Antimicrobial resistance to ceftazidime involving loss of penicillin-binding protein 3 in Burkholderia pseudomallei N Chantratita, DA Rholl, B Sim, V Wuthiekanun, D Limmathurotsakul, ... Proceedings of the National Academy of Sciences 108 (41), 17165-17170, 2011 | 172 | 2011 |
Mutation hotspots at CTCF binding sites coupled to chromosomal instability in gastrointestinal cancers YA Guo, MM Chang, W Huang, WF Ooi, M Xing, P Tan, AJ Skanderup Nature communications 9 (1), 1520, 2018 | 148 | 2018 |
VHL Deficiency Drives Enhancer Activation of Oncogenes in Clear Cell Renal Cell Carcinoma X Yao, J Tan, KJ Lim, J Koh, WF Ooi, Z Li, D Huang, M Xing, YS Chan, ... Cancer discovery 7 (11), 1284-1305, 2017 | 131 | 2017 |
Epigenomic profiling of primary gastric adenocarcinoma reveals super-enhancer heterogeneity WF Ooi, M Xing, C Xu, X Yao, MK Ramlee, MC Lim, F Cao, K Lim, D Babu, ... Nature communications 7 (1), 12983, 2016 | 130 | 2016 |
A Burkholderia pseudomallei toxin inhibits helicase activity of translation factor eIF4A A Cruz-Migoni, GM Hautbergue, PJ Artymiuk, PJ Baker, M Bokori-Brown, ... Science 334 (6057), 821-824, 2011 | 128 | 2011 |
The Condition-Dependent Transcriptional Landscape of Burkholderia pseudomallei WF Ooi, C Ong, T Nandi, JF Kreisberg, HH Chua, G Sun, Y Chen, ... PLoS genetics 9 (9), e1003795, 2013 | 91 | 2013 |
Genomic acquisition of a capsular polysaccharide virulence cluster by non-pathogenic Burkholderia isolates BMQ Sim, N Chantratita, WF Ooi, T Nandi, R Tewhey, V Wuthiekanun, ... Genome biology 11, 1-17, 2010 | 90 | 2010 |
Nanoscale chromatin profiling of gastric adenocarcinoma reveals cancer-associated cryptic promoters and somatically acquired regulatory elements M Muratani, N Deng, WF Ooi, SJ Lin, M Xing, C Xu, A Qamra, ST Tay, ... Nature communications 5 (1), 4361, 2014 | 83 | 2014 |
Epigenomic promoter alterations amplify gene isoform and immunogenic diversity in gastric adenocarcinoma A Qamra, M Xing, N Padmanabhan, JJT Kwok, S Zhang, C Xu, YS Leong, ... Cancer discovery 7 (6), 630-651, 2017 | 50 | 2017 |
HoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesis TD Yan, WF Ooi, A Qamra, A Cheung, DL Ma, GM Sundaram, C Xu, ... Nature communications 9 (1), 100, 2018 | 48 | 2018 |
Integrated paired-end enhancer profiling and whole-genome sequencing reveals recurrent CCNE1 and IGF2 enhancer hijacking in primary gastric adenocarcinoma WF Ooi, AM Nargund, KJ Lim, S Zhang, M Xing, A Mandoli, JQ Lim, ... Gut 69 (6), 1039-1052, 2020 | 46 | 2020 |
HNF4α pathway mapping identifies wild-type IDH1 as a targetable metabolic node in gastric cancer C Xu, WF Ooi, A Qamra, J Tan, BYJ Chua, SWT Ho, K Das, ZFA Isa, Z Li, ... Gut 69 (2), 231-242, 2020 | 33 | 2020 |
Segmental chromosome aberrations converge on overexpression of mitotic spindle regulatory genes in high‐risk neuroblastoma WF Ooi, A Re, V Sidarovich, V Canella, N Arseni, V Adami, ... Genes, Chromosomes and Cancer 51 (6), 545-556, 2012 | 20 | 2012 |
Evolutionary analysis of Burkholderia pseudomallei identifies putative novel virulence genes, including a microbial regulator of host cell autophagy AP Singh, S Lai, T Nandi, HH Chua, WF Ooi, C Ong, JD Boyce, B Adler, ... Journal of bacteriology 195 (24), 5487-5498, 2013 | 19 | 2013 |
Transcriptional profiles of Burkholderia pseudomallei reveal the direct and indirect roles of Sigma E under oxidative stress conditions S Jitprasutwit, C Ong, N Juntawieng, WF Ooi, CM Hemsley, ... BMC genomics 15, 1-11, 2014 | 17 | 2014 |
Regulatory enhancer profiling of mesenchymal-type gastric cancer reveals subtype-specific epigenomic landscapes and targetable vulnerabilities SWT Ho, T Sheng, M Xing, WF Ooi, C Xu, R Sundar, KK Huang, Z Li, ... Gut 72 (2), 226-241, 2023 | 15 | 2023 |
Genomic and epigenomic EBF1 alterations modulate TERT expression in gastric cancer M Xing, WF Ooi, J Tan, A Qamra, PH Lee, Z Li, C Xu, N Padmanabhan, ... The Journal of clinical investigation 130 (6), 3005-3020, 2020 | 15 | 2020 |
Epigenomic promoter alterations amplify gene isoform and immunogenic diversity in gastric adenocarcinoma. Cancer Discov. 2017; 7: 630–651. doi: 10.1158/2159-8290 A Qamra, M Xing, N Padmanabhan, JJT Kwok, S Zhang, C Xu, YS Leong, ... CD-16-1022.[Abstract][CrossRef][Google Scholar], 0 | 15 | |
VHL deficiency drives enhancer activation of oncogenes in clear cell renal cell carcinoma. Cancer Discov. 2017; 7: 1284–1305. doi: 10.1158/2159-8290 X Yao, J Tan, KJ Lim, J Koh, WF Ooi, Z Li, D Huang, M Xing, YS Chan, ... CD-17-0375.[Abstract][CrossRef][Google Scholar], 0 | 14 | |
Chromatin rewiring by mismatch repair protein MSH2 alters cell adhesion pathways and sensitivity to BET inhibition in gastric cancer AM Nargund, C Xu, A Mandoli, A Okabe, GB Chen, KK Huang, T Sheng, ... Cancer Research 82 (14), 2538-2551, 2022 | 8 | 2022 |