Andreas Pluckthun
TitleCited byYear
In vitro selection and evolution of functional proteins by using ribosome display
J Hanes, A Plückthun
Proceedings of the National Academy of Sciences 94 (10), 4937-4942, 1997
15001997
Assembly of a functional immunoglobulin Fv fragment in Escherichia coli
A Skerra, A Pluckthun
Science 240 (4855), 1038-1041, 1988
14141988
Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides
A Knappik, L Ge, A Honegger, P Pack, M Fischer, GÈ Wellnhofer, A Hoess, ...
Journal of molecular biology 296 (1), 57-86, 2000
9672000
Engineering novel binding proteins from nonimmunoglobulin domains
HK Binz, P Amstutz, A Plückthun
Nature biotechnology 23 (10), 1257, 2005
7342005
High-affinity binders selected from designed ankyrin repeat protein libraries
HK Binz, P Amstutz, A Kohl, MT Stumpp, C Briand, P Forrer, MG Grütter, ...
Nature biotechnology 22 (5), 575, 2004
6652004
In vitro generated antibodies specific for telomeric guanine-quadruplex DNA react with Stylonychia lemnae macronuclei
C Schaffitzel, I Berger, J Postberg, J Hanes, HJ Lipps, A Plückthun
Proceedings of the National Academy of Sciences 98 (15), 8572-8577, 2001
6472001
Induction and exhaustion of lymphocytic choriomeningitis virus–specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I …
A Gallimore, A Glithero, A Godkin, AC Tissot, A Plückthun, T Elliott, ...
Journal of Experimental Medicine 187 (9), 1383-1393, 1998
6471998
Stability engineering of antibody single-chain Fv fragments
A Wörn, A Plückthun
Journal of molecular biology 305 (5), 989-1010, 2001
6392001
A comparison of strategies to stabilize immunoglobulin Fv-fragments
R Glockshuber, M Malia, I Pfitzinger, A Plueckthun
Biochemistry 29 (6), 1362-1367, 1990
6281990
Reliable cloning of functional antibody variable domains from hybridomas and spleen cell repertoires employing a reengineered phage display system
A Krebber, S Bornhauser, J Burmester, A Honegger, J Willuda, ...
Journal of immunological methods 201 (1), 35-55, 1997
6011997
Designing repeat proteins: well-expressed, soluble and stable proteins from combinatorial libraries of consensus ankyrin repeat proteins
HK Binz, MT Stumpp, P Forrer, P Amstutz, A Plückthun
Journal of molecular biology 332 (2), 489-503, 2003
5252003
Picomolar affinity antibodies from a fully synthetic naive library selected and evolved by ribosome display
J Hanes, C Schaffitzel, A Knappik, A Plückthun
Nature biotechnology 18 (12), 1287, 2000
4922000
New protein engineering approaches to multivalent and bispecific antibody fragments
A Plückthun, P Pack
Immunotechnology 3 (2), 83-105, 1997
4631997
Miniantibodies: use of amphipathic helixes to produce functional, flexibly linked dimeric FV fragments with high avidity in Escherichia coli
P Pack, A Plueckthun
Biochemistry 31 (6), 1579-1584, 1992
4251992
In-vitro protein evolution by ribosome display and mRNA display
D Lipovsek, A Plückthun
Journal of immunological methods 290 (1-2), 51-67, 2004
4212004
Ribosome display efficiently selects and evolves high-affinity antibodies in vitro from immune libraries
J Hanes, L Jermutus, S Weber-Bornhauser, HR Bosshard, A Plückthun
Proceedings of the National Academy of Sciences 95 (24), 14130-14135, 1998
4041998
BIACORE analysis of histidine-tagged proteins using a chelating NTA sensor chip
L Nieba, SE Nieba-Axmann, A Persson, M Hämäläinen, F Edebratt, ...
Analytical biochemistry 252 (2), 217-228, 1997
3981997
Reproducibility: Standardize antibodies used in research
A Bradbury, A Plückthun
Nature News 518 (7537), 27, 2015
3712015
Stable one-step technetium-99m labeling of His-tagged recombinant proteins with a novel Tc (I)–carbonyl complex
R Waibel, R Alberto, J Willuda, R Finnern, R Schibli, A Stichelberger, ...
Nature biotechnology 17 (9), 897, 1999
3561999
Sequence statistics reliably predict stabilizing mutations in a protein domain
B Steipe, B Schiller, A Plückthun, S Steinbacher
Journal of molecular biology 240 (3), 188-192, 1994
3551994
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Articles 1–20