Enzo Medico
Enzo Medico
Professor of Histology, University of Torino and Head of the Laboratory of Oncogenomics, Candiolo
Verified email at ircc.it
TitleCited byYear
Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer
S Misale, R Yaeger, S Hobor, E Scala, M Janakiraman, D Liska, E Valtorta, ...
Nature 486 (7404), 532, 2012
13132012
A molecularly annotated platform of patient-derived xenografts (“xenopatients”) identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer
A Bertotti, G Migliardi, F Galimi, F Sassi, D Torti, C Isella, D Corà, ...
Cancer discovery 1 (6), 508-523, 2011
6052011
Expression of the Met/HGF receptor in normal and neoplastic human tissues.
MFR Di, RP Narsimhan, M Olivero, S Bretti, S Giordano, E Medico, ...
Oncogene 6 (11), 1997-2003, 1991
5871991
Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients
G Siravegna, B Mussolin, M Buscarino, G Corti, A Cassingena, ...
Nature medicine 21 (7), 795, 2015
5422015
FLAME, a novel fuzzy clustering method for the analysis of DNA microarray data
L Fu, E Medico
BMC bioinformatics 8 (1), 3, 2007
4242007
Stromal contribution to the colorectal cancer transcriptome
C Isella, A Terrasi, SE Bellomo, C Petti, G Galatola, A Muratore, A Mellano, ...
Nature genetics 47 (4), 312, 2015
3242015
The MET oncogene drives a genetic programme linking cancer to haemostasis
C Boccaccio, G Sabatino, E Medico, F Girolami, A Follenzi, G Reato, ...
Nature 434 (7031), 396, 2005
2672005
Induction of MET by ionizing radiation and its role in radioresistance and invasive growth of cancer
F De Bacco, P Luraghi, E Medico, G Reato, F Girolami, T Perera, ...
JNCI: Journal of the National Cancer Institute 103 (8), 645-661, 2011
2562011
Interrogating open issues in cancer precision medicine with patient-derived xenografts
AT Byrne, DG Alférez, F Amant, D Annibali, J Arribas, AV Biankin, A Bruna, ...
Nature Reviews Cancer 17 (4), 254, 2017
2182017
Promoter trapping reveals significant differences in integration site selection between MLV and HIV vectors in primary hematopoietic cells
M De Palma, E Montini, FRS De Sio, F Benedicenti, A Gentile, E Medico, ...
Blood 105 (6), 2307-2315, 2005
1962005
Neural differentiation of human mesenchymal stem cells: Evidence for expression of neural markers and eag K+ channel types
K Mareschi, M Novara, D Rustichelli, I Ferrero, D Guido, E Carbone, ...
Experimental hematology 34 (11), 1563-1572, 2006
1952006
Transfer of motogenic and invasive response to scatter factor/hepatocyte growth factor by transfection of human MET protooncogene.
S Giordano, Z Zhen, E Medico, G Gaudino, F Galimi, PM Comoglio
Proceedings of the National Academy of Sciences 90 (2), 649-653, 1993
1651993
The tyrosine kinase receptors Ron and Sea control" scattering" and morphogenesis of liver progenitor cells in vitro.
E Medico, AM Mongiovi, J Huff, MA Jelinek, A Follenzi, G Gaudino, ...
Molecular biology of the cell 7 (4), 495-504, 1996
1581996
Phosphorylation of serine 985 negatively regulates the hepatocyte growth factor receptor kinase.
L Gandino, P Longati, E Medico, M Prat, PM Comoglio
Journal of Biological Chemistry 269 (3), 1815-1820, 1994
1471994
Gene expression profiling uncovers molecular classifiers for the recognition of anaplastic large-cell lymphoma within peripheral T-cell neoplasms
R Piva, L Agnelli, E Pellegrino, K Todoerti, V Grosso, I Tamagno, ...
J Clin Oncol 28 (9), 1583-1590, 2010
1422010
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets
E Medico, M Russo, G Picco, C Cancelliere, E Valtorta, G Corti, ...
Nature communications 6, 7002, 2015
1342015
The MET oncogene is a functional marker of a glioblastoma stem cell subtype
F De Bacco, E Casanova, E Medico, S Pellegatta, F Orzan, R Albano, ...
Cancer research 72 (17), 4537-4550, 2012
1182012
Genetic and expression analysis of MET, MACC1, and HGF in metastatic colorectal cancer: response to met inhibition in patient xenografts and pathologic correlations
F Galimi, D Torti, F Sassi, C Isella, D Corà, S Gastaldi, D Ribero, ...
Clinical cancer research 17 (10), 3146-3156, 2011
1122011
The thioxotriazole copper (II) complex A0 induces endoplasmic reticulum stress and paraptotic death in human cancer cells
S Tardito, C Isella, E Medico, L Marchio, E Bevilacqua, M Hatzoglou, ...
Journal of Biological Chemistry 284 (36), 24306-24319, 2009
1092009
Osteopontin is an autocrine mediator of hepatocyte growth factor-induced invasive growth
E Medico, A Gentile, CL Celso, TA Williams, G Gambarotta, L Trusolino, ...
Cancer research 61 (15), 5861-5868, 2001
1072001
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