TGF-β signaling and epithelial–mesenchymal transition in cancer progression Y Katsuno, S Lamouille, R Derynck Current opinion in oncology 25 (1), 76-84, 2013 | 896 | 2013 |
Bone morphogenetic protein signaling enhances invasion and bone metastasis of breast cancer cells through Smad pathway Y Katsuno, A Hanyu, H Kanda, Y Ishikawa, F Akiyama, T Iwase, E Ogata, ... Oncogene 27 (49), 6322-6333, 2008 | 273 | 2008 |
Ki26894, a novel transforming growth factor‐β type I receptor kinase inhibitor, inhibits in vitro invasion and in vivo bone metastasis of a human breast cancer cell line S Ehata, A Hanyu, M Fujime, Y Katsuno, E Fukunaga, K Goto, Y Ishikawa, ... Cancer science 98 (1), 127-133, 2007 | 207 | 2007 |
TGF-β family signaling in stem cells M Sakaki-Yumoto, Y Katsuno, R Derynck Biochimica et Biophysica Acta (BBA)-General Subjects 1830 (2), 2280-2296, 2013 | 196 | 2013 |
Estrogen inhibits transforming growth factor β signaling by promoting Smad2/3 degradation I Ito, A Hanyu, M Wayama, N Goto, Y Katsuno, S Kawasaki, Y Nakajima, ... Journal of biological chemistry 285 (19), 14747-14755, 2010 | 167 | 2010 |
Chronic TGF-β exposure drives stabilized EMT, tumor stemness, and cancer drug resistance with vulnerability to bitopic mTOR inhibition Y Katsuno, DS Meyer, Z Zhang, KM Shokat, RJ Akhurst, K Miyazono, ... Science signaling 12 (570), eaau8544, 2019 | 166 | 2019 |
Intracellular and extracellular TGF-β signaling in cancer: some recent topics K Miyazono, Y Katsuno, D Koinuma, S Ehata, M Morikawa Frontiers of medicine 12, 387-411, 2018 | 133 | 2018 |
Coordinated expression of REG4 and aldehyde dehydrogenase 1 regulating tumourigenic capacity of diffuse‐type gastric carcinoma‐initiating cells is inhibited by TGF‐β Y Katsuno, S Ehata, M Yashiro, K Yanagihara, K Hirakawa, K Miyazono The Journal of pathology 228 (3), 391-404, 2012 | 119 | 2012 |
Arginine methylation initiates BMP-induced Smad signaling J Xu, AH Wang, J Oses-Prieto, K Makhijani, Y Katsuno, M Pei, L Yan, ... Molecular cell 51 (1), 5-19, 2013 | 104 | 2013 |
Epithelial plasticity, epithelial-mesenchymal transition, and the TGF-β family Y Katsuno, R Derynck Developmental cell 56 (6), 726-746, 2021 | 100 | 2021 |
Transforming growth factor-β decreases the cancer-initiating cell population within diffuse-type gastric carcinoma cells S Ehata, E Johansson, R Katayama, S Koike, A Watanabe, Y Hoshino, ... Oncogene 30 (14), 1693-1705, 2011 | 96 | 2011 |
Autocrine TGF-β protects breast cancer cells from apoptosis through reduction of BH3-only protein, Bim Y Hoshino, Y Katsuno, S Ehata, K Miyazono The journal of biochemistry 149 (1), 55-65, 2011 | 67 | 2011 |
Arginine methylation of SMAD7 by PRMT1 in TGF-β–induced epithelial–mesenchymal transition and epithelial stem-cell generation Y Katsuno, J Qin, J Oses-Prieto, H Wang, O Jackson-Weaver, T Zhang, ... Journal of Biological Chemistry 293 (34), 13059-13072, 2018 | 65 | 2018 |
Smad3‐mediated recruitment of the methyltransferase SETDB1/ESET controls Snail1 expression and epithelial–mesenchymal transition D Du, Y Katsuno, D Meyer, EH Budi, SH Chen, H Koeppen, H Wang, ... EMBO reports 19 (1), 135-155, 2018 | 65 | 2018 |
Smad4 decreases the population of pancreatic cancer–initiating cells through transcriptional repression of ALDH1A1 Y Hoshino, J Nishida, Y Katsuno, D Koinuma, T Aoki, N Kokudo, ... The American Journal of Pathology 185 (5), 1457-1470, 2015 | 62 | 2015 |
Prostate cancer cells and bone stromal cells mutually interact with each other through bone morphogenetic protein-mediated signals H Nishimori, S Ehata, HI Suzuki, Y Katsuno, K Miyazono Journal of Biological Chemistry 287 (24), 20037-20046, 2012 | 62 | 2012 |
ShcA protects against epithelial–mesenchymal transition through compartmentalized inhibition of TGF-β-induced Smad activation BP Muthusamy, EH Budi, Y Katsuno, MK Lee, SM Smith, AM Mirza, ... PLoS biology 13 (12), e1002325, 2015 | 53 | 2015 |
Chronic TGF-beta exposure drives stabilized EMT, tumor stemness and drug resistance with vulnerability to mTOR inhibition Y Katsuno, K Miyazono, R Derynck CANCER SCIENCE 112, 280-280, 2021 | | 2021 |
Chronic TGF-beta exposure drives stabilized and mTOR-dependent EMT and tumor stemness Y Katsuno, K Miyazono, R Derynck CANCER SCIENCE 109, 689-689, 2018 | | 2018 |
Prolonged exposure to TGF-beta stabilizes stem cell-like state of breast cancer cells and increases drug resistance Y Katsuno, K Miyazono, R Derynck CANCER SCIENCE 109, 486-486, 2018 | | 2018 |