| On-demand manufacturing of clinical-quality biopharmaceuticals LE Crowell, AE Lu, KR Love, A Stockdale, SM Timmick, D Wu, Y Wang, ... Nature biotechnology 36 (10), 988-995, 2018 | 102 | 2018 |
| An impurity characterization based approach for the rapid development of integrated downstream purification processes SM Timmick, N Vecchiarello, C Goodwine, LE Crowell, KR Love, JC Love, ... Biotechnology and Bioengineering 115 (8), 2048-2060, 2018 | 28 | 2018 |
| A combined screening and in silico strategy for the rapid design of integrated downstream processes for process and product‐related impurity removal N Vecchiarello, SM Timmick, C Goodwine, LE Crowell, KR Love, JC Love, ... Biotechnology and Bioengineering 116 (9), 2178-2190, 2019 | 14 | 2019 |
| Quantifying orthogonality and separability: A method for optimizing resin selection and design CL Bilodeau, NA Vecchiarello, S Altern, SM Cramer Journal of Chromatography A 1628, 461429, 2020 | 7 | 2020 |
| Design of peptide ligands for affinity purification of human growth hormone D Chandra, S Timmick, C Goodwine, N Vecchiarello, DG Shastry, ... Journal of Chemical Technology & Biotechnology 94 (7), 2345-2354, 2019 | 7 | 2019 |
| A framework for calculating orthogonal selectivities in multimodal systems directly from cell culture fluid N Vecchiarello, SM Timmick, S Cramer Biotechnology and Bioengineering 119 (1), 299-314, 2022 | 2 | 2022 |
| Systems and methods for manufacturing biologically-produced products JC Love, KR Love, L Crowell, A Stockdale, RD Braatz, AE Lu, S Cramer, ... US Patent App. 16/499,780, 2020 | 2 | 2020 |
| In Silico Design of Integrated Chromatographic Purification Processes for Therapeutic Proteins NA Vecchiarello Rensselaer Polytechnic Institute, 2019 | 2 | 2019 |
| Continuous Drug Product N Vecchiarello 2021 AIChE Annual Meeting, 2021 | 1 | 2021 |
| Predictive Scale-Up/Scale-Down for Pharmaceuticals and Biopharmaceuticals# 2 O Manjrekar, M Eccles, N Vecchiarello 2023 AIChE Annual Meeting, 2023 | | 2023 |
| Systems and methods for manufacturing biologically-produced products JC Love, KR Love, L Crowell, A Stockdale, RD Braatz, AE Lu, S Cramer, ... US Patent App. 17/690,876, 2023 | | 2023 |
| Predictive Scale-Up/Scale-Down for Production of Pharmaceuticals and Biopharmaceuticals II O Manjrekar, N Vecchiarello, M Eccles 2022 AIChE Annual Meeting, 2022 | | 2022 |
| Product agnostic tool for quantifying separability and orthogonality for individual and sequential separation processes SM Cramer, NA Vecchiarello, CL Bilodeau US Patent App. 17/605,645, 2022 | | 2022 |
| Continuous Drug Substance–Integrated Processes-Session 2 N Vecchiarello 2021 AIChE Annual Meeting, 2021 | | 2021 |
| High Throughput Process Development for CEX Chromatography N Vecchiarello, P Shah, N Jacob, G Bolton 2020 Virtual AIChE Annual Meeting, 2020 | | 2020 |
| Systems and methods for using behavior data of impurities and target proteins to design downstream processes JC Love, KR Love, S Cramer, S Timmick, N Vecchiarello, C Goodwine, ... US Patent App. 16/499,776, 2020 | | 2020 |
| In-silico aided strategy for efficient and rapid design of integrated purification processes N Vecchiarello, S Cramer ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019 | | 2019 |
| Rapid, end-to-end manufacturing of biologics enabled by a universal starter process for purification of proteins produced in Pichia pastoris L Crowell, N Vecchiarello, K Love, S Cramer, C Love ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019 | | 2019 |
| In silico design of integrated downstream processes for non-mAb biologics produced in complex expression systems N Vecchiarello, C Goodwine, S Cramer ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 255, 2018 | | 2018 |
| Integrated purification process development for the single-domain variable fragment of camelid antibodies C Goodwine, N Vecchiarello, K Love, J Love, S Cramer ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 255, 2018 | | 2018 |
