Multi-column displacement chromatography for separation of charge variants of monoclonal antibodies O Khanal, V Kumar, K Westerberg, F Schlegel, AM Lenhoff Journal of Chromatography A 1586, 40-51, 2019 | 54 | 2019 |
Contributions of the wall boundary layer to the formation of the counter-rotating vortex pair in transverse jets F Schlegel, D Wee, YM Marzouk, AF Ghoniem Journal of fluid mechanics 676, 461-490, 2011 | 36 | 2011 |
Robust mechanistic modeling of protein ion-exchange chromatography V Kumar, S Leweke, W Heymann, E von Lieres, F Schlegel, K Westerberg, ... Journal of Chromatography A 1660, 462669, 2021 | 30 | 2021 |
Toward in silico CMC: An industrial collaborative approach to model‐based process development D Roush, D Asthagiri, DK Babi, S Benner, C Bilodeau, G Carta, P Ernst, ... Biotechnology and bioengineering 117 (12), 3986-4000, 2020 | 30 | 2020 |
Estimating and leveraging protein diffusion on ion-exchange resin surfaces O Khanal, V Kumar, F Schlegel, AM Lenhoff Proceedings of the National Academy of Sciences 117 (13), 7004-7010, 2020 | 21 | 2020 |
Y.. MM Arzouk and AF Ghoniem," F Schlegel, D Wee Contributions of the wall boundary layer to the formation of the counter …, 2011 | 21 | 2011 |
Simulation of a high Reynolds number reactive transverse jet and the formation of a triple flame F Schlegel, AF Ghoniem Combustion and Flame 161 (4), 971–986, 2013 | 19 | 2013 |
A fast 3D particle method for the simulation of buoyant flow F Schlegel, D Wee, AF Ghoniem Journal of Computational Physics 227 (21), 9063-9090, 2008 | 17 | 2008 |
Advanced score system and automated search strategies for parameter estimation in mechanistic chromatography modeling W Heymann, J Glaser, F Schlegel, W Johnson, P Rolandi, E von Lieres Journal of Chromatography A 1661, 462693, 2022 | 14 | 2022 |
Convergence characteristics and computational cost of two algebraic kernels in vortex methods with a tree-code algorithm D Wee, YM Marzouk, F Schlegel, AF Ghoniem SIAM Journal on Scientific Computing 31 (4), 2510-2527, 2009 | 7 | 2009 |
Advanced error modeling and Bayesian uncertainty quantification in mechanistic liquid chromatography modeling W Heymann, J Glaser, F Schlegel, W Johnson, P Rolandi, E Von Lieres Journal of Chromatography A 1708, 464329, 2023 | 2 | 2023 |
COSMIC-dFBA: A novel multi-scale hybrid framework for bioprocess modeling S Gopalakrishnan, W Johnson, MA Valderrama-Gomez, E Icten, J Tat, ... Metabolic Engineering, 2024 | 1 | 2024 |
Multi-omic characterization of antibody-producing CHO cell lines elucidates metabolic reprogramming and nutrient uptake bottlenecks S Gopalakrishnan, W Johnson, MAV Gomez, E Icten, J Tat, F Lay, J Diep, ... bioRxiv, 2023.09. 13.557626, 2023 | 1 | 2023 |
Predicting Shelf Life Stability of Lyophilized Drug Products RC Kelly, M Chaves, MA Caporini, F Schlegel US Patent App. 18/025,311, 2024 | | 2024 |
CFD Simulation of Impulse Mixers I Mirzaee, J Wutz, J Thomas, M Ahmadi, SJ Kang, S Golshan, F Schlegel, ... 2023 AIChE Annual Meeting, 2023 | | 2023 |
Monitoring Vial Conditions During a Lyophilization Process CJ Garvin, F Schlegel, G Scalzo, C Bambury, D Bac, C Ruitberg US Patent App. 17/924,925, 2023 | | 2023 |
An Industrial in silico Modeling Platform for Reliable, Efficient, and Agile Process & Product Development F Schlegel, PA Rolandi, I Mirzaee, M Maritato, S Seifi, ... 2022 AIChE Annual Meeting, 2022 | | 2022 |
Multi-Scale Modeling of a CHO Production Process Using Integrated Machine Learning Models and Genome-Scale Metabolic Models S Gopalakrishnan, J Tat, MA Valderrama-Gomez, F Schlegel, PA Rolandi, ... 2022 AIChE Annual Meeting, 2022 | | 2022 |
Predicting Antibody Titer Using Multi-Scale Dynamic Flux Balance Analysis Bioreactor Models S Gopalakrishnan, J Tat, MA Valderrama-Gomez, F Schlegel, W Johnson, ... 2022 AIChE Annual Meeting, 2022 | | 2022 |
In silico Modeling of Roller Compaction Processes for Scale-up and Tech Transfer: One Step Closer to Digital Twins EI Gencer, D Shen, D Nguyen, D Perez-Aguilar, MH Rad, S Gour, ... 2022 AIChE Annual Meeting, 2022 | | 2022 |