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Anne Le
Anne Le
Gigantest, Inc.
Email verificata su gigantest.com - Home page
Titolo
Citata da
Citata da
Anno
Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
A Le, CR Cooper, AM Gouw, R Dinavahi, A Maitra, LM Deck, RE Royer, ...
Proceedings of the National Academy of Sciences 107 (5), 2037-2042, 2010
14832010
Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells
A Le, AN Lane, M Hamaker, S Bose, A Gouw, J Barbi, T Tsukamoto, ...
Cell metabolism 15 (1), 110-121, 2012
11562012
MYC-induced cancer cell energy metabolism and therapeutic opportunities
CV Dang, A Le, P Gao
Clinical Cancer Research 15 (21), 6479-6483, 2009
10032009
Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC
W Liu, A Le, C Hancock, AN Lane, CV Dang, TWM Fan, JM Phang
Proceedings of the National Academy of Sciences 109 (23), 8983-8988, 2012
4962012
Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis
Y Xiang, ZE Stine, J Xia, Y Lu, RS O’Connor, BJ Altman, AL Hsieh, ...
The Journal of clinical investigation 125 (6), 2293-2306, 2015
4422015
Quantitative determinants of aerobic glycolysis identify flux through the enzyme GAPDH as a limiting step
AA Shestov, X Liu, Z Ser, AA Cluntun, YP Hung, L Huang, D Kim, A Le, ...
elife 3, e03342, 2014
3162014
Designing a broad-spectrum integrative approach for cancer prevention and treatment
KI Block, C Gyllenhaal, L Lowe, A Amedei, ARMR Amin, A Amin, ...
Seminars in cancer biology 35, S276-S304, 2015
3002015
Dysregulated metabolism contributes to oncogenesis
MD Hirschey, RJ DeBerardinis, AME Diehl, JE Drew, C Frezza, MF Green, ...
Seminars in cancer biology 35, S129-S150, 2015
3002015
Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer
A Elgogary, Q Xu, B Poore, J Alt, SC Zimmermann, L Zhao, J Fu, B Chen, ...
Proceedings of the National Academy of Sciences 113 (36), E5328-E5336, 2016
2142016
Therapeutic targeting of cancer cell metabolism
CV Dang, M Hamaker, P Sun, A Le, P Gao
Journal of molecular medicine 89 (3), 205-212, 2011
2122011
Mitochondrial copper depletion suppresses triple-negative breast cancer in mice
L Cui, AM Gouw, EL LaGory, S Guo, N Attarwala, Y Tang, J Qi, YS Chen, ...
Nature biotechnology 39 (3), 357-367, 2021
1772021
Glucose metabolism in cancer
S Bose, A Le
The Heterogeneity of Cancer Metabolism, 3-12, 2018
1652018
Therapeutic targeting of the Warburg effect in pancreatic cancer relies on an absence of p53 function
NV Rajeshkumar, P Dutta, S Yabuuchi, RF De Wilde, GV Martinez, A Le, ...
Cancer research 75 (16), 3355-3364, 2015
1622015
Glutamine metabolism in cancer
T Li, A Le
The Heterogeneity of Cancer Metabolism, 13-32, 2018
1542018
Discovery of 6-Diazo-5-oxo-l-norleucine (DON) Prodrugs with Enhanced CSF Delivery in Monkeys: A Potential Treatment for Glioblastoma
R Rais, A Jancarik, L Tenora, M Nedelcovych, J Alt, J Englert, C Rojas, ...
Journal of medicinal chemistry 59 (18), 8621-8633, 2016
1152016
Glucose metabolism in cancer: The Warburg effect and beyond
S Bose, C Zhang, A Le
Adv Exp Med Biol 1311, 3-15, 2021
1002021
Uncovering the role of N-acetyl-aspartyl-glutamate as a glutamate reservoir in cancer
T Nguyen, BJ Kirsch, R Asaka, K Nabi, A Quinones, J Tan, MJ Antonio, ...
Cell reports 27 (2), 491-501. e6, 2019
812019
Mitogen activated protein kinase activated protein kinase 2 regulates actin polymerization and vascular leak in ventilator associated lung injury
M Damarla, E Hasan, A Boueiz, A Le, HH Pae, C Montouchet, T Kolb, ...
PloS one 4 (2), e4600, 2009
812009
Alveolar cell apoptosis is dependent on p38 MAP kinase-mediated activation of xanthine oxidoreductase in ventilator-induced lung injury
A Le, R Damico, M Damarla, A Boueiz, HH Pae, J Skirball, E Hasan, ...
Journal of Applied Physiology 105 (4), 1282-1290, 2008
762008
Evaluation of LDH-A and Glutaminase Inhibition In Vivo by Hyperpolarized 13C-Pyruvate Magnetic Resonance Spectroscopy of Tumors
P Dutta, A Le, DL Vander Jagt, T Tsukamoto, GV Martinez, CV Dang, ...
Cancer research 73 (14), 4190-4195, 2013
752013
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