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W. Seth Horne
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Foldamers with heterogeneous backbones
WS Horne, SH Gellman
Accounts of chemical research 41 (10), 1399-1408, 2008
7612008
Heterocyclic peptide backbone modifications in an α-helical coiled coil
WS Horne, MK Yadav, CD Stout, MR Ghadiri
Journal of the American Chemical Society 126 (47), 15366-15367, 2004
6012004
A heterocyclic peptide nanotube
WS Horne, CD Stout, MR Ghadiri
Journal of the American Chemical Society 125 (31), 9372-9376, 2003
4282003
Structural and biological mimicry of protein surface recognition by α/β-peptide foldamers
WS Horne, LM Johnson, TJ Ketas, PJ Klasse, M Lu, JP Moore, ...
Proceedings of the National Academy of Sciences 106 (35), 14751-14756, 2009
3132009
Design of self‐assembling peptide nanotubes with delocalized electronic states
N Ashkenasy, WS Horne, MR Ghadiri
Small 2 (1), 99-102, 2006
2532006
Helix bundle quaternary structure from α/β-peptide foldamers
WS Horne, JL Price, JL Keck, SH Gellman
Journal of the American Chemical Society 129 (14), 4178-4180, 2007
2372007
Efficient Route to C2 Symmetric Heterocyclic Backbone Modified Cyclic Peptides
JH van Maarseveen, WS Horne, MR Ghadiri
Organic letters 7 (20), 4503-4506, 2005
1882005
Sequence-based design of α/β-peptide foldamers that mimic BH3 domains
WS Horne, MD Boersma, MA Windsor, SH Gellman
Angewandte Chemie (International ed. in English) 47 (15), 2853, 2008
1802008
Antiviral cyclic D,L-α-peptides: Targeting a general biochemical pathway in virus infections
WS Horne, CM Wiethoff, C Cui, KM Wilcoxen, M Amorin, MR Ghadiri, ...
Bioorganic & medicinal chemistry 13 (17), 5145-5153, 2005
1762005
The Double‐Histidine Cu2+‐Binding Motif: A Highly Rigid, Site‐Specific Spin Probe for Electron Spin Resonance Distance Measurements
TF Cunningham, MR Putterman, A Desai, WS Horne, S Saxena
Angewandte Chemie 127 (21), 6428-6432, 2015
1742015
Probing the Bioactive Conformation of an Archetypal Natural Product HDAC Inhibitor with Conformationally Homogeneous Triazole‐Modified Cyclic Tetrapeptides
WS Horne, CA Olsen, JM Beierle, A Montero, MR Ghadiri
Angewandte Chemie International Edition 48 (26), 4718-4724, 2009
1742009
Evaluation of diverse α/β-backbone patterns for functional α-helix mimicry: analogues of the Bim BH3 domain
MD Boersma, HS Haase, KJ Peterson-Kaufman, EF Lee, OB Clarke, ...
Journal of the American Chemical Society 134 (1), 315-323, 2012
1642012
Modulating Charge Transfer through Cyclic D,L‐α‐Peptide Self‐Assembly
WS Horne, N Ashkenasy, MR Ghadiri
Chemistry-A European Journal 11 (4), 1137-1144, 2005
1522005
Interplay among side chain sequence, backbone composition, and residue rigidification in polypeptide folding and assembly
WS Horne, JL Price, SH Gellman
Proceedings of the National Academy of Sciences 105 (27), 9151-9156, 2008
1392008
Peptide backbone composition and protease susceptibility: impact of modification type, position, and tandem substitution
HM Werner, CC Cabalteja, WS Horne
ChemBioChem 17 (8), 712-718, 2016
1342016
Peptide and peptoid foldamers in medicinal chemistry
WS Horne
Expert Opinion on Drug Discovery 6 (12), 1247-1262, 2011
1212011
Discrete heterogeneous quaternary structure formed by α/β-peptide foldamers and α-peptides
JL Price, WS Horne, SH Gellman
Journal of the American Chemical Society 129 (20), 6376-6377, 2007
1052007
β-hairpin-mediated nucleation of polyglutamine amyloid formation
K Kar, CL Hoop, KW Drombosky, MA Baker, R Kodali, I Arduini, ...
Journal of molecular biology 425 (7), 1183-1197, 2013
1022013
Proteomimetics as protein-inspired scaffolds with defined tertiary folding patterns
WS Horne, TN Grossmann
Nature chemistry 12 (4), 331-337, 2020
1012020
Total synthesis and biological evaluation of pederin, psymberin, and highly potent analogs
S Wan, F Wu, JC Rech, ME Green, R Balachandran, WS Horne, BW Day, ...
Journal of the American Chemical Society 133 (41), 16668-16679, 2011
1012011
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Articles 1–20