| Robust deep learning–based protein sequence design using ProteinMPNN J Dauparas, I Anishchenko, N Bennett, H Bai, RJ Ragotte, LF Milles, ... Science 378 (6615), 49-56, 2022 | 509 | 2022 |
| De novo design of protein structure and function with RFdiffusion JL Watson, D Juergens, NR Bennett, BL Trippe, J Yim, HE Eisenach, ... Nature 620 (7976), 1089-1100, 2023 | 290 | 2023 |
| Scaffolding protein functional sites using deep learning J Wang, S Lisanza, D Juergens, D Tischer, JL Watson, KM Castro, ... Science 377 (6604), 387-394, 2022 | 233 | 2022 |
| Molecular mechanism of extreme mechanostability in a pathogen adhesin LF Milles, K Schulten, HE Gaub, RC Bernardi Science 359 (6383), 1527-1533, 2018 | 195 | 2018 |
| Broadly applicable and accurate protein design by integrating structure prediction networks and diffusion generative models JL Watson, D Juergens, NR Bennett, BL Trippe, J Yim, HE Eisenach, ... BioRxiv, 2022.12. 09.519842, 2022 | 157 | 2022 |
| Hallucinating symmetric protein assemblies BIM Wicky, LF Milles, A Courbet, RJ Ragotte, J Dauparas, E Kinfu, S Tipps, ... Science 378 (6615), 56-61, 2022 | 117 | 2022 |
| Ultrastable cellulosome-adhesion complex tightens under load C Schoeler, KH Malinowska, RC Bernardi, LF Milles, MA Jobst, E Durner, ... Nature communications 5 (1), 5635, 2014 | 106 | 2014 |
| Structural and mechanistic insights into mechanoactivation of focal adhesion kinase MS Bauer, F Baumann, C Daday, P Redondo, E Durner, MA Jobst, ... Proceedings of the National Academy of Sciences 116 (14), 6766-6774, 2019 | 105 | 2019 |
| From genes to protein mechanics on a chip M Otten, W Ott, MA Jobst, LF Milles, T Verdorfer, DA Pippig, MA Nash, ... Nature methods 11 (11), 1127-1130, 2014 | 78 | 2014 |
| Elastin-like polypeptide linkers for single-molecule force spectroscopy W Ott, MA Jobst, MS Bauer, E Durner, LF Milles, MA Nash, HE Gaub ACS nano 11 (6), 6346-6354, 2017 | 71 | 2017 |
| Calcium stabilizes the strongest protein fold LF Milles, EM Unterauer, T Nicolaus, HE Gaub Nature communications 9 (1), 4764, 2018 | 50 | 2018 |
| Language models generalize beyond natural proteins R Verkuil, O Kabeli, Y Du, BIM Wicky, LF Milles, J Dauparas, D Baker, ... bioRxiv, 2022.12. 21.521521, 2022 | 47 | 2022 |
| Resolving dual binding conformations of cellulosome cohesin-dockerin complexes using single-molecule force spectroscopy MA Jobst, LF Milles, C Schoeler, W Ott, DB Fried, EA Bayer, HE Gaub, ... Elife 4, e10319, 2015 | 47 | 2015 |
| Monovalent Strep-Tactin for strong and site-specific tethering in nanospectroscopy F Baumann, MS Bauer, LF Milles, A Alexandrovich, HE Gaub, DA Pippig Nature Nanotechnology 11 (1), 89-94, 2016 | 44 | 2016 |
| Monodisperse measurement of the biotin-streptavidin interaction strength in a well-defined pulling geometry SM Sedlak, MS Bauer, C Kluger, LC Schendel, LF Milles, DA Pippig, ... PLoS One 12 (12), e0188722, 2017 | 43 | 2017 |
| Design of proteins presenting discontinuous functional sites using deep learning D Tischer, S Lisanza, J Wang, R Dong, I Anishchenko, LF Milles, ... Biorxiv, 2020.11. 29.402743, 2020 | 41 | 2020 |
| A tethered ligand assay to probe SARS-CoV-2: ACE2 interactions MS Bauer, S Gruber, A Hausch, PSFC Gomes, LF Milles, T Nicolaus, ... Proceedings of the National Academy of Sciences 119 (14), e2114397119, 2022 | 37 | 2022 |
| Deep learning methods for designing proteins scaffolding functional sites J Wang, S Lisanza, D Juergens, D Tischer, I Anishchenko, M Baek, ... BioRxiv, 2021.11. 10.468128, 2021 | 34 | 2021 |
| Different vinculin binding sites use the same mechanism to regulate directional force transduction C Kluger, L Braun, SM Sedlak, DA Pippig, MS Bauer, K Miller, LF Milles, ... Biophysical journal 118 (6), 1344-1356, 2020 | 33 | 2020 |
| Extreme mechanical stability in protein complexes LF Milles, HE Gaub Current Opinion in Structural Biology 60, 124-130, 2020 | 30 | 2020 |
Hermann E.GaubPhysics University MunichVerified email at lmu.de
