Nicola Manfrini
Nicola Manfrini
UniversitÓ Degli Studi di Milano - INGM
Email verificata su - Home page
Citata da
Citata da
Role of microRNAs in translation regulation and cancer
S Oliveto, M Mancino, N Manfrini, S Biffo
World journal of biological chemistry 8 (1), 45, 2017
Mechanisms and regulation of DNA end resection
MP Longhese, D Bonetti, N Manfrini, M Clerici
The EMBO journal 29 (17), 2864-2874, 2010
The translational machinery of human CD4+ T cells is poised for activation and controls the switch from quiescence to metabolic remodeling
S Ricciardi, N Manfrini, R Alfieri, P Calamita, MC Crosti, S Gallo, R MŘller, ...
Cell metabolism 28 (6), 895-906. e5, 2018
DNA double-strand breaks in meiosis: checking their formation, processing and repair
MP Longhese, D Bonetti, I Guerini, N Manfrini, M Clerici
DNA repair 8 (9), 1127-1138, 2009
Regulation of the DNA damage response by cyclin-dependent kinases
C Trovesi, N Manfrini, M Falcettoni, MP Longhese
Journal of molecular biology 425 (23), 4756-4766, 2013
Processing of meiotic DNA double strand breaks requires cyclin-dependent kinase and multiple nucleases
N Manfrini, I Guerini, A Citterio, G Lucchini, MP Longhese
Journal of biological chemistry 285 (15), 11628-11637, 2010
The MRX complex plays multiple functions in resection of Yku-and Rif2-protected DNA ends
D Bonetti, M Clerici, N Manfrini, G Lucchini, MP Longhese
PloS one 5 (11), e14142, 2010
RACK1 specifically regulates translation through its binding to ribosomes
S Gallo, S Ricciardi, N Manfrini, E Pesce, S Oliveto, P Calamita, ...
Molecular and cellular biology 38 (23), e00230-18, 2018
Role of the Saccharomyces cerevisiae Rad53 Checkpoint Kinase in Signaling Double-Strand Breaks during the Meiotic Cell Cycle
H Cartagena-Lirola, I Guerini, N Manfrini, G Lucchini, MP Longhese
Molecular and cellular biology 28 (14), 4480-4493, 2008
Working hard at the nexus between cell signaling and the ribosomal machinery: an insight into the roles of RACK1 in translational regulation
S Gallo, N Manfrini
Translation 3 (2), e1120382, 2015
Exosomes recovered from the plasma of COVID-19 patients expose SARS-CoV-2 spike-derived fragments and contribute to the adaptive immune response
E Pesce, N Manfrini, C Cordiglieri, S Santi, A Bandera, A Gobbini, ...
Frontiers in Immunology 12, 785941, 2022
RNA‐processing proteins regulate Mec1/ATR activation by promoting generation of RPA‐coated ss DNA
N Manfrini, C Trovesi, M Wery, M Martina, D Cesena, M Descrimes, ...
EMBO reports 16 (2), 221-231, 2015
Crosstalks between translation and metabolism in cancer
S Biffo, N Manfrini, S Ricciardi
Current opinion in genetics & development 48, 75-81, 2018
FAM46C and FNDC3A are multiple myeloma tumor suppressors that act in concert to impair clearing of protein aggregates and autophagy
N Manfrini, M Mancino, A Miluzio, S Oliveto, M Balestra, P Calamita, ...
Cancer Research 80 (21), 4693-4706, 2020
Resection is responsible for loss of transcription around a double-strand break in Saccharomyces cerevisiae
N Manfrini, M Clerici, M Wery, CV Colombo, M Descrimes, A Morillon, ...
Elife 4, e08942, 2015
Translational control by mTOR-independent routes: how eIF6 organizes metabolism
A Miluzio, S Ricciardi, N Manfrini, R Alfieri, S Oliveto, D Brina, S Biffo
Biochemical Society Transactions 44 (6), 1667-1673, 2016
Ribosomal RACK1 promotes proliferation of neuroblastoma cells independently of global translation upregulation
N Romano, M Veronese, N Manfrini, L Zolla, M Ceci
Cellular signalling 53, 102-110, 2019
Targeting of eIF6-driven translation induces a metabolic rewiring that reduces NAFLD and the consequent evolution to hepatocellular carcinoma
A Scagliola, A Miluzio, G Ventura, S Oliveto, C Cordiglieri, N Manfrini, ...
Nature Communications 12 (1), 4878, 2021
High levels of eukaryotic Initiation Factor 6 (eIF6) are required for immune system homeostasis and for steering the glycolytic flux of TCR-stimulated CD4+ T cells in both miceá…
N Manfrini, S Ricciardi, A Miluzio, M Fedeli, A Scagliola, S Gallo, D Brina, ...
Developmental & Comparative Immunology 77, 69-76, 2017
Discovery and preliminary characterization of translational modulators that impair the binding of eIF6 to 60S ribosomal subunits
E Pesce, A Miluzio, L Turcano, C Minici, D Cirino, P Calamita, N Manfrini, ...
Cells 9 (1), 172, 2020
Il sistema al momento non pu˛ eseguire l'operazione. Riprova pi¨ tardi.
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