Specificity, cross-reactivity, and function of antibodies elicited by Zika virus infection K Stettler, M Beltramello, DA Espinosa, V Graham, A Cassotta, S Bianchi, ... Science 353 (6301), 823-826, 2016 | 842 | 2016 |
The human immune response to Dengue virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity M Beltramello, KL Williams, CP Simmons, A Macagno, L Simonelli, ... Cell host & microbe 8 (3), 271-283, 2010 | 689 | 2010 |
Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery F Fumagalli, J Noack, TJ Bergmann, E Cebollero, GB Pisoni, E Fasana, ... Nature cell biology 18 (11), 1173-1184, 2016 | 383 | 2016 |
Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus D Corti, J Zhao, M Pedotti, L Simonelli, S Agnihothram, C Fett, ... Proceedings of the National Academy of Sciences 112 (33), 10473-10478, 2015 | 225 | 2015 |
Balance of anti-CD123 chimeric antigen receptor binding affinity and density for the targeting of acute myeloid leukemia S Arcangeli, MC Rotiroti, M Bardelli, L Simonelli, CF Magnani, A Biondi, ... Molecular therapy 25 (8), 1933-1945, 2017 | 160 | 2017 |
A human bi-specific antibody against Zika virus with high therapeutic potential J Wang, M Bardelli, DA Espinosa, M Pedotti, TS Ng, S Bianchi, ... Cell 171 (1), 229-241. e15, 2017 | 139 | 2017 |
Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice R De Gasparo, M Pedotti, L Simonelli, P Nickl, F Muecksch, I Cassaniti, ... Nature 593 (7859), 424-428, 2021 | 111 | 2021 |
Computational docking of antibody-antigen complexes, opportunities and pitfalls illustrated by influenza hemagglutinin M Pedotti, L Simonelli, E Livoti, L Varani International journal of molecular sciences 12 (1), 226-251, 2011 | 91 | 2011 |
SARS-CoV-2 neutralizing human recombinant antibodies selected from pre-pandemic healthy donors binding at RBD-ACE2 interface F Bertoglio, D Meier, N Langreder, S Steinke, U Rand, L Simonelli, ... Nature communications 12 (1), 1577, 2021 | 82 | 2021 |
Epitope mapping by solution NMR spectroscopy M Bardelli, E Livoti, L Simonelli, M Pedotti, A Moraes, AP Valente, ... Journal of Molecular Recognition 28 (6), 393-400, 2015 | 54 | 2015 |
Rational engineering of a human anti-dengue antibody through experimentally validated computational docking L Simonelli, M Pedotti, M Beltramello, E Livoti, L Calzolai, F Sallusto, ... PloS one 8 (2), e55561, 2013 | 43 | 2013 |
Human neutralizing antibodies to cold linear epitopes and subdomain 1 of the SARS-CoV-2 spike glycoprotein F Bianchini, V Crivelli, ME Abernathy, C Guerra, M Palus, J Muri, ... Science immunology 8 (81), eade0958, 2023 | 38 | 2023 |
Rapid structural characterization of human antibody–antigen complexes through experimentally validated computational docking L Simonelli, M Beltramello, Z Yudina, A Macagno, L Calzolai, L Varani Journal of molecular biology 396 (5), 1491-1507, 2010 | 30 | 2010 |
Humoral and cell-mediated response against SARS-CoV-2 variants elicited by mRNA vaccine BNT162b2 in healthcare workers: a longitudinal observational study I Cassaniti, F Bergami, E Percivalle, E Gabanti, JC Sammartino, A Ferrari, ... Clinical Microbiology and Infection 28 (2), 301. e1-301. e8, 2022 | 25 | 2022 |
A bispecific immunotweezer prevents soluble PrP oligomers and abolishes prion toxicity M Bardelli, K Frontzek, L Simonelli, S Hornemann, M Pedotti, F Mazzola, ... PLoS pathogens 14 (10), e1007335, 2018 | 22 | 2018 |
Altered cellular distribution and sub-cellular sorting of doppel (Dpl) protein in human astrocytoma cell lines E Sbalchiero, A Azzalin, S Palumbo, G Barbieri, A Arias, L Simonelli, ... Analytical Cellular Pathology 30 (4), 337-347, 2008 | 21 | 2008 |
A conformational switch controlling the toxicity of the prion protein K Frontzek, M Bardelli, A Senatore, A Henzi, RR Reimann, S Bedir, ... Nature Structural & Molecular Biology 29 (8), 831-840, 2022 | 19 | 2022 |
Rational engineering of the lccβ T. versicolor laccase for the mediator-less oxidation of large polycyclic aromatic hydrocarbons A Chiadò, F Bosco, M Bardelli, L Simonelli, M Pedotti, L Marmo, L Varani Computational and Structural Biotechnology Journal 19, 2213-2222, 2021 | 17 | 2021 |
Antibody binding modulates conformational exchange in domain III of dengue virus E protein AH Moraes, L Simonelli, M Pedotti, FCL Almeida, L Varani, AP Valente Journal of virology 90 (4), 1802-1811, 2016 | 14 | 2016 |
Mapping antibody epitopes by solution NMR spectroscopy: practical considerations L Simonelli, M Pedotti, M Bardelli, S Jurt, O Zerbe, L Varani Epitope mapping protocols, 29-51, 2018 | 13 | 2018 |