Thomas Macartney
Thomas Macartney
Molecular Bilologist, University of Dundee
Email verificata su dundee.ac.uk
TitoloCitata daAnno
PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65
C Kondapalli, A Kazlauskaite, N Zhang, HI Woodroof, DG Campbell, ...
Open biology 2 (5), 120080, 2012
4652012
Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair
IM Muñoz, K Hain, AC Déclais, M Gardiner, GW Toh, L Sanchez-Pulido, ...
Molecular cell 35 (1), 116-127, 2009
3262009
Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2
C MacKay, AC Déclais, C Lundin, A Agostinho, AJ Deans, TJ MacArtney, ...
Cell 142 (1), 65-76, 2010
2802010
14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization
RJ Nichols, N Dzamko, NA Morrice, DG Campbell, M Deak, A Ordureau, ...
Biochemical Journal 430 (3), 393-404, 2010
2582010
The CUL3–KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt …
A Ohta, FR Schumacher, Y Mehellou, C Johnson, A Knebel, TJ Macartney, ...
Biochemical Journal 451 (1), 111-122, 2013
1542013
Cooperative control of holliday junction resolution and DNA repair by the SLX1 and MUS81-EME1 nucleases
D Castor, N Nair, AC Déclais, C Lachaud, R Toth, TJ Macartney, ...
Molecular cell 52 (2), 221-233, 2013
1192013
The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+–Cl co-transporters
P De Los Heros, DR Alessi, R Gourlay, DG Campbell, M Deak, ...
Biochemical Journal 458 (3), 559-573, 2014
1162014
DVC1 (C1orf124) recruits the p97 protein segregase to sites of DNA damage
EJ Davis, C Lachaud, P Appleton, TJ Macartney, I Näthke, J Rouse
Nature structural & molecular biology 19 (11), 1093, 2012
1152012
Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1
YC Lai, C Kondapalli, R Lehneck, JB Procter, BD Dill, HI Woodroof, ...
The EMBO journal 34 (22), 2840-2861, 2015
1002015
USP11 augments TGFβ signalling by deubiquitylating ALK5
MA Al-Salihi, L Herhaus, T Macartney, GP Sapkota
Open biology 2 (6), 120063, 2012
932012
Phosphorylation of Parkin at Serine65 is essential for activation: elaboration of a Miro1 substrate-based assay of Parkin E3 ligase activity
A Kazlauskaite, V Kelly, C Johnson, C Baillie, CJ Hastie, M Peggie, ...
Open biology 4 (3), 130213, 2014
782014
Identification of the MMS22L-TONSL complex that promotes homologous recombination
E Duro, C Lundin, K Ask, L Sanchez-Pulido, TJ MacArtney, R Toth, ...
Molecular cell 40 (4), 632-644, 2010
782010
OTUB1 enhances TGFβ signalling by inhibiting the ubiquitylation and degradation of active SMAD2/3
L Herhaus, M Al-Salihi, T Macartney, S Weidlich, GP Sapkota
Nature communications 4 (1), 1-13, 2013
742013
Phosphorylation of synaptic vesicle protein 2A at Thr84 by casein kinase 1 family kinases controls the specific retrieval of synaptotagmin-1
N Zhang, SL Gordon, MJ Fritsch, N Esoof, DG Campbell, R Gourlay, ...
Journal of Neuroscience 35 (6), 2492-2507, 2015
422015
The Parkinson's disease VPS35 [D620N] mutation enhances LRRK2-mediated Rab protein phosphorylation in mouse and human
R Mir, F Tonelli, P Lis, T Macartney, NK Polinski, TN Martinez, MY Chou, ...
Biochemical Journal 475 (11), 1861-1883, 2018
382018
Roles of the TRAF6 and Pellino E3 ligases in MyD88 and RANKL signaling
S Strickson, CH Emmerich, ETH Goh, J Zhang, IR Kelsall, T Macartney, ...
Proceedings of the National Academy of Sciences 114 (17), E3481-E3489, 2017
372017
Distinct functional roles for the two SLX4 ubiquitin-binding UBZ domains mutated in Fanconi anemia
C Lachaud, D Castor, K Hain, I Muñoz, J Wilson, TJ MacArtney, ...
J Cell Sci 127 (13), 2811-2817, 2014
352014
Rapid generation of endogenously driven transcriptional reporters in cells through CRISPR/Cas9
A Rojas-Fernandez, L Herhaus, T Macartney, C Lachaud, RT Hay, ...
Scientific reports 5, 9811, 2015
322015
USP45 deubiquitylase controls ERCC1–XPF endonuclease‐mediated DNA damage responses
AB Perez‐Oliva, C Lachaud, P Szyniarowski, I Muñoz, T Macartney, ...
The EMBO journal 34 (3), 326-343, 2015
312015
Family with sequence similarity 60A (FAM60A) protein is a cell cycle-fluctuating regulator of the SIN3-HDAC1 histone deacetylase complex
IM Muñoz, T MacArtney, L Sanchez-Pulido, CP Ponting, S Rocha, ...
Journal of Biological Chemistry 287 (39), 32346-32353, 2012
302012
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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