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Byron Au-Yeung
Byron Au-Yeung
Assistant Professor, Department of Medicine, Emory University
Verified email at emory.edu
Title
Cited by
Cited by
Year
ZAP-70: an essential kinase in T-cell signaling
H Wang, TA Kadlecek, BB Au-Yeung, HES Goodfellow, LY Hsu, ...
Cold Spring Harbor perspectives in biology 2 (5), 2010
4552010
The structure, regulation, and function of ZAP‐70
BB Au‐Yeung, S Deindl, LY Hsu, EH Palacios, SE Levin, J Kuriyan, ...
Immunological reviews 228 (1), 41-57, 2009
2602009
Extrathymic Aire-expressing cells are a distinct bone marrow-derived population that induce functional inactivation of CD4+ T cells
JM Gardner, TC Metzger, EJ McMahon, BB Au-Yeung, AK Krawisz, W Lu, ...
Immunity 39 (3), 560-572, 2013
1712013
A sharp T-cell antigen receptor signaling threshold for T-cell proliferation
BB Au-Yeung, J Zikherman, JL Mueller, JF Ashouri, M Matloubian, ...
Proceedings of the National Academy of Sciences 111 (35), E3679-E3688, 2014
1632014
ZAP-70 in signaling, biology, and disease
BB Au-Yeung, NH Shah, L Shen, A Weiss
Annual review of immunology 36, 127-156, 2018
1362018
IL-2 modulates the TCR signaling threshold for CD8 but not CD4 T cell proliferation on a single-cell level
BB Au-Yeung, GA Smith, JL Mueller, CS Heyn, RG Jaszczak, A Weiss, ...
The Journal of Immunology 198 (6), 2445-2456, 2017
1242017
A genetically selective inhibitor demonstrates a function for the kinase Zap70 in regulatory T cells independent of its catalytic activity
BB Au-Yeung, SE Levin, C Zhang, LY Hsu, DA Cheng, N Killeen, ...
Nature immunology 11 (12), 1085-1092, 2010
1222010
A key role for Itk in both IFNγ and IL-4 production by NKT cells
BB Au-Yeung, DJ Fowell
The Journal of Immunology 179 (1), 111-119, 2007
852007
Cutting edge: Itk-dependent signals required for CD4+ T cells to exert, but not gain, Th2 effector function
BB Au-Yeung, SD Katzman, DJ Fowell
The Journal of Immunology 176 (7), 3895-3899, 2006
852006
Monovalent and multivalent ligation of the B cell receptor exhibit differential dependence upon Syk and Src family kinases
S Mukherjee, J Zhu, J Zikherman, R Parameswaran, TA Kadlecek, ...
Science signaling 6 (256), ra1-ra1, 2013
842013
Quantitative and temporal requirements revealed for Zap70 catalytic activity during T cell development
BB Au-Yeung, HJ Melichar, JO Ross, DA Cheng, J Zikherman, KM Shokat, ...
Nature immunology 15 (7), 687-694, 2014
722014
Distinct phases in the positive selection of CD8+ T cells distinguished by intrathymic migration and T-cell receptor signaling patterns
JO Ross, HJ Melichar, BB Au-Yeung, P Herzmark, A Weiss, EA Robey
Proceedings of the National Academy of Sciences 111 (25), E2550-E2558, 2014
702014
A phosphosite within the SH2 domain of Lck regulates its activation by CD45
AH Courtney, JF Amacher, TA Kadlecek, MN Mollenauer, BB Au-Yeung, ...
Molecular cell 67 (3), 498-511. e6, 2017
612017
Itk controls the spatiotemporal organization of T cell activation
KL Singleton, M Gosh, RD Dandekar, BB Au-Yeung, O Ksionda, ...
Science signaling 4 (193), ra66-ra66, 2011
582011
The role of T cell receptor signaling thresholds in guiding T cell fate decisions
J Zikherman, B Au-Yeung
Current opinion in immunology 33, 43-48, 2015
562015
Pak2 is required for actin cytoskeleton remodeling, TCR signaling, and normal thymocyte development and maturation
H Phee, BB Au-Yeung, O Pryshchep, KL O'Hagan, SG Fairbairn, M Radu, ...
Elife 3, e02270, 2014
552014
Adaptation by naïve CD4+ T cells to self-antigen–dependent TCR signaling induces functional heterogeneity and tolerance
WM Zinzow-Kramer, A Weiss, BB Au-Yeung
Proceedings of the National Academy of Sciences 116 (30), 15160-15169, 2019
542019
Distinct structural and catalytic roles for Zap70 in formation of the immunological synapse in CTL
MR Jenkins, JC Stinchcombe, BB Au-Yeung, Y Asano, AT Ritter, A Weiss, ...
Elife 3, e01310, 2014
512014
CIP2A Promotes T-Cell Activation and Immune Response to Listeria monocytogenes Infection
C Come, A Cvrljevic, MM Khan, I Treise, T Adler, JA Aguilar-Pimentel, ...
PLoS One 11 (4), e0152996, 2016
172016
Functional heterogeneity and adaptation of naive T cells in response to tonic TCR signals
J Eggert, BB Au-Yeung
Current opinion in immunology 73, 43-49, 2021
112021
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