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Aldo Di Leonardo
Aldo Di Leonardo
Professor of Genetics, Dept STEBICEF, University of Palermo, Italy.
Email verificata su unipa.it
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DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts.
A Di Leonardo, SP Linke, K Clarkin, GM Wahl
Genes & development 8 (21), 2540-2551, 1994
15781994
A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage.
SP Linke, KC Clarkin, A Di Leonardo, A Tsou, GM Wahl
Genes & development 10 (8), 934-947, 1996
7051996
DNA rereplication in the presence of mitotic spindle inhibitors in human and mouse fibroblasts lacking either p53 or pRb function
AD Leonardo, SH Khan, SP Linke, V Greco, G Seidita, GM Wahl
Cancer research 57 (6), 1013-1019, 1997
2791997
CENPA overexpression promotes genome instability in pRb-depleted human cells
A Amato, T Schillaci, L Lentini, A Di Leonardo
Molecular cancer 8, 1-14, 2009
1462009
The mitotic kinase Aurora-A promotes distant metastases by inducing epithelial-to-mesenchymal transition in ERα+ breast cancer cells
AB D'assoro, C Quatraro, A Amato, M Opyrchal, A Leontovich, Y Ikeda, ...
Oncogene 33 (5), 599-610, 2014
1382014
RB acute loss induces centrosome amplification and aneuploidy in murine primary fibroblasts
F Iovino, L Lentini, A Amato, A Di Leonardo
Molecular cancer 5, 1-11, 2006
1042006
Toward a rationale for the PTC124 (Ataluren) promoted readthrough of premature stop codons: a computational approach and GFP-reporter cell-based assay
L Lentini, R Melfi, A Di Leonardo, A Spinello, G Barone, A Pace, ...
Molecular pharmaceutics 11 (3), 653-664, 2014
962014
NOTCH3 expression is linked to breast cancer seeding and distant metastasis
AA Leontovich, M Jalalirad, JL Salisbury, L Mills, C Haddox, M Schroeder, ...
Breast Cancer Research 20, 1-19, 2018
722018
Simultaneous Aurora-A/STK15 overexpression and centrosome amplification induce chromosomal instability in tumour cells with a MIN phenotype
L Lentini, A Amato, T Schillaci, A Di Leonardo
BMC cancer 7, 1-13, 2007
672007
Enhancement of premature stop codon readthrough in the CFTR gene by Ataluren (PTC124) derivatives
I Pibiri, L Lentini, R Melfi, G Gallucci, A Pace, A Spinello, G Barone, ...
European journal of medicinal chemistry 101, 236-244, 2015
602015
RNAi mediated acute depletion of retinoblastoma protein (pRb) promotes aneuploidy in human primary cells via micronuclei formation
A Amato, L Lentini, T Schillaci, F Iovino, A Di Leonardo
BMC cell biology 10, 1-13, 2009
582009
MAD2 depletion triggers premature cellular senescence in human primary fibroblasts by activating a p53 pathway preventing aneuploid cells propagation
L Lentini, V Barra, T Schillaci, A Di Leonardo
Journal of cellular physiology 227 (9), 3324-3332, 2012
442012
Retinoblastoma epidemiology: does the evidence matter?
D Mastrangelo, S De Francesco, A Di Leonardo, L Lentini, ...
European Journal of Cancer 43 (10), 1596-1603, 2007
412007
Strategies against nonsense: oxadiazoles as translational readthrough-inducing drugs (TRIDs)
A Campofelice, L Lentini, A Di Leonardo, R Melfi, M Tutone, A Pace, ...
International journal of molecular sciences 20 (13), 3329, 2019
402019
Expression of the kinetochore protein Hec1 during the cell cycle in normal and cancer cells and its regulation by the pRb pathway
C Ferretti, P Totta, M Fiore, M Mattiuzzo, T Schillaci, R Ricordye, ...
Cell Cycle 9 (20), 4174-4182, 2010
402010
Exploring the readthrough of nonsense mutations by non-acidic Ataluren analogues selected by ligand-based virtual screening
I Pibiri, L Lentini, M Tutone, R Melfi, A Pace, A Di Leonardo
European Journal of Medicinal Chemistry 122, 429-435, 2016
352016
Bypass of cell cycle arrest induced by transient DNMT1 post-transcriptional silencing triggers aneuploidy in human cells
V Barra, T Schillaci, L Lentini, G Costa, A Di Leonardo
Cell division 7, 1-12, 2012
352012
Cell cycle regulation of gene amplification
A Di Leonardo, SP Linke, Y Yin, GM Wahl
Cold Spring Harbor Symposia on Quantitative Biology 58, 655-667, 1993
351993
DNA demethylation caused by 5-Aza-2′-deoxycytidine induces mitotic alterations and aneuploidy
G Costa, V Barra, L Lentini, D Cilluffo, A Di Leonardo
Oncotarget 7 (4), 3726, 2016
332016
The retinoblastoma paradigm revisited
D Mastrangelo, S De Francesco, A Di Leonardo, L Lentini, ...
Med Sci Monit 14 (12), 231-240, 2008
332008
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
Articoli 1–20