The lutropin/choriogonadotropin receptor, a 2002 perspective M Ascoli, F Fanelli, DL Segaloff Endocrine reviews 23 (2), 141-174, 2002 | 950 | 2002 |
Adenosine A2A-dopamine D2 receptor-receptor heteromerization: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer M Canals, D Marcellino, F Fanelli, F Ciruela, P De Benedetti, ... Journal of Biological Chemistry 278 (47), 46741-46749, 2003 | 567 | 2003 |
Constitutively active mutants of the alpha 1B‐adrenergic receptor: role of highly conserved polar amino acids in receptor activation. A Scheer, F Fanelli, T Costa, PG De Benedetti, S Cotecchia The EMBO Journal 15 (14), 3566-3578, 1996 | 480 | 1996 |
Target flexibility: an emerging consideration in drug discovery and design P Cozzini, GE Kellogg, F Spyrakis, DJ Abraham, G Costantino, A Emerson, ... Journal of medicinal chemistry 51 (20), 6237-6255, 2008 | 370 | 2008 |
The activation process of the α1B-adrenergic receptor: Potential role of protonation and hydrophobicity of a highly conserved aspartate A Scheer, F Fanelli, T Costa, PG De Benedetti, S Cotecchia Proceedings of the National Academy of Sciences 94 (3), 808-813, 1997 | 270 | 1997 |
Wordom: a user‐friendly program for the analysis of molecular structures, trajectories, and free energy surfaces M Seeber, A Felline, F Raimondi, S Muff, R Friedman, F Rao, A Caflisch, ... Journal of computational chemistry 32 (6), 1183-1194, 2011 | 268 | 2011 |
Adenosine A2A-dopamine D2 receptor–receptor heteromers. Targets for neuro-psychiatric disorders S Ferré, F Ciruela, M Canals, D Marcellino, J Burgueno, V Casadó, ... Parkinsonism & related disorders 10 (5), 265-271, 2004 | 190 | 2004 |
Computational Modeling Approaches to Structure−Function Analysis of G Protein-Coupled Receptors F Fanelli, PG De Benedetti Chemical Reviews 105 (9), 3297–3351, 2005 | 182 | 2005 |
Adenosine A2A Receptor-Antagonist/Dopamine D2 Receptor-Agonist Bivalent Ligands as Pharmacological Tools to Detect A2A-D2 Receptor Heteromers A Soriano, R Ventura, A Molero, R Hoen, V Casadó, A Cortés, F Fanelli, ... Journal of medicinal chemistry 52 (18), 5590-5602, 2009 | 180 | 2009 |
Mutational analysis of the highly conserved arginine within the Glu/Asp-Arg-Tyr motif of the α1b-adrenergic receptor: effects on receptor isomerization and activation A Scheer, T Costa, F Fanelli, PG De Benedetti, S Mhaouty-Kodja, L Abuin, ... Molecular pharmacology 57 (2), 219-231, 2000 | 149 | 2000 |
Mutagenesis and modelling of the α1b-adrenergic receptor highlight the role of the helix 3/helix 6 interface in receptor activation PJ Greasley, F Fanelli, O Rossier, L Abuin, S Cotecchia Molecular pharmacology 61 (5), 1025-1032, 2002 | 140 | 2002 |
Activation mechanism of human oxytocin receptor: a combined study of experimental and computer-simulated mutagenesis F Fanelli, P Barbier, D Zanchetta, PG de Benedetti, B Chini Molecular Pharmacology 56 (1), 214-225, 1999 | 126 | 1999 |
Single Molecule Analysis of Functionally Asymmetric G Protein-coupled Receptor (GPCR) Oligomers Reveals Diverse Spatial and Structural Assemblies*♦ KC Jonas, F Fanelli, IT Huhtaniemi, AC Hanyaloglu Journal of Biological Chemistry 290 (7), 3875-3892, 2015 | 124 | 2015 |
The KDEL receptor couples to Gαq/11 to activate Src kinases and regulate transport through the Golgi M Giannotta, C Ruggiero, M Grossi, J Cancino, M Capitani, T Pulvirenti, ... The EMBO journal 31 (13), 2869-2881, 2012 | 120 | 2012 |
A functional transmembrane complex: the luteinizing hormone receptor with bound ligand and G protein D Puett, Y Li, G DeMars, K Angelova, F Fanelli Molecular and Cellular Endocrinology 260, 126-136, 2007 | 111 | 2007 |
Hydrophobicity of Residue351 of the G Protein Gi1α Determines the Extent of Activation by the α2A-Adrenoceptor DS Bahia, A Wise, F Fanelli, M Lee, S Rees, G Milligan Biochemistry 37 (33), 11555-11562, 1998 | 110 | 1998 |
Theoretical investigation of substrate specificity for cytochromes P450 IA2, P450 IID6 and P450 IIIA4 F De Rienzo, F Fanelli, MC Menziani, PG De Benedetti Journal of computer-aided molecular design 14, 93-116, 2000 | 105 | 2000 |
Mutational and Computational Analysis of the α1b-Adrenergic Receptor: INVOLVEMENT OF BASIC AND HYDROPHOBIC RESIDUES IN RECEPTOR ACTIVATION AND G PROTEIN COUPLING* 210 PJ Greasley, F Fanelli, A Scheer, L Abuin, M Nenniger-Tosato, ... Journal of Biological Chemistry 276 (49), 46485-46494, 2001 | 104 | 2001 |
The intellectual disability protein RAB39B selectively regulates GluA2 trafficking to determine synaptic AMPAR composition ML Mignogna, M Giannandrea, A Gurgone, F Fanelli, F Raimondi, ... Nature communications 6 (1), 6504, 2015 | 101 | 2015 |
Inverse agonism and neutral antagonism at α1a-and α1b-adrenergic receptor subtypes O Rossier, L Abuin, F Fanelli, A Leonardi, S Cotecchia Molecular pharmacology 56 (5), 858-866, 1999 | 101 | 1999 |