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Michael Ehrenstein
Michael Ehrenstein
Verified email at ucl.ac.uk
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Year
CD19+ CD24hiCD38hi B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic lupus erythematosus patients
PA Blair, LY Noreņa, F Flores-Borja, DJ Rawlings, DA Isenberg, ...
immunity 32 (1), 129-140, 2010
17322010
Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFα therapy
MR Ehrenstein, JG Evans, A Singh, S Moore, G Warnes, DA Isenberg, ...
The Journal of experimental medicine 200 (3), 277-285, 2004
16692004
An open study of B lymphocyte depletion in systemic lupus erythematosus
MJ Leandro, JC Edwards, G Cambridge, MR Ehrenstein, DA Isenberg
Arthritis & Rheumatism 46 (10), 2673-2677, 2002
7652002
CD19+ CD24hiCD38hi B cells maintain regulatory T cells while limiting TH1 and TH17 differentiation
F Flores-Borja, A Bosma, D Ng, V Reddy, MR Ehrenstein, DA Isenberg, ...
Science translational medicine 5 (173), 173ra23-173ra23, 2013
7462013
The importance of natural IgM: scavenger, protector and regulator
MR Ehrenstein, CA Notley
Nature Reviews Immunology 10 (11), 778-786, 2010
7172010
Novel suppressive function of transitional 2 B cells in experimental arthritis
JG Evans, KA Chavez-Rueda, A Eddaoudi, A Meyer-Bahlburg, ...
The Journal of Immunology 178 (12), 7868-7878, 2007
6832007
Reconstitution of peripheral blood B cells after depletion with rituximab in patients with rheumatoid arthritis
MJ Leandro, G Cambridge, MR Ehrenstein, JCW Edwards
Arthritis & Rheumatism: Official Journal of the American College of …, 2006
6262006
Serologic changes following B lymphocyte depletion therapy for rheumatoid arthritis
G Cambridge, MJ Leandro, JCW Edwards, MR Ehrenstein, M Salden, ...
Arthritis & Rheumatism: Official Journal of the American College of …, 2003
5982003
Anti–TNF-α therapy induces a distinct regulatory T cell population in patients with rheumatoid arthritis via TGF-β
S Nadkarni, C Mauri, MR Ehrenstein
The Journal of experimental medicine 204 (1), 33-39, 2007
5962007
Mice lacking endogenous IL-10–producing regulatory B cells develop exacerbated disease and present with an increased frequency of Th1/Th17 but a decrease in regulatory T cells
NA Carter, R Vasconcellos, EC Rosser, C Tulone, A Muņoz-Suano, ...
The Journal of Immunology 186 (10), 5569-5579, 2011
5382011
The classical pathway is the dominant complement pathway required for innate immunity to Streptococcus pneumoniae infection in mice
JS Brown, T Hussell, SM Gilliland, DW Holden, JC Paton, MR Ehrenstein, ...
Proceedings of the National Academy of Sciences 99 (26), 16969-16974, 2002
4902002
B-cell depletion in the treatment of patients with systemic lupus erythematosus: a longitudinal analysis of 24 patients
MJ Leandro, G Cambridge, JC Edwards, MR Ehrenstein, DA Isenberg
Rheumatology 44 (12), 1542-1545, 2005
4622005
Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting
C Rada, MR Ehrenstein, MS Neuberger, C Milstein
Immunity 9 (1), 135-141, 1998
4131998
Human FoxP3+ regulatory T cells in systemic autoimmune diseases
M Miyara, G Gorochov, M Ehrenstein, L Musset, S Sakaguchi, Z Amoura
Autoimmunity reviews 10 (12), 744-755, 2011
4062011
The ‘short’history of regulatory B cells
C Mauri, MR Ehrenstein
Trends in immunology 29 (1), 34-40, 2008
3992008
Selective targeting of B cells with agonistic anti-CD40 is an efficacious strategy for the generation of induced regulatory T2-like B cells and for the suppression of lupus in …
PA Blair, KA Chavez-Rueda, JG Evans, MJ Shlomchik, A Eddaoudi, ...
The Journal of Immunology 182 (6), 3492-3502, 2009
3652009
Fifty years of anti-ds DNA antibodies: are we approaching journey's end?
DA Isenberg, JJ Manson, MR Ehrenstein, A Rahman
Oxford University Press 46 (7), 1052-1056, 2007
3572007
Defects in CTLA-4 are associated with abnormal regulatory T cell function in rheumatoid arthritis
F Flores-Borja, EC Jury, C Mauri, MR Ehrenstein
Proceedings of the National Academy of Sciences 105 (49), 19396-19401, 2008
3532008
International consensus outcome measures for patients with idiopathic inflammatory myopathies. Development and initial validation of myositis activity and damage indices in …
DA Isenberg, E Allen, V Farewell, MR Ehrenstein, MG Hanna, ...
Rheumatology 43 (1), 49-54, 2004
3532004
A retrospective seven‐year analysis of the use of B cell depletion therapy in systemic lupus erythematosus at university college london hospital: the first fifty patients
TYT Lu, KP Ng, G Cambridge, MJ Leandro, JCW Edwards, M Ehrenstein, ...
Arthritis Care & Research: Official Journal of the American College of …, 2009
3232009
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