| Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview AH Schinkel, JW Jonker Advanced drug delivery reviews 64, 138-153, 2012 | 2052 | 2012 |
| The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria JW Jonker, M Buitelaar, E Wagenaar, MA Van Der Valk, GL Scheffer, ... Proceedings of the National Academy of Sciences 99 (24), 15649-15654, 2002 | 982 | 2002 |
| Short-chain fatty acids protect against high-fat diet–induced obesity via a PPARγ-dependent switch from lipogenesis to fat oxidation G Den Besten, A Bleeker, A Gerding, K van Eunen, R Havinga, ... Diabetes 64 (7), 2398-2408, 2015 | 925 | 2015 |
| Role of breast cancer resistance protein in the bioavailability and fetal penetration of topotecan JW Jonker, JW Smit, RF Brinkhuis, M Maliepaard, JH Beijnen, ... Journal of the National Cancer Institute 92 (20), 1651-1656, 2000 | 826 | 2000 |
| Cryptochromes mediate rhythmic repression of the glucocorticoid receptor KA Lamia, SJ Papp, RT Yu, GD Barish, NH Uhlenhaut, JW Jonker, ... Nature 480 (7378), 552-556, 2011 | 615 | 2011 |
| Involvement of organic cation transporter 1 in hepatic and intestinal distribution of metformin DS Wang, JW Jonker, Y Kato, H Kusuhara, AH Schinkel, Y Sugiyama Journal of Pharmacology and Experimental Therapeutics 302 (2), 510-515, 2002 | 569 | 2002 |
| The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk JW Jonker, G Merino, S Musters, AE van Herwaarden, E Bolscher, ... Nature medicine 11 (2), 127-129, 2005 | 510 | 2005 |
| Pharmacological and physiological functions of the polyspecific organic cation transporters: OCT1, 2, and 3 (SLC22A1-3) JW Jonker, AH Schinkel Journal of Pharmacology and Experimental Therapeutics 308 (1), 2-9, 2004 | 468 | 2004 |
| ERRγ directs and maintains the transition to oxidative metabolism in the postnatal heart WA Alaynick, RP Kondo, W Xie, W He, CR Dufour, M Downes, JW Jonker, ... Cell metabolism 6 (1), 13-24, 2007 | 355 | 2007 |
| Human breast cancer resistance protein: interactions with steroid drugs, hormones, the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo (4, 5-b) pyridine, and transport of … P Pavek, G Merino, E Wagenaar, E Bolscher, M Novotna, JW Jonker, ... Journal of Pharmacology and Experimental Therapeutics 312 (1), 144-152, 2005 | 322 | 2005 |
| The breast cancer resistance protein (Bcrp1/Abcg2) restricts exposure to the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo [4, 5-b] pyridine AE van Herwaarden, JW Jonker, E Wagenaar, RF Brinkhuis, ... Cancer research 63 (19), 6447-6452, 2003 | 311 | 2003 |
| Abnormal liver function tests in patients with COVID‐19: relevance and potential pathogenesis A Bertolini, IP van De Peppel, FAJA Bodewes, H Moshage, A Fantin, ... Hepatology 72 (5), 1864-1872, 2020 | 308 | 2020 |
| Inhibition of mTORC1 by astrin and stress granules prevents apoptosis in cancer cells K Thedieck, B Holzwarth, MT Prentzell, C Boehlke, K Kläsener, S Ruf, ... Cell 154 (4), 859-874, 2013 | 298 | 2013 |
| Deficiency in the organic cation transporters 1 and 2 (Oct1/Oct2 [Slc22a1/Slc22a2]) in mice abolishes renal secretion of organic cations JW Jonker, E Wagenaar, S Van Eijl, AH Schinkel Molecular and Cellular Biology 23 (21), 7902-7908, 2003 | 298 | 2003 |
| A PPARγ–FGF1 axis is required for adaptive adipose remodelling and metabolic homeostasis JW Jonker, JM Suh, AR Atkins, M Ahmadian, P Li, J Whyte, M He, ... Nature 485 (7398), 391-394, 2012 | 290 | 2012 |
| Reduced Hepatic Uptake and Intestinal Excretion of Organic Cations in Mice with a Targeted Disruption of the Organic Cation Transporter 1 (Oct1 [Slc22a1]) Gene JW Jonker, E Wagenaar, CAAM Mol, M Buitelaar, H Koepsell, JW Smit, ... Molecular and Cellular Biology 21 (16), 5471-5477, 2001 | 286 | 2001 |
| Multidrug Transporter ABCG2/Breast Cancer Resistance Protein Secretes Riboflavin (Vitamin B2) into Milk AE van Herwaarden, E Wagenaar, G Merino, JW Jonker, H Rosing, ... Molecular and cellular biology 27 (4), 1247-1253, 2007 | 285 | 2007 |
| The breast cancer resistance protein (BCRP/ABCG2) affects pharmacokinetics, hepatobiliary excretion, and milk secretion of the antibiotic nitrofurantoin G Merino, JW Jonker, E Wagenaar, AE van Herwaarden, AH Schinkel Molecular pharmacology 67 (5), 1758-1764, 2005 | 275 | 2005 |
| Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer JM Suh, JW Jonker, M Ahmadian, R Goetz, D Lackey, O Osborn, Z Huang, ... Nature 513 (7518), 436-439, 2014 | 265 | 2014 |
| Involvement of organic cation transporter 1 in the lactic acidosis caused by metformin DS Wang, H Kusuhara, Y Kato, JW Jonker, AH Schinkel, Y Sugiyama Molecular pharmacology 63 (4), 844-848, 2003 | 245 | 2003 |
Ronald M EvansProfessor, Salk InstituteVerified email at salk.edu
