Christoph Thiemermann
Christoph Thiemermann
Centre Lead for Translational Medicine & Therapeutics, Queen Mary University of London
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Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase
JA Mitchell, P Akarasereenont, C Thiemermann, RJ Flower, JR Vane
Proceedings of the National Academy of Sciences 90 (24), 11693-11697, 1993
Inhibition of nitric oxide synthesis reduces the hypotension induced by bacterial lipopolysaccharides in the rat in vivo
C Thiemermann, J Vane
European journal of pharmacology 182 (3), 591-595, 1990
Beneficial effects and improved survival in rodent models of septic shock with S-methylisothiourea sulfate, a potent and selective inhibitor of inducible nitric oxide synthase
C Szabo, GJ Southan, C Thiemermann
Proceedings of the National Academy of Sciences 91 (26), 12472-12476, 1994
Nitric oxide‐mediated hyporeactivity to noradrenaline precedes the induction of nitric oxide synthase in endotoxin shock
C Szabo, JA Mitchell, C Thiemermann, JR Vane
British journal of pharmacology 108 (3), 786-792, 1993
Erythropoietin protects the kidney against the injury and dysfunction caused by ischemia-reperfusion
EJ Sharples, N Patel, P Brown, K Stewart, H Mota-Philipe, M Sheaff, ...
Journal of the American Society of Nephrology 15 (8), 2115-2124, 2004
Ligands of the peroxisome proliferator-activated receptors (PPAR-γ and PPAR-α) reduce myocardial infarct size
NS Wayman, Y Hattori, MC McDonald, H MOTA-FILIPE, S CUZZOCREA, ...
The FASEB Journal 16 (9), 1027-1040, 2002
Vascular hyporeactivity to vasoconstrictor agents and hemodynamic decompensation in hemorrhagic shock is mediated by nitric oxide
C Thiemermann, C Szabo, JA Mitchell, JR Vane
Proceedings of the National Academy of Sciences 90 (1), 267-271, 1993
The cell wall components peptidoglycan and lipoteichoic acid from Staphylococcus aureus act in synergy to cause shock and multiple organ failure
SJ De Kimpe, M Kengatharan, C Thiemermann, JR Vane
Proceedings of the National Academy of Sciences 92 (22), 10359-10363, 1995
Inhibition of the activity of poly (ADP ribose) synthetase reduces ischemia–reperfusion injury in the heart and skeletal muscle
C Thiemermann, J Bowes, FP Myint, JR Vane
Proceedings of the National Academy of Sciences 94 (2), 679-683, 1997
Nitric oxide and septic shock
C Thiemermann
General Pharmacology: The Vascular System 29 (2), 159-166, 1997
Tempol, a membrane-permeable radical scavenger, reduces oxidant stress-mediated renal dysfunction and injury in the rat
PK Chatterjee, S Cuzzocrea, PAJ Brown, K Zacharowski, KN Stewart, ...
Kidney international 58 (2), 658-673, 2000
Isothioureas: potent inhibitors of nitric oxide synthases with variable isoform selectivity
GJ Southan, C Szabó, C Thiemermann
British journal of pharmacology 114 (2), 510-516, 1995
Nonerythropoietic, tissue-protective peptides derived from the tertiary structure of erythropoietin
M Brines, NSA Patel, P Villa, C Brines, T Mennini, M De Paola, ...
Proceedings of the National Academy of Sciences 105 (31), 10925-10930, 2008
Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-γ, reduces acute inflammation
S Cuzzocrea, B Pisano, L Dugo, A Ianaro, P Maffia, NSA Patel, R Di Paola, ...
European journal of pharmacology 483 (1), 79-93, 2004
Inhibition of inducible nitric oxide synthase reduces renal ischemia/reperfusion injury
PK Chatterjee, NSA Patel, EO Kvale, S Cuzzocrea, PAJ Brown, ...
Kidney international 61 (3), 862-871, 2002
On the selectivity of superoxide dismutase mimetics and its importance in pharmacological studies
C Muscoli, S Cuzzocrea, DP Riley, JL Zweier, C Thiemermann, ZQ Wang, ...
British journal of pharmacology 140 (3), 445-460, 2003
Mechanism of gram-positive shock: identification of peptidoglycan and lipoteichoic acid moieties essential in the induction of nitric oxide synthase, shock, and multiple organ …
KM Kengatharan, S De Kimpe, C Robson, SJ Foster, C Thiemermann
Journal of Experimental Medicine 188 (2), 305-315, 1998
Beneficial effects of PPAR-γ ligands in ischemia–reperfusion injury, inflammation and shock
M Abdelrahman, A Sivarajah, C Thiemermann
Cardiovascular research 65 (4), 772-781, 2005
Pretreatment with EPO reduces the injury and dysfunction caused by ischemia/reperfusion in the mouse kidney in vivo
NSA Patel, EJ Sharples, S Cuzzocrea, PK Chatterjee, D Britti, MM Yaqoob, ...
Kidney international 66 (3), 983-989, 2004
Anti-apoptotic and anti-inflammatory effects of hydrogen sulfide in a rat model of regional myocardial I/R
A Sivarajah, M Collino, M Yasin, E Benetti, M Gallicchio, E Mazzon, ...
Shock 31 (3), 267-274, 2009
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