| Status of GPCR Modeling and Docking as Reflected by Community-wide GPCR Dock 2010 Assessment I Kufareva, M Rueda, V Katritch, RC Stevens, R Abagyan, Y Yoshikawa, ... Structure 19 (8), 1108-1126, 2011 | 345 | 2011 |
| The role of kinetic context in apparent biased agonism at GPCRs C Klein Herenbrink, DA Sykes, P Donthamsetti, M Canals, T Coudrat, ... Nature communications 7 (1), 10842, 2016 | 320 | 2016 |
| A new mechanism of allostery in a G protein–coupled receptor dimer JR Lane, P Donthamsetti, J Shonberg, CJ Draper-Joyce, S Dentry, ... Nature chemical biology 10 (9), 745-752, 2014 | 125 | 2014 |
| Design strategies for bivalent ligands targeting GPCRs J Shonberg, PJ Scammells, B Capuano ChemMedChem 6 (6), 963-974, 2011 | 122 | 2011 |
| Biased agonism at G protein‐coupled receptors: the promise and the challenges—a medicinal chemistry perspective J Shonberg, L Lopez, PJ Scammells, A Christopoulos, B Capuano, ... Medicinal research reviews 34 (6), 1286-1330, 2014 | 120 | 2014 |
| Homology modeling and docking evaluation of aminergic G protein-coupled receptors FM McRobb, B Capuano, IT Crosby, DK Chalmers, E Yuriev Journal of chemical information and modeling 50 (4), 626-637, 2010 | 112 | 2010 |
| A structure–activity analysis of biased agonism at the dopamine D2 receptor J Shonberg, CK Herenbrink, L Lopez, A Christopoulos, PJ Scammells, ... Journal of medicinal chemistry 56 (22), 9199-9221, 2013 | 103 | 2013 |
| Schizophrenia: genesis, receptorology and current therapeutics B Capuano, IT Crosby, EJ Lloyd Current medicinal chemistry 9 (5), 521-548, 2002 | 99 | 2002 |
| Progress toward the development of noscapine and derivatives as anticancer agents A DeBono, B Capuano, PJ Scammells Journal of medicinal chemistry 58 (15), 5699-5727, 2015 | 97 | 2015 |
| Structure–Activity Relationships of Privileged Structures Lead to the Discovery of Novel Biased Ligands at the Dopamine D2 Receptor M Szabo, C Klein Herenbrink, A Christopoulos, JR Lane, B Capuano Journal of medicinal chemistry 57 (11), 4924-4939, 2014 | 88 | 2014 |
| Synthesis and Pharmacological Profiling of Analogues of Benzyl Quinolone Carboxylic Acid (BQCA) as Allosteric Modulators of the M1 Muscarinic Receptor SN Mistry, C Valant, PM Sexton, B Capuano, A Christopoulos, ... Journal of medicinal chemistry 56 (12), 5151-5172, 2013 | 75 | 2013 |
| Synthesis and Pharmacological Evaluation of Dual Acting Ligands Targeting the Adenosine A2A and Dopamine D2 Receptors for the Potential Treatment of … M Jörg, LT May, FS Mak, KCK Lee, ND Miller, PJ Scammells, ... Journal of medicinal chemistry 58 (2), 718-738, 2015 | 58 | 2015 |
| Homobivalent ligands of the atypical antipsychotic clozapine: design, synthesis, and pharmacological evaluation FM McRobb, IT Crosby, E Yuriev, JR Lane, B Capuano Journal of medicinal chemistry 55 (4), 1622-1634, 2012 | 57 | 2012 |
| Platensimycin: a promising antimicrobial targeting fatty acid synthesis DT Manallack, IT Crosby, Y Khakham, B Capuano Current medicinal chemistry 15 (7), 705-710, 2008 | 57 | 2008 |
| Discovery of a Novel Class of Negative Allosteric Modulator of the Dopamine D2 Receptor Through Fragmentation of a Bitopic Ligand SN Mistry, J Shonberg, CJ Draper-Joyce, C Klein Herenbrink, M Michino, ... Journal of medicinal chemistry 58 (17), 6819-6843, 2015 | 54 | 2015 |
| Synthesis and Biological Evaluation of N‐Substituted Noscapine Analogues AJ DeBono, JH Xie, S Ventura, CW Pouton, B Capuano, PJ Scammells ChemMedChem 7 (12), 2122-2133, 2012 | 54 | 2012 |
| Structure–Activity Study of N-((trans)-4-(2-(7-Cyano-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)cyclohexyl)-1H-indole-2-carboxamide (SB269652), a Bitopic Ligand That Acts as a … J Shonberg, C Draper-Joyce, SN Mistry, A Christopoulos, PJ Scammells, ... Journal of Medicinal Chemistry 58 (13), 5287-5307, 2015 | 45 | 2015 |
| Synthesis and Preliminary Pharmacological Evaluation of 4´-Arylmethyl Analogues of Clozapine. I. The Effect of Aromatic Substituents B Capuano, IT Crosby, EJ Lloyd, DA Taylor Australian journal of chemistry 55 (9), 565-576, 2002 | 45 | 2002 |
| Crossword puzzles for chemistry education: learning goals beyond vocabulary E Yuriev, B Capuano, JL Short Chemistry education research and practice 17 (3), 532-554, 2016 | 41 | 2016 |
| The dopamine D2 and adenosine A2A receptors: past, present and future trends for the treatment of Parkinson's disease M Jorg, PJ Scammells, B Capuano Current medicinal chemistry 21 (27), 3188-3210, 2014 | 40 | 2014 |
