Transcriptional landscape and clinical utility of enhancer RNAs for eRNA-targeted therapy in cancer Z Zhang, JH Lee, H Ruan, Y Ye, J Krakowiak, Q Hu, Y Xiang, J Gong, ... Nature communications 10 (1), 4562, 2019 | 188 | 2019 |
Enhancer RNA m6A methylation facilitates transcriptional condensate formation and gene activation JH Lee, R Wang, F Xiong, J Krakowiak, Z Liao, PT Nguyen, ... Molecular cell 81 (16), 3368-3385. e9, 2021 | 152 | 2021 |
A dual role for UVRAG in maintaining chromosomal stability independent of autophagy Z Zhao, S Oh, D Li, D Ni, SD Pirooz, JH Lee, S Yang, JY Lee, I Ghozalli, ... Developmental cell 22 (5), 1001-1016, 2012 | 122 | 2012 |
PtdIns (3) P-bound UVRAG coordinates Golgi–ER retrograde and Atg9 transport by differential interactions with the ER tether and the beclin 1 complex S He, D Ni, B Ma, JH Lee, T Zhang, I Ghozalli, SD Pirooz, Z Zhao, ... Nature cell biology 15 (10), 1206-1219, 2013 | 105 | 2013 |
Cell-surface Receptor for Complement Component C1q (gC1qR) Is a Key Regulator for Lamellipodia Formation and Cancer Metastasis*♦ KB Kim, JS Yi, N Nguyen, JH Lee, YC Kwon, BY Ahn, H Cho, YK Kim, ... Journal of Biological Chemistry 286 (26), 23093-23101, 2011 | 87 | 2011 |
Truncating mutation in the autophagy gene UVRAG confers oncogenic properties and chemosensitivity in colorectal cancers S He, Z Zhao, Y Yang, D O'connell, X Zhang, S Oh, B Ma, JH Lee, ... Nature communications 6 (1), 7839, 2015 | 83 | 2015 |
Enhancer release and retargeting activates disease-susceptibility genes S Oh, J Shao, J Mitra, F Xiong, M D’Antonio, R Wang, I Garcia-Bassets, ... Nature 595 (7869), 735-740, 2021 | 82 | 2021 |
Enhancer RNAs in cancer: regulation, mechanisms and therapeutic potential JH Lee, F Xiong, W Li RNA biology 17 (11), 1550-1559, 2020 | 78 | 2020 |
RNA m6A modification orchestrates a LINE-1–host interaction that facilitates retrotransposition and contributes to long gene vulnerability F Xiong, R Wang, JH Lee, S Li, SF Chen, Z Liao, LA Hasani, PT Nguyen, ... Cell Research 31 (8), 861-885, 2021 | 53 | 2021 |
SARS-CoV-2 restructures host chromatin architecture R Wang, JH Lee, J Kim, F Xiong, LA Hasani, Y Shi, EN Simpson, X Zhu, ... Nature microbiology 8 (4), 679-694, 2023 | 49 | 2023 |
The SINEB1 element in the long non-coding RNA Malat1 is necessary for TDP-43 proteostasis TM Nguyen, EB Kabotyanski, LC Reineke, J Shao, F Xiong, JH Lee, ... Nucleic acids research 48 (5), 2621-2642, 2020 | 47 | 2020 |
Lipid raft proteome reveals that oxidative phosphorylation system is associated with the plasma membrane BW Kim, CS Lee, JS Yi, JH Lee, JW Lee, HJ Choo, SY Jung, MS Kim, ... Expert review of proteomics 7 (6), 849-866, 2010 | 28 | 2010 |
Mitochondrial oxidative phosphorylation system is recruited to detergent‐resistant lipid rafts during myogenesis BW Kim, JW Lee, HJ Choo, CS Lee, SY Jung, JS Yi, YM Ham, JH Lee, ... Proteomics 10 (13), 2498-2515, 2010 | 27 | 2010 |
TPL2 is an oncogenic driver in keratocanthoma and squamous cell carcinoma JH Lee, JH Lee, SH Lee, SI Do, SD Cho, O Forslund, KS Inn, JS Lee, ... Cancer Research 76 (22), 6712-6722, 2016 | 26 | 2016 |
NANOG prion-like assembly mediates DNA bridging to facilitate chromatin reorganization and activation of pluripotency KJ Choi, MD Quan, C Qi, JH Lee, PS Tsoi, M Zahabiyon, A Bajic, L Hu, ... Nature cell biology 24 (5), 737-747, 2022 | 19 | 2022 |
Acute depletion of human core nucleoporin reveals direct roles in transcription control but dispensability for 3D genome organization X Zhu, C Qi, R Wang, JH Lee, J Shao, L Bei, F Xiong, PT Nguyen, G Li, ... Cell reports 41 (5), 2022 | 10 | 2022 |
Measurement of γHV68 infection in mice SD Pirooz, JH Lee, Z Zhao, D Ni, S Oh, C Liang JoVE (Journal of Visualized Experiments), e3472, 2011 | 2 | 2011 |
Enforced Activation of Enhancer RNAs In Situ through the dCas9 Synergistic Activation Mediator System Z Liao, JH Lee, J Krakowiak, R Wang, W Li JoVE (Journal of Visualized Experiments), e61460, 2020 | | 2020 |