Francesca Musumeci
Francesca Musumeci
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ATP-competitive inhibitors of mTOR: an update
S Schenone, C Brullo, F Musumeci, M Radi, M Botta
Current medicinal chemistry 18 (20), 2995-3014, 2011
Vascular endothelial growth factor (VEGF) receptors: drugs and new inhibitors
F Musumeci, M Radi, C Brullo, S Schenone
Journal of medicinal chemistry 55 (24), 10797-10822, 2012
Biologically Driven Synthesis of Pyrazolo[3,4-d]pyrimidines As Protein Kinase Inhibitors: An Old Scaffold As a New Tool for Medicinal Chemistry and Chemical …
S Schenone, M Radi, F Musumeci, C Brullo, M Botta
Chemical reviews 114 (14), 7189-7238, 2014
Novel dual Src/Abl inhibitors for hematologic and solid malignancies
S Schenone, C Brullo, F Musumeci, M Botta
Expert opinion on investigational drugs 19 (8), 931-945, 2010
Design, Synthesis, Biological Activity, and ADME Properties of Pyrazolo[3,4-d]pyrimidines Active in Hypoxic Human Leukemia Cells: A Lead Optimization Study
M Radi, E Dreassi, C Brullo, E Crespan, C Tintori, V Bernardo, M Valoti, ...
Journal of medicinal chemistry 54 (8), 2610-2626, 2011
Fyn kinase in brain diseases and cancer: the search for inhibitors
S Schenone, C Brullo, F Musumeci, M Biava, F Falchi, M Botta
Current medicinal chemistry 18 (19), 2921-2942, 2011
A1 receptors ligands: past, present and future trends
S Schenone, C Brullo, F Musumeci, O Bruno, M Botta
Current topics in medicinal chemistry 10 (9), 878-901, 2010
An update on dual Src/Abl inhibitors
F Musumeci, S Schenone, C Brullo, M Botta
Future medicinal chemistry 4 (6), 799-822, 2012
SI113, a specific inhibitor of the Sgk1 kinase activity that counteracts cancer cell proliferation
R Amato, C Talarico, F Ortuso, M Menniti, V Dattilo, R Iuliano, F Gigliotti, ...
Cellular physiology and biochemistry 35 (5), 2006-2018, 2015
Identification of potent c-Src inhibitors strongly affecting the proliferation of human neuroblastoma cells
M Radi, C Brullo, E Crespan, C Tintori, F Musumeci, M Biava, S Schenone, ...
Bioorganic & medicinal chemistry letters 21 (19), 5928-5933, 2011
SI113, a SGK1 inhibitor, potentiates the effects of radiotherapy, modulates the response to oxidative stress and induces cytotoxic autophagy in human glioblastoma multiforme cells
C Talarico, V Dattilo, L D'Antona, A Barone, N Amodio, S Belviso, ...
Oncotarget 7 (13), 15868, 2016
Combining X-ray Crystallography and Molecular Modeling toward the Optimization of Pyrazolo[3,4-d]pyrimidines as Potent c-Src Inhibitors Active in Vivo against …
C Tintori, AL Fallacara, M Radi, C Zamperini, E Dreassi, E Crespan, ...
Journal of medicinal chemistry 58 (1), 347-361, 2015
Design, Synthesis, and Biological Evaluation of Pyrazolo[3,4-d]pyrimidines Active in Vivo on the Bcr-Abl T315I Mutant
M Radi, C Tintori, F Musumeci, C Brullo, C Zamperini, E Dreassi, ...
Journal of medicinal chemistry 56 (13), 5382-5394, 2013
In silico identification and biological evaluation of novel selective serum/glucocorticoid-inducible kinase 1 inhibitors based on the pyrazolo-pyrimidine scaffold
F Ortuso, R Amato, A Artese, L D’antona, G Costa, C Talarico, F Gigliotti, ...
Journal of chemical information and modeling 54 (7), 1828-1832, 2014
Studies on the ATP binding site of Fyn kinase for the identification of new inhibitors and their evaluation as potential agents against tauopathies and tumors
C Tintori, G La Sala, G Vignaroli, L Botta, AL Fallacara, F Falchi, M Radi, ...
Journal of medicinal chemistry 58 (11), 4590-4609, 2015
Click chemistry, a potent tool in medicinal sciences
F Musumeci, S Schenone, A Desogus, E Nieddu, D Deodato, L Botta
Current medicinal chemistry 22 (17), 2022-2050, 2015
A combined targeted/phenotypic approach for the identification of new antiangiogenics agents active on a zebrafish model: From in silico screening to cyclodextrin …
M Radi, L Evensen, E Dreassi, C Zamperini, M Caporicci, F Falchi, ...
Bioorganic & medicinal chemistry letters 22 (17), 5579-5583, 2012
The SGK1 kinase inhibitor SI113 sensitizes theranostic effects of the 64CuCl2 in human glioblastoma multiforme cells
G Catalogna, C Talarico, V Dattilo, V Gangemi, F Calabria, L D’Antona, ...
Cellular Physiology and Biochemistry 43 (1), 108-119, 2017
An update on JAK inhibitors
F Musumeci, C Greco, I Giacchello, AL Fallacara, MM Ibrahim, G Grossi, ...
Current medicinal chemistry 26 (10), 1806-1832, 2019
Substituted pyrazolo [3, 4-b] pyridines as human A 1 adenosine antagonists: Developments in understanding the receptor stereoselectivity
T Tuccinardi, AT Zizzari, C Brullo, S Daniele, F Musumeci, S Schenone, ...
Organic & biomolecular chemistry 9 (12), 4448-4455, 2011
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