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Helen Woodroof
Helen Woodroof
Email verificata su dundee.ac.uk
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PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65
C Kondapalli, A Kazlauskaite, N Zhang, HI Woodroof, DG Campbell, ...
Open biology 2 (5), 120080, 2012
9202012
Phosphoproteomic screening identifies Rab GTP ases as novel downstream targets of PINK 1
YC Lai, C Kondapalli, R Lehneck, JB Procter, BD Dill, HI Woodroof, ...
The EMBO journal 34 (22), 2840-2861, 2015
1862015
Phosphorylation of Parkin at Serine65 is essential for activation: elaboration of a Miro1 substrate-based assay of Parkin E3 ligase activity
A Kazlauskaite, V Kelly, C Johnson, C Baillie, CJ Hastie, M Peggie, ...
Open biology 4 (3), 130213, 2014
1462014
Discovery of catalytically active orthologues of the Parkinson's disease kinase PINK1: analysis of substrate specificity and impact of mutations
HI Woodroof, JH Pogson, M Begley, LC Cantley, M Deak, DG Campbell, ...
Open biology 1 (3), 110012, 2011
1062011
TigarB causes mitochondrial dysfunction and neuronal loss in PINK1 deficiency
LJ Flinn, M Keatinge, S Bretaud, H Mortiboys, H Matsui, E De Felice, ...
Annals of neurology 74 (6), 837-847, 2013
952013
Structure of PINK1 and mechanisms of Parkinson's disease-associated mutations
A Kumar, J Tamjar, AD Waddell, HI Woodroof, OG Raimi, AM Shaw, ...
Elife 6, e29985, 2017
942017
Kinase and channel activity of TRPM6 are co-ordinated by a dimerization motif and pocket interaction
J van der Wijst, MG Blanchard, HI Woodroof, TJ Macartney, R Gourlay, ...
Biochemical Journal 460 (2), 165-175, 2014
172014
.(2012) PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65
C Kondapalli, A Kazlauskaite, N Zhang, HI Woodroof, DG Campbell, ...
Open Biol 2, 120080, 0
5
Biochemical Characterisation of the Parkinson's Disease-associated Kinase PINK1: Insights from the Insect World
HI Woodroof
University of Dundee, 2014
2014
Kinase and channel activity of TRPM6 are co-ordinated by a dimerization motif and pocket interaction.
J Wijst, MG Blanchard, HI Woodroof, TJ Macartney, R Gourlay, ...
2014
PINK1 is activated by mitochondrial membrane potential
R Alessi, MMK Muqit, R Gourlay, L Burchell, H Walden, TJ Macartney, ...
2012
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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