Bruno Gran
Bruno Gran
Consultant Neurologist and Honorary Professor of Neurology - NUH NHS Trust
Email verificata su - Home page
Citata da
Citata da
Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS)
CS Constantinescu, N Farooqi, K O'Brien, B Gran
British journal of pharmacology 164 (4), 1079-1106, 2011
Encephalitogenic potential of the myelin basic protein peptide (amino acids 83–99) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligand
B Bielekova, B Goodwin, N Richert, I Cortese, T Kondo, G Afshar, B Gran, ...
Nature medicine 6 (10), 1167-1175, 2000
Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27–stimulated T cells
DC Fitzgerald, GX Zhang, M El-Behi, Z Fonseca-Kelly, H Li, S Yu, ...
Nature immunology 8 (12), 1372-1379, 2007
IL-12p35-deficient mice are susceptible to experimental autoimmune encephalomyelitis: evidence for redundancy in the IL-12 system in the induction of central nervous system …
B Gran, GX Zhang, S Yu, J Li, XH Chen, ES Ventura, M Kamoun, ...
The Journal of Immunology 169 (12), 7104-7110, 2002
Induction of experimental autoimmune encephalomyelitis in IL-12 receptor-β2-deficient mice: IL-12 responsiveness is not required in the pathogenesis of inflammatory …
GX Zhang, B Gran, S Yu, J Li, I Siglienti, X Chen, M Kamoun, A Rostami
The Journal of Immunology 170 (4), 2153-2160, 2003
Suppressive effect of IL-27 on encephalitogenic Th17 cells and the effector phase of experimental autoimmune encephalomyelitis
DC Fitzgerald, B Ciric, T Touil, H Harle, J Grammatikopolou, JD Sarma, ...
The Journal of Immunology 179 (5), 3268-3275, 2007
IDO upregulates regulatory T cells via tryptophan catabolite and suppresses encephalitogenic T cell responses in experimental autoimmune encephalomyelitis
Y Yan, GX Zhang, B Gran, F Fallarino, S Yu, H Li, ML Cullimore, ...
The Journal of Immunology 185 (10), 5953-5961, 2010
Effect of natalizumab on disease progression in secondary progressive multiple sclerosis (ASCEND): a phase 3, randomised, double-blind, placebo-controlled trial with an open …
R Kapoor, PR Ho, N Campbell, I Chang, A Deykin, F Forrestal, N Lucas, ...
The Lancet Neurology 17 (5), 405-415, 2018
Fatigue in multiple sclerosis—a brief review
I Induruwa, CS Constantinescu, B Gran
Journal of the neurological sciences 323 (1-2), 9-15, 2012
Identification of candidate T-cell epitopes and molecular mimics in chronic Lyme disease
B Hemmer, B Gran, Y Zhao, A Marques, J Pascal, A Tzou, T Kondo, ...
Nature medicine 5 (12), 1375-1382, 1999
Handbook of neurochemistry and molecular neurobiology: neuroimmunology
A Lajtha, A Galoyan, H Besedovsky
Springer Science & Business Media, 2007
Mechanisms of immunomodulation by glatiramer acetate
B Gran, LR Tranquill, M Chen, B Bielekova, W Zhou, S Dhib–Jalbut, ...
Neurology 55 (11), 1704-1714, 2000
TLR2 stimulation drives human naive and effector regulatory T cells into a Th17-like phenotype with reduced suppressive function
MH Nyirenda, L Sanvito, PJ Darlington, K O’Brien, GX Zhang, ...
The Journal of Immunology 187 (5), 2278-2290, 2011
Increased IL-23p19 expression in multiple sclerosis lesions and its induction in microglia
Y Li, N Chu, A Hu, B Gran, A Rostami, GX Zhang
Brain 130 (2), 490-501, 2007
Multiple sclerosis-associated IL2RA polymorphism controls GM-CSF production in human TH cells
FJ Hartmann, M Khademi, J Aram, S Ammann, I Kockum, ...
Nature communications 5 (1), 5056, 2014
Cutting edge: predictable TCR antigen recognition based on peptide scans leads to the identification of agonist ligands with no sequence homology
B Hemmer, M Vergelli, B Gran, N Ling, P Conlon, C Pinilla, R Houghten, ...
The Journal of Immunology 160 (8), 3631-3636, 1998
EAE: imperfect but useful models of multiple sclerosis
A Bert, B Gran, R Weissert
Trends in molecular medicine 17 (3), 119-125, 2011
Cutting edge: TLR3 stimulation suppresses experimental autoimmune encephalomyelitis by inducing endogenous IFN-β
T Touil, D Fitzgerald, GX Zhang, A Rostami, B Gran
The Journal of Immunology 177 (11), 7505-7509, 2006
Molecular mimicry and multiple sclerosis: Degenerate T‐cell recognition and the induction of autoimmunity
B Gran, B Hemmer, M Vergelli, HF McFarland, R Martin
Annals of Neurology: Official Journal of the American Neurological …, 1999
Glatiramer acetate induces a Th2-biased response and crossreactivity with myelin basic protein in patients with MS
M Chen, B Gran, K Costello, K Johnson, R Martin, S Dhib-Jalbut
Multiple Sclerosis Journal 7 (4), 209-219, 2001
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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