| Essential regulation of cell bioenergetics by constitutive InsP 3 receptor Ca 2+ transfer to mitochondria C Cárdenas, RA Miller, I Smith, T Bui, J Molgó, M Müller, H Vais, ... Cell 142 (2), 270-283, 2010 | 1094 | 2010 |
| Fluorescence Microscopy MJ Sanderson, I Smith, I Parker, MD Bootman Cold Spring Harbor Protocols 2014 (10), pdb. top071795, 2014 | 499 | 2014 |
| The production of amyloid β peptide is a critical requirement for the viability of central neurons LD Plant, JP Boyle, IF Smith, C Peers, HA Pearson The Journal of neuroscience 23 (13), 5531-5535, 2003 | 436 | 2003 |
| Enhanced ryanodine receptor recruitment contributes to Ca2+ disruptions in young, adult, and aged Alzheimer's disease mice GE Stutzmann, I Smith, A Caccamo, S Oddo, FM LaFerla, I Parker The Journal of neuroscience 26 (19), 5180-5189, 2006 | 384 | 2006 |
| SERCA pump activity is physiologically regulated by presenilin and regulates amyloid β production KN Green, A Demuro, Y Akbari, BD Hitt, IF Smith, I Parker, FM LaFerla The Journal of cell biology 181 (7), 1107-1116, 2008 | 349 | 2008 |
| A dynamic relationship between intracellular and extracellular pools of Aβ S Oddo, A Caccamo, IF Smith, KN Green, FM LaFerla The American journal of pathology 168 (1), 184-194, 2006 | 307 | 2006 |
| Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer’s disease A McQuade, YJ Kang, J Hasselmann, A Jairaman, A Sotelo, M Coburn, ... Nature communications 11 (1), 1-17, 2020 | 204 | 2020 |
| Imaging the quantal substructure of single IP3R channel activity during Ca2+ puffs in intact mammalian cells IF Smith, I Parker Proceedings of the National Academy of Sciences 106 (15), 6404-6409, 2009 | 204 | 2009 |
| Tunneling nanotubes and gap junctions–their role in long-range intercellular communication during development, health, and disease conditions J Ariazi, A Benowitz, V De Biasi, ML Den Boer, S Cherqui, H Cui, ... Frontiers in molecular neuroscience 10, 333, 2017 | 200 | 2017 |
| Enhanced caffeine‐induced Ca2+ release in the 3xTg‐AD mouse model of Alzheimer's disease IF Smith, B Hitt, KN Green, S Oddo, FM LaFerla Journal of neurochemistry 94 (6), 1711-1718, 2005 | 196 | 2005 |
| A comparison of fluorescent Ca 2+ indicators for imaging local Ca 2+ signals in cultured cells JT Lock, I Parker, IF Smith Cell calcium 58 (6), 638-648, 2015 | 192 | 2015 |
| Calcium dysregulation in Alzheimer's disease: recent advances gained from genetically modified animals IF Smith, KN Green, FM LaFerla Cell calcium 38 (3), 427-437, 2005 | 164 | 2005 |
| Enhanced Ryanodine‐Mediated Calcium Release in Mutant PS1‐Expressing Alzheimer's Mouse Models GE Stutzmann, I Smith, A Caccamo, S Oddo, I Parker, F Laferla Annals of the New York Academy of Sciences 1097 (1), 265-277, 2007 | 134 | 2007 |
| Localization of puff sites adjacent to the plasma membrane: functional and spatial characterization of Ca 2+ signaling in SH-SY5Y cells utilizing membrane-permeant caged IP 3 IF Smith, SM Wiltgen, I Parker Cell calcium 45 (1), 65-76, 2009 | 117 | 2009 |
| Active generation and propagation of Ca 2+ signals within tunneling membrane nanotubes IF Smith, J Shuai, I Parker Biophysical journal 100 (8), L37-L39, 2011 | 98 | 2011 |
| Ca2+ puffs originate from pre-established stable clusters of inositol trisphosphate receptors IF Smith, SM Wiltgen, J Shuai, I Parker Science signaling 2 (98), ra77, 2009 | 84 | 2009 |
| An algorithm for automated detection, localization and measurement of local calcium signals from camera-based imaging KL Ellefsen, B Settle, I Parker, IF Smith Cell calcium 56 (3), 147-156, 2014 | 83 | 2014 |
| Role of calcium in the pathogenesis of Alzheimer’s disease and transgenic models KN Green, IF Smith, FM Laferla Calcium Signalling and Disease, 507-521, 2007 | 82 | 2007 |
| Ca 2+ stores and capacitative Ca 2+ entry in human neuroblastoma (SH-SY5Y) cells expressing a familial Alzheimer’s disease presenilin-1 mutation IF Smith, JP Boyle, PFT Vaughan, HA Pearson, RF Cowburn, CS Peers Brain research 949 (1), 105-111, 2002 | 67 | 2002 |
| Timescales of IP 3-evoked Ca 2+ spikes emerge from Ca 2+ puffs only at the cellular level K Thurley, IF Smith, SC Tovey, CW Taylor, I Parker, M Falcke Biophysical journal 101 (11), 2638-2644, 2011 | 64 | 2011 |
