Unraveling comparative anti-amyloidogenic behavior of pyrazinamide and D-cycloserine: a mechanistic biophysical insight SK Chaturvedi, N Zaidi, P Alam, JM Khan, A Qadeer, IA Siddique, ... PloS one 10 (8), e0136528, 2015 | 85 | 2015 |
CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson’s disease Nature Communication, 2020 | 47 | 2020 |
Inhibitory growth evaluation and apoptosis induction in MCF-7 cancer cells by new 5-aryl-2-butylthio-1, 3, 4-oxadiazole derivatives R Khanam, K Ahmad, II Hejazi, IA Siddique, V Kumar, AR Bhat, A Azam, ... Cancer Chemotherapy and Pharmacology 80, 1027-1042, 2017 | 28 | 2017 |
Molecular basis of the inhibition and disaggregation of thermally-induced amyloid fibrils of human serum albumin by an anti-Parkinson's drug, benserazide hydrochloride TI Chandel, A Masroor, MK Siddiqi, IA Siddique, I Jahan, M Ali, ... Journal of Molecular Liquids 278, 553-567, 2019 | 25 | 2019 |
mTOR inhibition with Sirolimus in multiple system atrophy: a randomized, double‐blind, placebo‐controlled futility trial and 1‐year biomarker longitudinal analysis JA Palma, J Martinez, P Millar Vernetti, T Ma, MA Perez, J Zhong, Y Qian, ... Movement Disorders 37 (4), 778-789, 2022 | 19 | 2022 |
The molecular tweezer CLR01 improves behavioral deficits and reduces tau pathology in P301S-tau transgenic mice J Di, I Siddique, Z Li, G Malki, S Hornung, S Dutta, I Hurst, E Ishaaya, ... Alzheimer's research & therapy 13, 1-20, 2021 | 19 | 2021 |
Anti-parkinsonian l-dopa can also act as anti-systemic amyloidosis—A mechanistic exploration S Nusrat, N Zaidi, MK Siddiqi, M Zaman, IA Siddique, MR Ajmal, ... International journal of biological macromolecules 99, 630-640, 2017 | 18 | 2017 |
An insight into the inhibition of fibrillation process verses disaggregation of preformed fibrils of bovine serum albumin by isoprenaline hydrochloride TI Chandel, M Afghani, A Masroor, IA Siddique, SM Zakariya, M Ali, ... International journal of biological macromolecules 154, 1448-1459, 2020 | 16 | 2020 |
Development of a Novel Electrochemiluminescence ELISA for Quantification of α-Synuclein Phosphorylated at Ser129 in Biological Samples S Dutta, S Hornung, HB Taha, K Biggs, I Siddique, LM Chamoun, ... ACS Chemical Neuroscience 14 (7), 1238-1248, 2023 | 15 | 2023 |
A multiparametric analysis of the synergistic impact of anti-Parkinson's drugs on the fibrillation of human serum albumin TI Chandel, N Zaidi, M Zaman, I Jahan, A Masroor, IA Siddique, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1867 (3), 275-285, 2019 | 15 | 2019 |
A routinely used protein staining dye acts as an inhibitor of wild type and mutant alpha-synuclein aggregation and modulator of neurotoxicity N Ahsan, IA Siddique, S Gupta, A Surolia European Journal of Medicinal Chemistry 143, 1174-1184, 2018 | 14 | 2018 |
Prion protein transcription is auto-regulated through dynamic interactions with G-quadruplex motifs in its own promoter P Pradhan, A Srivastava, J Singh, B Biswas, A Saini, I Siddique, P Kumari, ... Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1863 (3), 194479, 2020 | 11 | 2020 |
Lysine-selective molecular tweezers are cell penetrant and concentrate in lysosomes Z Li, I Siddique, I Hadrović, A Kirupakaran, J Li, Y Zhang, FG Klärner, ... Communications biology 4 (1), 1076, 2021 | 9 | 2021 |
Molecular tweezers: supramolecular hosts with broad-spectrum biological applications H Shahpasand-Kroner, I Siddique, R Malik, GR Linares, MI Ivanova, ... Pharmacological Reviews 75 (2), 263-308, 2023 | 8 | 2023 |
Exophers are components of mammalian cell neurobiology in health and disease I Siddique, J Di, CK Williams, D Markovic, HV Vinters, G Bitan bioRxiv, 2021.12. 06.471479, 2021 | 7 | 2021 |
ARL6IP5 Ameliorates α-Synuclein Burden by Inducing Autophagy via Preventing Ubiquitination and Degradation of ATG12 I Siddique, K Kamble, S Gupta, K Solanki, S Bhola, N Ahsan, S Gupta International Journal of Molecular Sciences 24 (13), 10499, 2023 | 3 | 2023 |
Different inhibitors of Aβ42-induced toxicity have distinct metal-ion dependency AJ Mason, I Hurst, R Malik, I Siddique, I Solomonov, I Sagi, FG Klärner, ... ACS chemical neuroscience 11 (15), 2243-2255, 2020 | 2 | 2020 |
New blood-based biomarkers for Sanfilippo syndrome G Bitan, HB Taha, I Siddique, LM Chamoun, K Mohseni, AJ Morris, ... Molecular Genetics and Metabolism 141 (2), 107775, 2024 | | 2024 |
COMPOUND MODULATING GSK-3 ACTIVITY Sarika Gupta, Ibrar Siddique, Aishwarya Nilakhe US Patent US, 11,820,764 B2, 2023 | | 2023 |
Carboxylated osteocalcin for treatment of amyloidosis or diseases associated with abnormal protein folding S Gupta, V Vijayan, IA Siddique US Patent App. 17/051,272, 2022 | | 2022 |