Eva Gronroos
Eva Gronroos
Email verificata su crick.ac.uk
Citata da
Citata da
Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
M Gerlinger, AJ Rowan, S Horswell, J Larkin, D Endesfelder, E Gronroos, ...
N Engl j Med 366, 883-892, 2012
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution
C Abbosh, NJ Birkbak, GA Wilson, M Jamal-Hanjani, T Constantin, ...
Nature 545 (7655), 446-451, 2017
Spatial and temporal diversity in genomic instability processes defines lung cancer evolution
EC de Bruin, N McGranahan, R Mitter, M Salm, DC Wedge, L Yates, ...
Science 346 (6206), 251-256, 2014
Replication stress links structural and numerical cancer chromosomal instability
RA Burrell, SE McClelland, D Endesfelder, P Groth, MC Weller, N Shaikh, ...
Nature 494 (7438), 492-496, 2013
Control of Smad7 stability by competition between acetylation and ubiquitination
E Gronroos, U Hellman, CH Heldin, J Ericsson
Molecular cell 10 (3), 483-493, 2002
Deterministic evolutionary trajectories influence primary tumor growth: TRACERx renal
S Turajlic, H Xu, K Litchfield, A Rowan, S Horswell, T Chambers, ...
Cell 173 (3), 595-610. e11, 2018
Tolerance of whole-genome doubling propagates chromosomal instability and accelerates cancer genome evolution
SM Dewhurst, N McGranahan, RA Burrell, AJ Rowan, E Grönroos, ...
Cancer discovery 4 (2), 175-185, 2014
Pyk2 and FAK regulate neurite outgrowth induced by growth factors and integrins
I Ivankovic-Dikic, E Gronroos, A Blaukat, BU Barth, I Dikic
Nature cell biology 2 (9), 574-581, 2000
Adaptor proteins Grb2 and Crk couple Pyk2 with activation of specific mitogen-activated protein kinase cascades
A Blaukat, I Ivankovic-Dikic, E Grönroos, F Dolfi, G Tokiwa, K Vuori, ...
Journal of Biological Chemistry 274 (21), 14893-14901, 1999
Coactivator-dependent acetylation stabilizes members of the SREBP family of transcription factors
V Giandomenico, M Simonsson, E Gronroos, J Ericsson
Molecular and cellular biology 23 (7), 2587, 2003
YY1 inhibits the activation of the p53 tumor suppressor in response to genotoxic stress
E Grönroos, AA Terentiev, T Punga, J Ericsson
Proceedings of the National Academy of Sciences 101 (33), 12165-12170, 2004
The balance between acetylation and deacetylation controls Smad7 stability
M Simonsson, CH Heldin, J Ericsson, E Grönroos
Journal of Biological Chemistry 280 (23), 21797-21803, 2005
Requirement for interaction of PI3-kinase p110α with RAS in lung tumor maintenance
E Castellano, C Sheridan, MZ Thin, E Nye, B Spencer-Dene, ...
Cancer cell 24 (5), 617-630, 2013
SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair
N Kanu, E Grönroos, P Martinez, RA Burrell, XY Goh, J Bartkova, ...
Oncogene 34 (46), 5699-5708, 2015
The DNA binding activities of Smad2 and Smad3 are regulated by coactivator-mediated acetylation
M Simonsson, M Kanduri, E Gronroos, CH Heldin, J Ericsson
Journal of Biological Chemistry 281 (52), 39870-39880, 2006
Transforming growth factor β inhibits bone morphogenetic protein-induced transcription through novel phosphorylated Smad1/5-Smad3 complexes
E Grönroos, IJ Kingston, A Ramachandran, RA Randall, P Vizán, CS Hill
Molecular and cellular biology 32 (14), 2904-2916, 2012
Development of synchronous VHL syndrome tumors reveals contingencies and constraints to tumor evolution
R Fisher, S Horswell, A Rowan, MP Salm, EC de Bruin, S Gulati, ...
Genome biology 15 (8), 1-15, 2014
BCL9L dysfunction impairs caspase-2 expression permitting aneuploidy tolerance in colorectal cancer
C López-García, L Sansregret, E Domingo, N McGranahan, S Hobor, ...
Cancer cell 31 (1), 79-93, 2017
Leukotriene D4 and E4 induce transmembrane signaling in human epithelial cells. Single cell analysis reveals diverse pathways at the G-protein level for the influx and the …
A Sjölander, E Grönroos, S Hammarström, T Andersson
Journal of Biological Chemistry 265 (34), 20976-20981, 1990
Pervasive chromosomal instability and karyotype order in tumour evolution
TBK Watkins, EL Lim, M Petkovic, S Elizalde, NJ Birkbak, GA Wilson, ...
Nature 587 (7832), 126-132, 2020
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