The effect of glycosaminoglycans (GAGs) on amyloid aggregation and toxicity C Iannuzzi, G Irace, I Sirangelo Molecules 20 (2), 2510-2528, 2015 | 133 | 2015 |
Differential effects of glycation on protein aggregation and amyloid formation C Iannuzzi, G Irace, I Sirangelo Frontiers in molecular biosciences 1, 9, 2014 | 120 | 2014 |
Fibrillogenesis and cytotoxic activity of the amyloid-forming apomyoglobin mutant W7FW14F I Sirangelo, C Malmo, C Iannuzzi, A Mezzogiorno, MR Bianco, M Papa, ... Journal of Biological Chemistry 279 (13), 13183-13189, 2004 | 96 | 2004 |
Insights into insulin fibril assembly at physiological and acidic pH and related amyloid intrinsic fluorescence C Iannuzzi, M Borriello, M Portaccio, G Irace, I Sirangelo International journal of molecular sciences 18 (12), 2551, 2017 | 72 | 2017 |
Apomyoglobin folding intermediates characterized by the hydrophobic fluorescent probe 8-anilino-1-naphthalene sulfonate (ANS) I Sirangelo, E Bismuto, S Tavassi, G Irace Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 1998 | 67 | 1998 |
The role of metal binding in the amyotrophic lateral sclerosis-related aggregation of copper-zinc superoxide dismutase I Sirangelo, C Iannuzzi Molecules 22 (9), 1429, 2017 | 65 | 2017 |
Heparin induces harmless fibril formation in amyloidogenic W7FW14F apomyoglobin and amyloid aggregation in wild-type protein in vitro S Vilasi, R Sarcina, R Maritato, A De Simone, G Irace, I Sirangelo PloS one 6 (7), e22076, 2011 | 65 | 2011 |
Stachydrine ameliorates high‐glucose induced endothelial cell senescence and SIRT 1 downregulation L Servillo, N D'Onofrio, L Longobardi, I Sirangelo, A Giovane, D Cautela, ... Journal of cellular biochemistry 114 (11), 2522-2530, 2013 | 62 | 2013 |
Effect of trehalose on W7FW14F apomyoglobin and insulin fibrillization: new insight into inhibition activity S Vilasi, C Iannuzzi, M Portaccio, G Irace, I Sirangelo Biochemistry 47 (6), 1789-1796, 2008 | 57 | 2008 |
Tryptophanyl substitutions in apomyoglobin determine protein aggregation and amyloid-like fibril formation at physiological pH I Sirangelo, C Malmo, M Casillo, A Mezzogiorno, M Papa, G Irace Journal of Biological Chemistry 277 (48), 45887-45891, 2002 | 53 | 2002 |
Misfolding and amyloid aggregation of apomyoglobin C Iannuzzi, R Maritato, G Irace, I Sirangelo International journal of molecular sciences 14 (7), 14287-14300, 2013 | 51 | 2013 |
Vanillin affects amyloid aggregation and non-enzymatic glycation in human insulin C Iannuzzi, M Borriello, G Irace, M Cammarota, A Di Maro, I Sirangelo Scientific Reports 7 (1), 15086, 2017 | 50 | 2017 |
Time-resolved small-angle X-ray scattering study of the early formation of amyloid protofibrils on a apomyoglobin mutant MG Ortore, F Spinozzi, S Vilasi, I Sirangelo, G Irace, A Shukla, ... Biophysical Journal 100 (3), 532a, 2011 | 50 | 2011 |
The effect of tryptophanyl substitution on folding and structure of myoglobin I Sirangelo, S Tavassi, PL Martelli, R Casadio, G Irace European Journal of Biochemistry 267 (13), 3937-3945, 2000 | 44 | 2000 |
D-ribose-glycation of insulin prevents amyloid aggregation and produces cytotoxic adducts C Iannuzzi, M Borriello, V Carafa, L Altucci, M Vitiello, ML Balestrieri, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1862 (1), 93-104, 2016 | 42 | 2016 |
Understanding the role of protein glycation in the amyloid aggregation process I Sirangelo, C Iannuzzi International Journal of Molecular Sciences 22 (12), 6609, 2021 | 41 | 2021 |
Pressure-induced perturbation of apomyoglobin structure: Fluorescence studies on native and acidic compact forms E Bismuto, I Sirangelo, G Irace, E Gratton Biochemistry 35 (4), 1173-1178, 1996 | 41 | 1996 |
Tetracycline inhibits W7FW14F apomyoglobin fibril extension and keeps the amyloid protein in a prefibrillar, highly cytotoxic state C Malmo, S Vilasi, C Iannuzzi, S Tacchi, C Cametti, G Irace, I Sirangelo The FASEB journal 20 (2), 346-347, 2006 | 39 | 2006 |
Glycation accelerates fibrillization of the amyloidogenic W7FW14F apomyoglobin C Iannuzzi, R Maritato, G Irace, I Sirangelo PLoS One 8 (12), e80768, 2013 | 37 | 2013 |
Hexafluoroisopropanol and acid destabilized forms of apomyoglobin exhibit structural differences I Sirangelo, F Dal Piaz, C Malmo, M Casillo, L Birolo, P Pucci, G Marino, ... Biochemistry 42 (2), 312-319, 2003 | 36 | 2003 |