BRCA1 mutation-specific responses to 53BP1 loss-induced homologous recombination and PARP inhibitor resistance J Nacson, JJ Krais, AJ Bernhardy, E Clausen, W Feng, Y Wang, E Nicolas, ... Cell reports 24 (13), 3513-3527. e7, 2018 | 86 | 2018 |
Gene expression and mutation-guided synthetic lethality eradicates proliferating and quiescent leukemia cells M Nieborowska-Skorska, K Sullivan, Y Dasgupta, ... The Journal of clinical investigation 127 (6), 2392-2406, 2017 | 70 | 2017 |
RET-mediated autophagy suppression as targetable co-dependence in acute myeloid leukemia S Rudat, A Pfaus, YY Cheng, J Holtmann, JM Ellegast, C Buehler, ... Leukemia 32 (10), 2189-2202, 2018 | 64 | 2018 |
JUN is a key transcriptional regulator of the unfolded protein response in acute myeloid leukemia C Zhou, E Martinez, D Di Marcantonio, N Solanki-Patel, T Aghayev, S Peri, ... Leukemia 31 (5), 1196-1205, 2017 | 63 | 2017 |
Hydrogen sulfide inhibits IL-8 expression in human keratinocytes via MAP kinase signaling P Mirandola, G Gobbi, C Micheloni, M Vaccarezza, D Di Marcantonio, ... Laboratory Investigation 91 (8), 1188-1194, 2011 | 49 | 2011 |
BRCA1 mutational complementation induces synthetic viability J Nacson, D Di Marcantonio, Y Wang, AJ Bernhardy, E Clausen, X Hua, ... Molecular cell 78 (5), 951-959. e6, 2020 | 42 | 2020 |
ATF3 coordinates serine and nucleotide metabolism to drive cell cycle progression in acute myeloid leukemia D Di Marcantonio, E Martinez, JS Kanefsky, JM Huhn, R Gabbasov, ... Molecular cell 81 (13), 2752-2764. e6, 2021 | 34 | 2021 |
MLL-AF9 leukemias are sensitive to PARP1 inhibitors combined with cytotoxic drugs S Maifrede, E Martinez, M Nieborowska-Skorska, D Di Marcantonio, ... Blood advances 1 (19), 1467-1472, 2017 | 28 | 2017 |
TET2 and DNMT3A Mutations Exert Divergent Effects on DNA Repair and Sensitivity of Leukemia Cells to PARP Inhibitors S Maifrede, BV Le, M Nieborowska-Skorska, K Golovine, K Sullivan-Reed, ... Cancer research 81 (19), 5089-5101, 2021 | 27 | 2021 |
The role of PKCε-dependent signaling for cardiac differentiation D Galli, G Gobbi, C Carrubbi, D Di Marcantonio, L Benedetti, ... Histochemistry and cell biology 139, 35-46, 2013 | 27 | 2013 |
Protein kinase Cε regulates proliferation and cell sensitivity to TGF-1β of CD4+ T lymphocytes: implications for Hashimoto thyroiditis P Mirandola, G Gobbi, E Masselli, C Micheloni, D Di Marcantonio, ... The Journal of Immunology 187 (9), 4721-4732, 2011 | 27 | 2011 |
Protein kinase C epsilon is a key regulator of mitochondrial redox homeostasis in acute myeloid leukemia D Di Marcantonio, E Martinez, S Sidoli, J Vadaketh, ... Clinical Cancer Research 24 (3), 608-618, 2018 | 26 | 2018 |
The-2518 A/G polymorphism of the monocyte chemoattractant protein-1 as a candidate genetic predisposition factor for secondary myelofibrosis and biomarker of disease severity E Masselli, C Carubbi, B Cambò, G Pozzi, G Gobbi, P Mirandola, E Follini, ... Leukemia 32 (10), 2266-2270, 2018 | 19 | 2018 |
PKCε as a novel promoter of skeletal muscle differentiation and regeneration D Di Marcantonio, D Galli, C Carubbi, G Gobbi, V Queirolo, S Martini, ... Experimental cell research 339 (1), 10-19, 2015 | 19 | 2015 |
TRAIL up‐regulation must be accompanied by a reciprocal PKCε down‐regulation during differentiation of colonic epithelial cell: Implications for colorectal cancer cell … G Gobbi, D Di Marcantonio, C Micheloni, C Carubbi, D Galli, ... Journal of cellular physiology 227 (2), 630-638, 2012 | 18 | 2012 |
The SAGA complex regulates early steps in transcription via its deubiquitylase module subunit USP22 TJ Stanek, VJ Gennaro, MA Tracewell, D Di Marcantonio, KL Pauley, ... The EMBO Journal 40 (16), e102509, 2021 | 9 | 2021 |
C-Jun regulates ER stress signaling to promote chemotherapy resistance in acute myeloid leukemia C Zhou, D Di Marcantonio, E Martinez, N Solanki-Patel, S Peri, C Scholl, ... Blood 126 (23), 2464, 2015 | 2 | 2015 |
TET2 and DNMT3A Mutations Exert Divergent Effects on DNA Repair and Sensitivity of Leukemia Cells to PARP Inhibitors S Maifrede, BV Le, M Nieborowska-Skorska, K Golovine, K Sullivan-Reed, ... Blood 136, 4, 2020 | 1 | 2020 |
Disruption of polyunsaturated fatty acid biosynthesis drives STING-dependent acute myeloid leukemia cell maturation and death J Kanefsky, M Basse, J Sokei, O di Martino, L Valin, Y Jaspers, E Martinez, ... Journal of Biological Chemistry 300 (5), 107214, 2024 | | 2024 |
Quantitative, titratable and high-throughput reporter assays to measure DNA double strand break repair activity in cells E Rajendra, D Grande, B Mason, D Di Marcantonio, L Armstrong, G Hewitt, ... Nucleic Acids Research 52 (4), 1736-1752, 2024 | | 2024 |