Enzo Medico
Enzo Medico
Professor of Histology, University of Torino and Head of the Laboratory of Oncogenomics, Candiolo
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Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer
S Misale, R Yaeger, S Hobor, E Scala, M Janakiraman, D Liska, E Valtorta, ...
Nature 486 (7404), 532-536, 2012
Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients
G Siravegna, B Mussolin, M Buscarino, G Corti, A Cassingena, ...
Nature medicine 21 (7), 795-801, 2015
A molecularly annotated platform of patient-derived xenografts (“xenopatients”) identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer
A Bertotti, G Migliardi, F Galimi, F Sassi, D Torti, C Isella, D Corŕ, ...
Cancer discovery 1 (6), 508-523, 2011
Expression of the Met/HGF receptor in normal and neoplastic human tissues.
MF Di Renzo, RP Narsimhan, M Olivero, S Bretti, S Giordano, E Medico, ...
Oncogene 6 (11), 1997-2003, 1991
Interrogating open issues in cancer precision medicine with patient-derived xenografts
AT Byrne, DG Alférez, F Amant, D Annibali, J Arribas, AV Biankin, A Bruna, ...
Nature Reviews Cancer 17 (4), 254-268, 2017
Stromal contribution to the colorectal cancer transcriptome
C Isella, A Terrasi, SE Bellomo, C Petti, G Galatola, A Muratore, A Mellano, ...
Nature genetics 47 (4), 312-319, 2015
FLAME, a novel fuzzy clustering method for the analysis of DNA microarray data
L Fu, E Medico
BMC bioinformatics 8 (1), 1-15, 2007
Induction of MET by ionizing radiation and its role in radioresistance and invasive growth of cancer
F De Bacco, P Luraghi, E Medico, G Reato, F Girolami, T Perera, ...
JNCI: Journal of the National Cancer Institute 103 (8), 645-661, 2011
The MET oncogene drives a genetic programme linking cancer to haemostasis
C Boccaccio, G Sabatino, E Medico, F Girolami, A Follenzi, G Reato, ...
Nature 434 (7031), 396-400, 2005
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets
E Medico, M Russo, G Picco, C Cancelliere, E Valtorta, G Corti, ...
Nature communications 6 (1), 7002, 2015
Selective analysis of cancer-cell intrinsic transcriptional traits defines novel clinically relevant subtypes of colorectal cancer
C Isella, F Brundu, SE Bellomo, F Galimi, E Zanella, R Porporato, C Petti, ...
Nature communications 8 (1), 15107, 2017
Neural differentiation of human mesenchymal stem cells: Evidence for expression of neural markers and eag K+ channel types
K Mareschi, M Novara, D Rustichelli, I Ferrero, D Guido, E Carbone, ...
Experimental hematology 34 (11), 1563-1572, 2006
Increased lactate secretion by cancer cells sustains non-cell-autonomous adaptive resistance to MET and EGFR targeted therapies
M Apicella, E Giannoni, S Fiore, KJ Ferrari, D Fernández-Pérez, C Isella, ...
Cell metabolism 28 (6), 848-865. e6, 2018
Promoter trapping reveals significant differences in integration site selection between MLV and HIV vectors in primary hematopoietic cells
M De Palma, E Montini, FRS de Sio, F Benedicenti, A Gentile, E Medico, ...
Blood 105 (6), 2307-2315, 2005
Phosphorylation of serine 985 negatively regulates the hepatocyte growth factor receptor kinase.
L Gandino, P Longati, E Medico, M Prat, PM Comoglio
Journal of Biological Chemistry 269 (3), 1815-1820, 1994
Transfer of motogenic and invasive response to scatter factor/hepatocyte growth factor by transfection of human MET protooncogene.
S Giordano, Z Zhen, E Medico, G Gaudino, F Galimi, PM Comoglio
Proceedings of the National Academy of Sciences 90 (2), 649-653, 1993
Gene expression profiling uncovers molecular classifiers for the recognition of anaplastic large-cell lymphoma within peripheral T-cell neoplasms
R Piva, L Agnelli, E Pellegrino, K Todoerti, V Grosso, I Tamagno, ...
J Clin Oncol 28 (9), 1583-1590, 2010
The tyrosine kinase receptors Ron and Sea control" scattering" and morphogenesis of liver progenitor cells in vitro.
E Medico, AM Mongiovi, J Huff, MA Jelinek, A Follenzi, G Gaudino, ...
Molecular biology of the cell 7 (4), 495-504, 1996
The MET Oncogene Is a Functional Marker of a Glioblastoma Stem Cell Subtype
F De Bacco, E Casanova, E Medico, S Pellegatta, F Orzan, R Albano, ...
Cancer research 72 (17), 4537-4550, 2012
The clinical and biological significance of MIR-224 expression in colorectal cancer metastasis
H Ling, K Pickard, C Ivan, C Isella, M Ikuo, R Mitter, R Spizzo, MD Bullock, ...
Gut 65 (6), 977-989, 2016
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