|T-helper type 2–driven inflammation defines major subphenotypes of asthma|
PG Woodruff, B Modrek, DF Choy, G Jia, AR Abbas, A Ellwanger, ...
American journal of respiratory and critical care medicine 180 (5), 388-395, 2009
|Azithromycin for prevention of exacerbations of COPD|
RK Albert, J Connett, WC Bailey, R Casaburi, JAD Cooper Jr, GJ Criner, ...
New England Journal of Medicine 365 (8), 689-698, 2011
|Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids|
PG Woodruff, HA Boushey, GM Dolganov, CS Barker, YH Yang, ...
Proceedings of the National Academy of Sciences 104 (40), 15858-15863, 2007
|Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients|
G Jia, RW Erickson, DF Choy, S Mosesova, LC Wu, OD Solberg, ...
Journal of Allergy and Clinical Immunology 130 (3), 647-654. e10, 2012
|Muc5b is required for airway defence|
MG Roy, A Livraghi-Butrico, AA Fletcher, MM McElwee, SE Evans, ...
Nature 505 (7483), 412-416, 2014
|Hyperplasia of smooth muscle in mild to moderate asthma without changes in cell size or gene expression|
PG Woodruff, GM Dolganov, RE Ferrando, S Donnelly, SR Hays, ...
American journal of respiratory and critical care medicine 169 (9), 1001-1006, 2004
|Clinical significance of symptoms in smokers with preserved pulmonary function|
PG Woodruff, RG Barr, E Bleecker, SA Christenson, D Couper, JL Curtis, ...
New England Journal of Medicine 374 (19), 1811-1821, 2016
|Roles of epithelial cell-derived periostin in TGF-β activation, collagen production, and collagen gel elasticity in asthma|
SS Sidhu, S Yuan, AL Innes, S Kerr, PG Woodruff, L Hou, SJ Muller, ...
Proceedings of the national academy of sciences 107 (32), 14170-14175, 2010
|Simvastatin for the prevention of exacerbations in moderate-to-severe COPD|
GJ Criner, JE Connett, SD Aaron, RK Albert, WC Bailey, R Casaburi, ...
New England Journal of Medicine 370 (23), 2201-2210, 2014
|Dissecting asthma using focused transgenic modeling and functional genomics|
DA Kuperman, CC Lewis, PG Woodruff, MW Rodriguez, YH Yang, ...
Journal of Allergy and Clinical Immunology 116 (2), 305-311, 2005
|Relationship between airway inflammation, hyperresponsiveness, and obstruction in asthma|
PG Woodruff, R Khashayar, SC Lazarus, S Janson, P Avila, HA Boushey, ...
Journal of Allergy and Clinical Immunology 108 (5), 753-758, 2001
|Measures of gene expression in sputum cells can identify TH2-high and TH2-low subtypes of asthma|
MC Peters, ZK Mekonnen, S Yuan, NR Bhakta, PG Woodruff, JV Fahy
Journal of Allergy and Clinical Immunology 133 (2), 388-394. e5, 2014
|Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction|
F Huang, H Zhang, M Wu, H Yang, M Kudo, CJ Peters, PG Woodruff, ...
Proceedings of the National Academy of Sciences 109 (40), 16354-16359, 2012
|Cigarette smoking among asthmatic adults presenting to 64 emergency departments|
RA Silverman, ED Boudreaux, PG Woodruff, S Clark, CA Camargo Jr, ...
Chest 123 (5), 1472-1479, 2003
|Asthma–COPD overlap. Clinical relevance of genomic signatures of type 2 inflammation in chronic obstructive pulmonary disease|
SA Christenson, K Steiling, M van den Berge, K Hijazi, PS Hiemstra, ...
American journal of respiratory and critical care medicine 191 (7), 758-766, 2015
|Altered microRNA profiles in bronchoalveolar lavage fluid exosomes in asthmatic patients|
B Levänen, NR Bhakta, PT Paredes, R Barbeau, S Hiltbrunner, JL Pollack, ...
Journal of Allergy and Clinical Immunology 131 (3), 894-903. e8, 2013
|Human asthma phenotypes: from the clinic, to cytokines, and back again|
NR Bhakta, PG Woodruff
Immunological reviews 242 (1), 220-232, 2011
|Design of the subpopulations and intermediate outcomes in COPD study (SPIROMICS)|
D Couper, LM LaVange, ML Han, RG Barr, E Bleecker, EA Hoffman, ...
Thorax 69 (5), 492-495, 2014
|Accumulation of intraepithelial mast cells with a unique protease phenotype in TH2-high asthma|
RH Dougherty, SS Sidhu, K Raman, M Solon, OD Solberg, GH Caughey, ...
Journal of Allergy and Clinical Immunology 125 (5), 1046-1053. e8, 2010
|A distinctive alveolar macrophage activation state induced by cigarette smoking|
PG Woodruff, LL Koth, YH Yang, MW Rodriguez, S Favoreto, ...
American journal of respiratory and critical care medicine 172 (11), 1383-1392, 2005