Follow
Daniel Leonard
Daniel Leonard
MD/PhD student, Cleveleand Clinic Lerner College of Medicine at Case Western Reserve University
Verified email at case.edu
Title
Cited by
Cited by
Year
M2-like macrophages are responsible for collagen degradation through a mannose receptor–mediated pathway
DH Madsen, D Leonard, A Masedunskas, A Moyer, HJ Jürgensen, ...
Journal of Cell Biology 202 (6), 951-966, 2013
3342013
Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth
J Sangodkar, A Perl, R Tohme, J Kiselar, DB Kastrinsky, N Zaware, ...
The Journal of clinical investigation 127 (6), 2081-2090, 2017
1802017
Therapeutic targeting of PP2A
CM O’Connor, A Perl, D Leonard, J Sangodkar, G Narla
The international journal of biochemistry & cell biology 96, 182-193, 2018
1792018
Selective PP2A enhancement through biased heterotrimer stabilization
D Leonard, W Huang, S Izadmehr, CM O’Connor, DD Wiredja, Z Wang, ...
Cell 181 (3), 688-701. e16, 2020
1262020
The highly recurrent PP2A Aα-subunit mutation P179R alters protein structure and impairs PP2A enzyme function to promote endometrial tumorigenesis
SE Taylor, CM O'Connor, Z Wang, G Shen, H Song, D Leonard, ...
Cancer research 79 (16), 4242-4257, 2019
452019
Inactivation of PP2A by a recurrent mutation drives resistance to MEK inhibitors
CM O’Connor, D Leonard, D Wiredja, RA Avelar, Z Wang, D Schlatzer, ...
Oncogene 39 (3), 703-717, 2020
342020
Par-1b is required for morphogenesis and differentiation of myoepithelial cells during salivary gland development
EM Gervais, SJ Sequeira, W Wang, S Abraham, JH Kim, D Leonard, ...
Organogenesis 12 (4), 194-216, 2016
232016
Challenges and reinterpretation of antibody-based research on phosphorylation of Tyr307 on PP2Ac
S Mazhar, D Leonard, A Sosa, D Schlatzer, D Thomas, G Narla
Cell reports 30 (9), 3164-3170. e3, 2020
192020
Active and passive destabilization of G-quadruplex DNA by the telomere POT1-TPP1 complex
M Xu, A Axhemi, M Malgowska, Y Chen, D Leonard, S Srinivasan, ...
Journal of molecular biology 433 (7), 166846, 2021
72021
Pack a STRIPAK with hubs inside a hub
W Huang, D Leonard, DJ Taylor
Nature structural & molecular biology 28 (3), 232-233, 2021
62021
A Reply to'Cellular Toxicity of iHAP1 and DT-061 Does Not Occur Through PP2A-B56 Targeting'
D Leonard, W Huang, DL Brautigan, A DiFeo, C O'Connor, E Ogris, ...
Available at SSRN 3950751, 0
1
Data for EMSL Project 51062 from September 2021
H Scott, D Leonard, D Taylor, W Huang
Pacific Northwest National Lab.(PNNL), Richland, WA (United States …, 2021
2021
Orchestrating PP2A Holoenzyme Assembly: From Normal to Abnormal and the Therapeutic Opportunity in Between
DJ Leonard
Case Western Reserve University, 2021
2021
Data for EMSL Project 51062 from December 2020
H Scott, D Leonard, D Taylor, W Huang
Pacific Northwest National Lab.(PNNL), Richland, WA (United States …, 2020
2020
Biased activation of PP2A through selective heterotrimer binding and stabilization
D Leonard, W Huang, S Izadmehr, CM O'Connor, DD Wiredja, Z Wang, ...
Cancer Research 80 (16_Supplement), 2981-2981, 2020
2020
Data for EMSL Project 51062 from March 2020
H Scott, D Leonard, D Taylor, W Huang
Pacific Northwest National Lab.(PNNL), Richland, WA (United States …, 2020
2020
Drug target mutations as a mechanism of acquired resistance to small molecules activators of protein phosphatase 2a
R Tohme, J Sangodkar, J Kiselar, D Leonard, C O'Connor, S Gandhe, ...
Cancer Research 77 (13_Supplement), 4173-4173, 2017
2017
A novel M2-like macrophage mediated intracellular collagen degradation pathway identified by intravital imaging
DH Madsen, D Leonard, A Masedunskas, A Moyer, HJ Jurgensen, ...
MOLECULAR BIOLOGY OF THE CELL 24, 2013
2013
The system can't perform the operation now. Try again later.
Articles 1–18