| Influence of affinity and antigen internalization on the uptake and penetration of Anti-HER2 antibodies in solid tumors SI Rudnick, J Lou, CC Shaller, Y Tang, AJP Klein-Szanto, LM Weiner, ... Cancer research 71 (6), 2250-2259, 2011 | 376 | 2011 |
| Sequence variation within botulinum neurotoxin serotypes impacts antibody binding and neutralization TJ Smith, J Lou, IN Geren, CM Forsyth, R Tsai, SL Laporte, WH Tepp, ... Infection and immunity 73 (9), 5450-5457, 2005 | 329 | 2005 |
| Molecular evolution of antibody cross-reactivity for two subtypes of type A botulinum neurotoxin C Garcia-Rodriguez, R Levy, JW Arndt, CM Forsyth, A Razai, J Lou, ... Nature biotechnology 25 (1), 107-116, 2007 | 229 | 2007 |
| Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin αvβ8–mediated activation of TGF-β H Kitamura, S Cambier, S Somanath, T Barker, S Minagawa, J Markovics, ... The Journal of clinical investigation 121 (7), 2863-2875, 2011 | 212 | 2011 |
| Molecular evolution of antibody affinity for sensitive detection of botulinum neurotoxin type A A Razai, C Garcia-Rodriguez, J Lou, IN Geren, CM Forsyth, Y Robles, ... Journal of molecular biology 351 (1), 158-169, 2005 | 178 | 2005 |
| Yeast mating for combinatorial Fab library generation and surface display JM Weaver-Feldhaus, J Lou, JR Coleman, RW Siegel, JD Marks, ... FEBS letters 564 (1-2), 24-34, 2004 | 149 | 2004 |
| Regulation of antibody-dependent cellular cytotoxicity by IgG intrinsic and apparent affinity for target antigen Y Tang, J Lou, RK Alpaugh, MK Robinson, JD Marks, LM Weiner The Journal of Immunology 179 (5), 2815-2823, 2007 | 145 | 2007 |
| Cryo-EM reveals integrin-mediated TGF-β activation without release from latent TGF-β MG Campbell, A Cormier, S Ito, RI Seed, AJ Bondesson, J Lou, JD Marks, ... Cell 180 (3), 490-501. e16, 2020 | 122 | 2020 |
| Using phage display to select antibodies recognizing post-translational modifications independently of sequence context JW Kehoe, N Velappan, M Walbolt, J Rasmussen, D King, J Lou, K Knopp, ... Molecular & Cellular Proteomics 5 (12), 2350-2363, 2006 | 104 | 2006 |
| Antibodies in haystacks: how selection strategy influences the outcome of selection from molecular diversity libraries J Lou, R Marzari, V Verzillo, F Ferrero, D Pak, M Sheng, C Yang, ... Journal of immunological methods 253 (1-2), 233-242, 2001 | 99 | 2001 |
| A single-domain llama antibody potently inhibits the enzymatic activity of botulinum neurotoxin by binding to the non-catalytic α-exosite binding region J Dong, AA Thompson, Y Fan, J Lou, F Conrad, M Ho, M Pires-Alves, ... Journal of molecular biology 397 (4), 1106-1118, 2010 | 98 | 2010 |
| Integrin αvβ8–expressing tumor cells evade host immunity by regulating TGF-β activation in immune cells N Takasaka, RI Seed, A Cormier, AJ Bondesson, J Lou, A Elattma, S Ito, ... JCI insight 3 (20), 2018 | 97 | 2018 |
| Antibody protection against botulinum neurotoxin intoxication in mice LW Cheng, LH Stanker, TD Henderson, J Lou, JD Marks Infection and immunity 77 (10), 4305-4313, 2009 | 94 | 2009 |
| Selective targeting of TGF-β activation to treat fibroinflammatory airway disease S Minagawa, J Lou, RI Seed, A Cormier, S Wu, Y Cheng, L Murray, P Tsui, ... Science translational medicine 6 (241), 241ra79-241ra79, 2014 | 90 | 2014 |
| Neutralizing human monoclonal antibodies binding multiple serotypes of botulinum neurotoxin C Garcia-Rodriguez, IN Geren, J Lou, F Conrad, C Forsyth, W Wen, ... Protein engineering, design & selection 24 (3), 321-331, 2011 | 81 | 2011 |
| Impact of intrinsic affinity on functional binding and biological activity of EGFR antibodies Y Zhou, AL Goenaga, BD Harms, H Zou, J Lou, F Conrad, GP Adams, ... Molecular cancer therapeutics 11 (7), 1467-1476, 2012 | 80 | 2012 |
| Antibodies in proteomics I: generating antibodies A Bradbury, N Velappan, V Verzillo, M Ovecka, L Chasteen, D Sblattero, ... TRENDS in Biotechnology 21 (6), 275-281, 2003 | 78 | 2003 |
| Antibodies in proteomics II: screening, high-throughput characterization and downstream applications A Bradbury, N Velappan, V Verzillo, M Ovecka, L Chasteen, D Sblattero, ... Trends in biotechnology 21 (7), 312-317, 2003 | 74 | 2003 |
| Extraction and inhibition of enzymatic activity of botulinum neurotoxins/A1,/A2, and/A3 by a panel of monoclonal anti-BoNT/A antibodies SR Kalb, J Lou, C Garcia-Rodriguez, IN Geren, TJ Smith, H Moura, ... Plos one 4 (4), e5355, 2009 | 73 | 2009 |
| Quantum dot immunoassays in renewable surface column and 96-well plate formats for the fluorescence detection of botulinum neurotoxin using high-affinity antibodies MG Warner, JW Grate, A Tyler, RM Ozanich, KD Miller, J Lou, JD Marks, ... Biosensors and Bioelectronics 25 (1), 179-184, 2009 | 71 | 2009 |
