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henk-jan guchelaar
henk-jan guchelaar
Leiden University Medical center
Email verificata su lumc.nl - Home page
Titolo
Citata da
Citata da
Anno
Genetics of rheumatoid arthritis contributes to biology and drug discovery
Y Okada, D Wu, G Trynka, T Raj, C Terao, K Ikari, Y Kochi, K Ohmura, ...
Nature 506 (7488), 376-381, 2014
24112014
Pharmacogenetics: from bench to byte—an update of guidelines
JJ Swen, M Nijenhuis, A de Boer, L Grandia, AH Maitland‐van der Zee, ...
Clinical Pharmacology & Therapeutics 89 (5), 662-673, 2011
11922011
Flucytosine: a review of its pharmacology, clinical indications, pharmacokinetics, toxicity and drug interactions
A Vermes, HJ Guchelaar, J Dankert
Journal of Antimicrobial Chemotherapy 46 (2), 171-179, 2000
8892000
The risk of cancer in users of statins
MR Graaf, AB Beiderbeck, ACG Egberts, DJ Richel, HJ Guchelaar
Journal of clinical oncology 22 (12), 2388-2394, 2004
6172004
Cardiotoxicity of cytotoxic drugs
KJM Schimmel, DJ Richel, RBA Van den Brink, HJ Guchelaar
Cancer treatment reviews 30 (2), 181-191, 2004
5482004
Clinical pharmacokinetics of tyrosine kinase inhibitors
NP van Erp, H Gelderblom, HJ Guchelaar
Cancer treatment reviews 35 (8), 692-706, 2009
4692009
Recent insights in the pharmacological actions of methotrexate in the treatment of rheumatoid arthritis
JAM Wessels, TWJ Huizinga, HJ Guchelaar
Rheumatology 47 (3), 249-255, 2008
4252008
Standardizing CYP2D6 Genotype to Phenotype Translation: Consensus Recommendations from the Clinical Pharmacogenetics Implementation Consortium and …
KE Caudle, K Sangkuhl, M Whirl‐Carrillo, JJ Swen, CE Haidar, TE Klein, ...
Clinical and translational science 13 (1), 116-124, 2020
4222020
Effects of statins and farnesyltransferase inhibitors on the development and progression of cancer
MR Graaf, DJ Richel, CJF van Noorden, HJ Guchelaar
Cancer treatment reviews 30 (7), 609-641, 2004
3662004
DPYD genotype-guided dose individualisation of fluoropyrimidine therapy in patients with cancer: a prospective safety analysis
LM Henricks, CATC Lunenburg, FM de Man, D Meulendijks, ...
The Lancet Oncology 19 (11), 1459-1467, 2018
3272018
Making sense of big data in health research: towards an EU action plan
C Auffray, R Balling, I Barroso, L Bencze, M Benson, J Bergeron, ...
Genome medicine 8, 1-13, 2016
3222016
Liposomal drug formulations in cancer therapy: 15 years along the road
M Slingerland, HJ Guchelaar, H Gelderblom
Drug discovery today 17 (3-4), 160-166, 2012
3112012
A clinical pharmacogenetic model to predict the efficacy of methotrexate monotherapy in recent‐onset rheumatoid arthritis
JAM Wessels, SM van der Kooij, S le Cessie, W Kievit, P Barerra, ...
Arthritis & Rheumatism 56 (6), 1765-1775, 2007
2972007
Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single‐nucleotide polymorphisms in genes coding for folate pathway enzymes
JAM Wessels, JK de Vries‐Bouwstra, BT Heijmans, PE Slagboom, ...
Arthritis & Rheumatism 54 (4), 1087-1095, 2006
2962006
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and Tamoxifen Therapy
MP Goetz, K Sangkuhl, HJ Guchelaar, M Schwab, M Province, ...
Clinical Pharmacology & Therapeutics 103 (5), 770-777, 2018
2942018
Implementing pharmacogenomics in Europe: design and implementation strategy of the ubiquitous pharmacogenomics consortium
CH van der Wouden, A Cambon‐Thomsen, E Cecchin, KC Cheung, ...
Clinical Pharmacology & Therapeutics 101 (3), 341-358, 2017
2872017
Pharmacogenetics: from bench to byte
JJ Swen, I Wilting, AL De Goede, L Grandia, H Mulder, DJ Touw, ...
Clinical pharmacology & therapeutics 83 (5), 781-787, 2008
2872008
Radiation-induced xerostomia: pathophysiology, clinical course and supportive treatment
HJ Guchelaar, A Vermes, JH Meerwaldt
Supportive care in cancer 5, 281-288, 1997
2501997
Relationship between Single Nucleotide Polymorphisms and Haplotypes in DPYD and Toxicity and Efficacy of Capecitabine in Advanced Colorectal Cancer
MJ Deenen, J Tol, AM Burylo, VD Doodeman, A De Boer, A Vincent, ...
Clinical Cancer Research 17 (10), 3455-3468, 2011
2452011
Pharmacogenetic pathway analysis for determination of sunitinib-induced toxicity
NP van Erp, K Eechoute, AA van der Veldt, JB Haanen, AK Reyners, ...
J Clin Oncol 27 (26), 4406-12, 2009
2372009
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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