticulum expansion in hereditary spastic paraplegia corticospinal axons PP Zhu, HF Hung, N Batchenkova, J Nixon-Abell, J Henderson, P Zheng, ... Human Molecular Genetics 31 (16), 2779-2795, 2022 | 16 | 2022 |
| Z-α1-antitrypsin polymers impose molecular filtration in the endoplasmic reticulum after undergoing phase transition to a solid state JE Chambers, N Zubkov, M Kubánková, J Nixon-Abell, I Mela, S Abreu, ... Science Advances 8 (14), eabm2094, 2022 | 14 | 2022 |
| Multiplex gene tagging with CRISPR-Cas9 for live-cell microscopy and application to study the role of SARS-CoV-2 proteins in autophagy, mitochondrial dynamics, and cell growth O Perez-Leal, J Nixon-Abell, CA Barrero, JC Gordon, J Oesterling, ... The CRISPR Journal 4 (6), 854-871, 2021 | 14 | 2021 |
| Increased spatiotemporal resolution reveals highly dynamic dense tubular matrices in the peripheral ER. Science. 354: aaf3928 J Nixon-Abell, CJ Obara, AV Weigel, D Li, WR Legant, CS Xu, HA Pasolli, ... | 13 | 2016 |
| Regulation of membrane fluidity by RNF145‐triggered degradation of the lipid hydrolase ADIPOR2 N Volkmar, CM Gawden‐Bone, JC Williamson, J Nixon‐Abell, JA West, ... The EMBO Journal 41 (19), e110777, 2022 | 12 | 2022 |
| Inherited and sporadic amyotrophic lateral sclerosis and fronto-temporal lobar degenerations arising from pathological condensates of phase separating proteins M Fernandopulle, GZ Wang, J Nixon-Abell, S Qamar, V Balaji, R Morihara, ... Human Molecular Genetics 28 (R2), R187-R196, 2019 | 12 | 2019 |
Craig BlackstoneVice Chair, Dept of Neurology, Mass General Hospital & Professor, Harvard Medical SchoolVerified email at mgh.harvard.edu
