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Luca Simonelli
Luca Simonelli
PhD, Institure for Research in Biomedicine, Usi, Bellinzona
Email verificata su irb.usi.ch - Home page
Titolo
Citata da
Citata da
Anno
Specificity, cross-reactivity, and function of antibodies elicited by Zika virus infection
K Stettler, M Beltramello, DA Espinosa, V Graham, A Cassotta, S Bianchi, ...
Science 353 (6301), 823-826, 2016
8422016
The human immune response to Dengue virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity
M Beltramello, KL Williams, CP Simmons, A Macagno, L Simonelli, ...
Cell host & microbe 8 (3), 271-283, 2010
6892010
Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery
F Fumagalli, J Noack, TJ Bergmann, E Cebollero, GB Pisoni, E Fasana, ...
Nature cell biology 18 (11), 1173-1184, 2016
3832016
Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus
D Corti, J Zhao, M Pedotti, L Simonelli, S Agnihothram, C Fett, ...
Proceedings of the National Academy of Sciences 112 (33), 10473-10478, 2015
2252015
Balance of anti-CD123 chimeric antigen receptor binding affinity and density for the targeting of acute myeloid leukemia
S Arcangeli, MC Rotiroti, M Bardelli, L Simonelli, CF Magnani, A Biondi, ...
Molecular therapy 25 (8), 1933-1945, 2017
1602017
A human bi-specific antibody against Zika virus with high therapeutic potential
J Wang, M Bardelli, DA Espinosa, M Pedotti, TS Ng, S Bianchi, ...
Cell 171 (1), 229-241. e15, 2017
1392017
Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice
R De Gasparo, M Pedotti, L Simonelli, P Nickl, F Muecksch, I Cassaniti, ...
Nature 593 (7859), 424-428, 2021
1112021
Computational docking of antibody-antigen complexes, opportunities and pitfalls illustrated by influenza hemagglutinin
M Pedotti, L Simonelli, E Livoti, L Varani
International journal of molecular sciences 12 (1), 226-251, 2011
912011
SARS-CoV-2 neutralizing human recombinant antibodies selected from pre-pandemic healthy donors binding at RBD-ACE2 interface
F Bertoglio, D Meier, N Langreder, S Steinke, U Rand, L Simonelli, ...
Nature communications 12 (1), 1577, 2021
822021
Epitope mapping by solution NMR spectroscopy
M Bardelli, E Livoti, L Simonelli, M Pedotti, A Moraes, AP Valente, ...
Journal of Molecular Recognition 28 (6), 393-400, 2015
542015
Rational engineering of a human anti-dengue antibody through experimentally validated computational docking
L Simonelli, M Pedotti, M Beltramello, E Livoti, L Calzolai, F Sallusto, ...
PloS one 8 (2), e55561, 2013
432013
Human neutralizing antibodies to cold linear epitopes and subdomain 1 of the SARS-CoV-2 spike glycoprotein
F Bianchini, V Crivelli, ME Abernathy, C Guerra, M Palus, J Muri, ...
Science immunology 8 (81), eade0958, 2023
382023
Rapid structural characterization of human antibody–antigen complexes through experimentally validated computational docking
L Simonelli, M Beltramello, Z Yudina, A Macagno, L Calzolai, L Varani
Journal of molecular biology 396 (5), 1491-1507, 2010
302010
Humoral and cell-mediated response against SARS-CoV-2 variants elicited by mRNA vaccine BNT162b2 in healthcare workers: a longitudinal observational study
I Cassaniti, F Bergami, E Percivalle, E Gabanti, JC Sammartino, A Ferrari, ...
Clinical Microbiology and Infection 28 (2), 301. e1-301. e8, 2022
252022
A bispecific immunotweezer prevents soluble PrP oligomers and abolishes prion toxicity
M Bardelli, K Frontzek, L Simonelli, S Hornemann, M Pedotti, F Mazzola, ...
PLoS pathogens 14 (10), e1007335, 2018
222018
Altered cellular distribution and sub-cellular sorting of doppel (Dpl) protein in human astrocytoma cell lines
E Sbalchiero, A Azzalin, S Palumbo, G Barbieri, A Arias, L Simonelli, ...
Analytical Cellular Pathology 30 (4), 337-347, 2008
212008
A conformational switch controlling the toxicity of the prion protein
K Frontzek, M Bardelli, A Senatore, A Henzi, RR Reimann, S Bedir, ...
Nature Structural & Molecular Biology 29 (8), 831-840, 2022
192022
Rational engineering of the lccβ T. versicolor laccase for the mediator-less oxidation of large polycyclic aromatic hydrocarbons
A Chiadò, F Bosco, M Bardelli, L Simonelli, M Pedotti, L Marmo, L Varani
Computational and Structural Biotechnology Journal 19, 2213-2222, 2021
172021
Antibody binding modulates conformational exchange in domain III of dengue virus E protein
AH Moraes, L Simonelli, M Pedotti, FCL Almeida, L Varani, AP Valente
Journal of virology 90 (4), 1802-1811, 2016
142016
Mapping antibody epitopes by solution NMR spectroscopy: practical considerations
L Simonelli, M Pedotti, M Bardelli, S Jurt, O Zerbe, L Varani
Epitope mapping protocols, 29-51, 2018
132018
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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