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Rafael M. Couñago
Rafael M. Couñago
Centro de Química Medicinal - UNICAMP
Verified email at unicamp.br - Homepage
Title
Cited by
Cited by
Year
Evolution of the B3 DNA binding superfamily: new insights into REM family gene diversification
EAC Romanel, CG Schrago, RM Couñago, CAM Russo, M Alves-Ferreira
PloS one 4 (6), e5791, 2009
1552009
Imperfect coordination chemistry facilitates metal ion release in the Psa permease
RM Couñago, MP Ween, SL Begg, M Bajaj, J Zuegg, ML O'mara, ...
Nature chemical biology 10 (1), 35-41, 2014
1522014
Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniae
SL Begg, BA Eijkelkamp, Z Luo, RM Counago, JR Morey, MJ Maher, ...
Nature communications 6 (1), 6418, 2015
1212015
In vivo molecular evolution reveals biophysical origins of organismal fitness
R Couñago, S Chen, Y Shamoo
Molecular cell 22 (4), 441-449, 2006
1192006
AdcA and AdcAII employ distinct zinc acquisition mechanisms and contribute additively to zinc homeostasis in Streptococcus pneumoniae
CD Plumptre, BA Eijkelkamp, JR Morey, F Behr, RM Couñago, ...
Molecular microbiology 91 (4), 834-851, 2014
1062014
WNT activates the AAK1 kinase to promote clathrin-mediated endocytosis of LRP6 and establish a negative feedback loop
MJ Agajanian, MP Walker, AD Axtman, RR Ruela-de-Sousa, DS Serafin, ...
Cell reports 26 (1), 79-93. e8, 2019
722019
Crystal structure of rice importin-α and structural basis of its interaction with plant-specific nuclear localization signals
CW Chang, RLM Couñago, SJ Williams, M Bodén, B Kobe
The Plant Cell 24 (12), 5074-5088, 2012
712012
Distinctive conformation of minor site‐specific nuclear localization signals bound to importin‐α
CW Chang, RM Couñago, SJ Williams, M Bodén, B Kobe
Traffic 14 (11), 1144-1154, 2013
572013
An adaptive mutation in adenylate kinase that increases organismal fitness is linked to stability–activity trade-offs
R Counago, CJ Wilson, MI Pena, P Wittung-Stafshede, Y Shamoo
Protein Engineering, Design & Selection 21 (1), 19-27, 2008
482008
Gene replacement of adenylate kinase in the gram-positive thermophile Geobacillus stearothermophilus disrupts adenine nucleotide homeostasis and reduces cell …
R Couñago, Y Shamoo
Extremophiles 9, 135-144, 2005
422005
Gene replacement of adenylate kinase in the gram-positive thermophile Geobacillus stearothermophilus disrupts adenine nucleotide homeostasis and reduces cell …
R Couñago, Y Shamoo
Extremophiles 9, 135-144, 2005
422005
A Glutathione-Dependent Detoxification System Is Required for Formaldehyde Resistance and Optimal Survival of Neisseria meningitidis in Biofilms
NH Chen, RM Counago, KY Djoko, MP Jennings, MA Apicella, B Kobe, ...
Antioxidants & redox signaling 18 (7), 743-755, 2013
402013
SGC-AAK1-1: a chemical probe targeting AAK1 and BMP2K
C Wells, RM Counago, JC Limas, TL Almeida, JG Cook, DH Drewry, ...
ACS medicinal chemistry letters 11 (3), 340-345, 2019
382019
Prokaryotic substrate-binding proteins as targets for antimicrobial therapies
R M Counago, C A McDevitt, M P Ween, B Kobe
Current Drug Targets 13 (11), 1400-1410, 2012
382012
Experimental evolution of adenylate kinase reveals contrasting strategies toward protein thermostability
C Miller, M Davlieva, C Wilson, KI White, R Couñago, G Wu, JC Myers, ...
Biophysical journal 99 (3), 887-896, 2010
342010
Biochemical and structural characterization of alanine racemase from Bacillus anthracis (Ames)
RM Couñago, M Davlieva, U Strych, RE Hill, KL Krause
BMC structural biology 9, 1-15, 2009
342009
Novel bacterial MerR-like regulators: Their role in the response to carbonyl and nitrosative stress
AG McEwan, KY Djoko, NH Chen, RLM Couñago, SP Kidd, AJ Potter, ...
Advances in microbial physiology 58, 1-22, 2011
332011
Mitochondrial uncoupling protein-dependent signaling in plant bioenergetics and stress response
P Barreto, RM Counago, P Arruda
Mitochondrion 53, 109-120, 2020
302020
Structural characterization of human Vaccinia-Related Kinases (VRK) bound to small-molecule inhibitors identifies different P-loop conformations
RM Couñago, CK Allerston, P Savitsky, H Azevedo, PH Godoi, CI Wells, ...
Scientific reports 7 (1), 7501, 2017
292017
Structures of Orf virus chemokine binding protein in complex with host chemokines reveal clues to broad binding specificity
RM Couñago, KM Knapp, Y Nakatani, SB Fleming, M Corbett, LM Wise, ...
Structure 23 (7), 1199-1213, 2015
292015
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