Thioredoxin nuclear translocation and interaction with redox factor-1 activates the activator protein-1 transcription factor in response to ionizing radiation SJ Wei, A Botero, K Hirota, CM Bradbury, S Markovina, A Laszlo, DR Spitz, ... Cancer research 60 (23), 6688-6695, 2000 | 246 | 2000 |
Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach D Gius, H Cui, CM Bradbury, J Cook, DDK Smart, S Zhao, L Young, ... Cancer cell 6 (4), 361-371, 2004 | 221 | 2004 |
Geldanamycin and 17-allylamino-17-demethoxygeldanamycin potentiate the in vitro and in vivo radiation response of cervical tumor cells via the heat shock protein 90-mediated … KS Bisht, CM Bradbury, D Mattson, A Kaushal, A Sowers, S Markovina, ... Cancer research 63 (24), 8984-8995, 2003 | 219 | 2003 |
Epigenetic silencing of novel tumor suppressors in malignant melanoma V Muthusamy, S Duraisamy, CM Bradbury, C Hobbs, DP Curley, B Nelson, ... Cancer research 66 (23), 11187-11193, 2006 | 207 | 2006 |
2-Deoxy-D-glucose-induced cytotoxicity and radiosensitization in tumor cells is mediated via disruptions in thiol metabolism X Lin, F Zhang, CM Bradbury, A Kaushal, L Li, DR Spitz, RL Aft, D Gius Cancer research 63 (12), 3413-3417, 2003 | 194 | 2003 |
Thioredoxin reductase regulates AP-1 activity as well as thioredoxin nuclear localization via active cysteines in response to ionizing radiation S Karimpour, J Lou, LL Lin, LM Rene, L Lagunas, X Ma, S Karra, ... Oncogene 21 (41), 6317-6327, 2002 | 157 | 2002 |
Thioredoxin reductase as a potential molecular target for anticancer agents that induce oxidative stress DDK Smart, KL Ortiz, D Mattson, CM Bradbury, KS Bisht, LK Sieck, ... Cancer research 64 (18), 6716-6724, 2004 | 151 | 2004 |
Radiosensitizing and anti-proliferative effects of resveratrol in two human cervical tumor cell lines I Zoberi, CM Bradbury, HA Curry, KS Bisht, PC Goswami, JLR Roti, D Gius Cancer letters 175 (2), 165-173, 2002 | 144 | 2002 |
Heat shock inhibits radiation-induced activation of NF-κB via inhibition of I-κB kinase HA Curry, RA Clemens, S Shah, CM Bradbury, A Botero, P Goswami, ... Journal of Biological Chemistry 274 (33), 23061-23067, 1999 | 115 | 1999 |
Profiling microdissected epithelium and stroma to model genomic signatures for cervical carcinogenesis accommodating for covariates D Gius, MC Funk, EY Chuang, S Feng, PC Huettner, L Nguyen, ... Cancer research 67 (15), 7113-7123, 2007 | 114 | 2007 |
Indomethacin-induced radiosensitization and inhibition of ionizing radiation-induced NF-κB activation in HeLa cells occur via a mechanism involving p38 MAP kinase CM Bradbury, S Markovina, SJ Wei, LM Rene, I Zoberi, N Horikoshi, ... Cancer research 61 (20), 7689-7696, 2001 | 88 | 2001 |
DNA methyltransferase 1 and 3B activate BAG-1 expression via recruitment of CTCFL/BORIS and modulation of promoter histone methylation L Sun, L Huang, P Nguyen, KS Bisht, G Bar-Sela, AS Ho, CM Bradbury, ... Cancer research 68 (8), 2726-2735, 2008 | 64 | 2008 |
DNMT1 as a molecular target in a multimodality-resistant phenotype in tumor cells MV Mishra, KS Bisht, L Sun, K Muldoon-Jacobs, R Awwad, A Kaushal, ... Molecular Cancer Research 6 (2), 243-249, 2008 | 54 | 2008 |
Distinct effects of ionizing radiation on in vivo murine kidney and brain normal tissue gene expression W Zhao, EY Chuang, M Mishra, R Awwad, K Bisht, L Sun, P Nguyen, ... Clinical cancer research 12 (12), 3823-3830, 2006 | 37 | 2006 |
Heat shock and the activation of AP-1 and inhibition of NF-κB DNA-binding activity: possible role of intracellular redox status D Mattson, CM Bradbury, KS Bisht, HA Curry, DR Spitz, D Gius International journal of hyperthermia 20 (2), 224-233, 2004 | 37 | 2004 |
The epigenome as a molecular marker and target: Implications for cancer D Gius, CM Bradbury, L Sun, RT Awwad, L Huang, DDK Smart, KS Bisht, ... Cancer: Interdisciplinary International Journal of the American Cancer …, 2005 | 30 | 2005 |
Indomethacin and ibuprofen induce Hsc70 nuclear localization and activation of the heat shock response in HeLa cells L Lagunas, CM Bradbury, A Laszlo, CR Hunt, D Gius Biochemical and biophysical research communications 313 (4), 863-870, 2004 | 27 | 2004 |
Increased activator protein 1 activity as well as resistance to heat-induced radiosensitization, hydrogen peroxide, and cisplatin are inhibited by indomethacin in oxidative … CM Bradbury, JE Locke, SJ Wei, LM Rene, S Karimpour, C Hunt, DR Spitz, ... Cancer research 61 (8), 3486-3492, 2001 | 24 | 2001 |
Indomethacin lowers the threshold thermal exposure for hyperthermic radiosensitization and heat-shock inhibition of ionizing radiation-induced activation of NF-κB JE Locke, CM Bradbury, SJ Wei, S Shah, LM Rene, RA Clemens, JR Roti, ... International journal of radiation biology 78 (6), 493-502, 2002 | 19 | 2002 |
Thermal stress and the disruption of redox-sensitive signalling and transcription factor activation: possible role in radiosensitization D Gius, D Mattson, CM Bradbury, DK Smart, DR Spitz International journal of hyperthermia 20 (2), 213-223, 2004 | 18 | 2004 |