POT1 loss-of-function variants predispose to familial melanoma CD Robles-Espinoza, M Harland, AJ Ramsay, LG Aoude, V Quesada, ... Nature genetics 46 (5), 478-481, 2014 | 286 | 2014 |
Genome sequencing of normal cells reveals developmental lineages and mutational processes S Behjati, M Huch, R van Boxtel, W Karthaus, DC Wedge, AU Tamuri, ... Nature 513 (7518), 422-425, 2014 | 259 | 2014 |
Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBEC-dependent mutations in breast cancer S Nik-Zainal, DC Wedge, LB Alexandrov, M Petljak, AP Butler, N Bolli, ... Nature genetics 46 (5), 487, 2014 | 234 | 2014 |
Somatic mutations reveal asymmetric cellular dynamics in the early human embryo YS Ju, I Martincorena, M Gerstung, M Petljak, LB Alexandrov, R Rahbari, ... Nature 543 (7647), 714-718, 2017 | 162 | 2017 |
Characterizing Mutational Signatures in Human Cancer Cell Lines Reveals Episodic APOBEC Mutagenesis M Petljak, LB Alexandrov, JS Brammeld, S Price, DC Wedge, ... Cell 176 (6), 1282-1294. e20, 2019 | 120 | 2019 |
Understanding mutagenesis through delineation of mutational signatures in human cancer M Petljak, LB Alexandrov Carcinogenesis 37 (6), 531-540, 2016 | 78 | 2016 |
Biological and prognostic impact of APOBEC-induced mutations in the spectrum of plasma cell dyscrasias and multiple myeloma cell lines F Maura, M Petljak, M Lionetti, I Cifola, W Liang, E Pinatel, LB Alexandrov, ... Leukemia 32 (4), 1043-1047, 2018 | 45 | 2018 |
Germline TERT promoter mutations are rare in familial melanoma M Harland, M Petljak, CD Robles-Espinoza, Z Ding, NA Gruis, ... Familial cancer 15 (1), 139-144, 2016 | 39 | 2016 |
Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations JS Brammeld, M Petljak, I Martincorena, SP Williams, LG Alonso, ... Genome research 27 (4), 613-625, 2017 | 22 | 2017 |
Tissue-Biased Expansion of DNMT3A-Mutant Clones in a Mosaic Individual Is Associated with Conserved Epigenetic Erosion A Tovy, JM Reyes, MC Gundry, L Brunetti, H Lee-Six, M Petljak, HJ Park, ... Cell Stem Cell, 2020 | 3 | 2020 |
Molecular Origins of APOBEC-Associated Mutations in Cancer M Petljak, J Maciejowski DNA Repair, 102905, 2020 | 3 | 2020 |
Mosaic DNMT3A Germline Mutation As a Model for Mutant DNMT3A Competitive Advantage in the Blood Lineage A Tovy, HJ Park, JM Reyes, A Guzman, RE Rau, A Jeffries, M Jonnathan, ... Blood 132 (Supplement 1), 173-173, 2018 | | 2018 |
Biological and Prognostic Impact of Apobec-Induced Mutations in the Spectrum of Plasma Cell Dyscrasias F Maura, M Petljak, M Lionetti, I Cifola, W Liang, E Pinatel, L Alexadrov, ... Blood 130 (Supplement 1), 1771-1771, 2017 | | 2017 |
The apobec mutational activity in multiple myeloma: from diagnosis to cell lines F Maura, M Petljak, S Minvielle, R Szalat, M Lionetti, I Cifola, W Liang, ... Congress of the Italian-Society-of-Hematology 102 (suppl. 3), 124-124, 2017 | | 2017 |
THE 2016 CARCINOGENESIS AWARD WINNERS M Petljak, LB Alexandrov, M Karin, D Dhar Carcinogenesis 37 (6), 2016 | | 2016 |
POT1 mutations predispose to familial melanoma CD Robles-Espinoza, M Harland, AJ Ramsay, LG Aoude, V Quesada, ... Cancer Research 74 (23 Supplement), 20-20, 2014 | | 2014 |
Newly identified melanoma susceptibility genes in families highlight the importance of the telomere in melanoma carcinogenesis and prognosis J Newton-Bishop, M Harland, CD Robles-Espinoza, M Iles, M Petljak, ... | | |
King’s Research Portal YS Ju, I Martincorena, M Gerstung, M Petljak, LB Alexandrov, R Rahbari, ... | | |