Wyatt Travis Clark
Wyatt Travis Clark
Senior Scientist, BioMarin
Email verificata su bmrn.com - Home page
Citata da
Citata da
A large-scale evaluation of computational protein function prediction
P Radivojac, WT Clark, TR Oron, AM Schnoes, T Wittkop, A Sokolov, ...
Nature methods 10 (3), 221-227, 2013
An expanded evaluation of protein function prediction methods shows an improvement in accuracy
Y Jiang, TR Oron, WT Clark, AR Bankapur, D D’Andrea, R Lepore, ...
Genome biology 17 (1), 1-19, 2016
An integrated approach to inferring gene–disease associations in humans
P Radivojac, K Peng, WT Clark, BJ Peters, A Mohan, SM Boyle, ...
Proteins: Structure, Function, and Bioinformatics 72 (3), 1030-1037, 2008
Testing the ortholog conjecture with comparative functional genomic data from mammals
NL Nehrt, WT Clark, P Radivojac, MW Hahn
PLoS Comput Biol 7 (6), e1002073, 2011
Analysis of protein function and its prediction from amino acid sequence
WT Clark, P Radivojac
Proteins: Structure, Function, and Bioinformatics 79 (7), 2086-2096, 2011
Information-theoretic evaluation of predicted ontological annotations
WT Clark, P Radivojac
Bioinformatics 29 (13), i53-i61, 2013
Analysis of deletion breakpoints from 1,092 humans reveals details of mutation mechanisms
A Abyzov, S Li, DR Kim, M Mohiyuddin, AM Stütz, NF Parrish, XJ Mu, ...
Nature communications 6 (1), 1-12, 2015
Comparative analysis of pseudogenes across three phyla
C Sisu, B Pei, J Leng, A Frankish, Y Zhang, S Balasubramanian, R Harte, ...
Proceedings of the National Academy of Sciences 111 (37), 13361-13366, 2014
The impact of incomplete knowledge on the evaluation of protein function prediction: a structured-output learning perspective
Y Jiang, WT Clark, I Friedberg, P Radivojac
Bioinformatics 30 (17), i609-i616, 2014
Using compression to identify classes of inauthentic texts
MM Dalkilic, WT Clark, JC Costello, P Radivojac
Proceedings of the 2006 SIAM International Conference on Data Mining, 604-608, 2006
Prediction of functional regulatory SNPs in monogenic and complex disease
Y Zhao, WT Clark, M Mort, DN Cooper, P Radivojac, SD Mooney
Human mutation 32 (10), 1183-1190, 2011
From protein-disease associations to disease informatics
MM Dalkilic, JC Costello, WT Clark, P Radivojac
Front Biosci 13, 3391-3407, 2008
Characterization of glycan substrates accumulating in GM1 Gangliosidosis
R Lawrence, JL Van Vleet, L Mangini, A Harris, N Martin, W Clark, ...
Molecular genetics and metabolism reports 21, 100524, 2019
Vector quantization kernels for the classification of protein sequences and structures
WT Clark, P Radivojac
Biocomputing 2014, 316-327, 2014
Utilizing ExAC to assess the hidden contribution of variants of unknown significance to Sanfilippo Type B incidence
WT Clark, GK Yu, M Aoyagi-Scharber, JH LeBowitz
Plos one 13 (7), e0200008, 2018
Identifying therapeutic drug targets for rare and common forms of short stature
K Estrada, S Froelich, A Wuster, CR Bauer, T Sterling, WT Clark, Y Ru, ...
bioRxiv, 2020
Assessment of predicted enzymatic activity of α‐N‐acetylglucosaminidase variants of unknown significance for CAGI 2016
WT Clark, L Kasak, C Bakolitsa, Z Hu, G Andreoletti, G Babbi, Y Bromberg, ...
Human mutation 40 (9), 1519-1529, 2019
Understanding protein function through statistical inference and evolutionary analysis
W Clark
PhD thesis, School of Informatics and Computing, Indiana University, Indiana …, 2013
Identifying therapeutic drug targets using bidirectional effect genes
K Estrada, S Froelich, A Wuster, CR Bauer, T Sterling, WT Clark, Y Ru, ...
Nature Communications 12 (1), 1-11, 2021
Utilizing activity assays and population-wide allele frequencies to assess the contribution of novel mutations in NAGLU to MPS IIIB incidence
JH LeBowitz, WT Clark, GK Yu, M Aoyagi-Scharber
Molecular Genetics and Metabolism 2 (117), S72, 2016
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